SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hcf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 1hcf NEUROTROPHIN-4
(Homo
sapiens) 		3 / 3 ALA A  46
VAL A  44
TRP A 110
 None
 0.89A 1micA-1hcfA:
undetectable
1micB-1hcfA:
undetectable		 1micA-1hcfA:
10.71
1micB-1hcfA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 1hcf NEUROTROPHIN-4
(Homo
sapiens) 		3 / 3 PRO A  71
ASP A  64
ASP A  18
 None
 0.80A 1sqfA-1hcfA:
undetectable		 1sqfA-1hcfA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 1hcf BDNF/NT-3 GROWTH
FACTORS RECEPTOR
(Homo
sapiens) 		3 / 3 TRP X 301
MET X 379
ASN X 356
 None
 1.19A 5uc1B-1hcfX:
undetectable		 5uc1B-1hcfX:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 1hcf BDNF/NT-3 GROWTH
FACTORS RECEPTOR
(Homo
sapiens) 		3 / 3 TRP X 301
MET X 379
ASN X 356
 None
 1.16A 5uc1A-1hcfX:
undetectable		 5uc1A-1hcfX:
17.82