SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hcy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 8 HIS A 384
HIS A 344
HIS A 224
HIS A 348
 CU  A 666 (-3.4A)
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
CU  A 666 (-3.8A)
 0.92A 1bzmA-1hcyA:
undetectable		 1bzmA-1hcyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 9 ILE A 305
GLY A 320
ILE A 321
ILE A 296
ILE A 327
 None
 0.90A 1hshB-1hcyA:
undetectable		 1hshB-1hcyA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ALA A 284
VAL A 286
TRP A 248
 None
 0.88A 1jnoA-1hcyA:
undetectable		 1jnoA-1hcyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ALA A 284
VAL A 286
TRP A 248
 None
 0.88A 1jnoB-1hcyA:
undetectable		 1jnoB-1hcyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ALA A 284
VAL A 286
TRP A 248
 None
 0.84A 1jo3A-1hcyA:
undetectable		 1jo3A-1hcyA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ALA A 284
VAL A 286
TRP A 248
 None
 0.84A 1jo3B-1hcyA:
undetectable		 1jo3B-1hcyA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ALA A 284
VAL A 286
TRP A 248
 None
 0.92A 1jo4A-1hcyA:
undetectable		 1jo4A-1hcyA:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ALA A 284
VAL A 286
TRP A 248
 None
 0.92A 1jo4B-1hcyA:
undetectable		 1jo4B-1hcyA:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 7 PHE A 381
PHE A 380
HIS A 224
HIS A 193
 None
None
CU  A 665 (-3.5A)
None
 0.95A 1lh6A-1hcyA:
undetectable		 1lh6A-1hcyA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ALA A 284
VAL A 286
TRP A 248
 None
 0.84A 1magA-1hcyA:
undetectable		 1magA-1hcyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ALA A 284
VAL A 286
TRP A 248
 None
 0.84A 1magB-1hcyA:
undetectable		 1magB-1hcyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 PHE A  37
TYR A  46
PRO A  39
 None
 1.13A 1mcnA-1hcyA:
2.8
1mcnB-1hcyA:
0.0
1mcnP-1hcyA:
undetectable		 1mcnA-1hcyA:
15.17
1mcnB-1hcyA:
15.17
1mcnP-1hcyA:
0.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 PHE A 277
LEU A 246
MET A 387
 None
 0.91A 1mx1D-1hcyA:
undetectable		 1mx1D-1hcyA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ALA A 284
VAL A 286
TRP A 248
 None
 0.90A 1ng8A-1hcyA:
undetectable		 1ng8A-1hcyA:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ALA A 284
VAL A 286
TRP A 248
 None
 0.90A 1ng8B-1hcyA:
undetectable		 1ng8B-1hcyA:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ALA A 284
VAL A 286
TRP A 248
 None
 0.92A 1nrmA-1hcyA:
undetectable		 1nrmA-1hcyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ALA A 284
VAL A 286
TRP A 248
 None
 0.92A 1nrmB-1hcyA:
undetectable		 1nrmB-1hcyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ALA A 284
VAL A 286
TRP A 248
 None
 0.93A 1nruA-1hcyA:
undetectable		 1nruA-1hcyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ALA A 284
VAL A 286
TRP A 248
 None
 0.93A 1nruB-1hcyA:
undetectable		 1nruB-1hcyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ALA A 284
VAL A 286
TRP A 248
 None
 0.65A 1nt6A-1hcyA:
undetectable		 1nt6A-1hcyA:
6.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ALA A 284
VAL A 286
TRP A 248
 None
 0.65A 1nt6B-1hcyA:
undetectable		 1nt6B-1hcyA:
6.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_B_VDNB102_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 12 HIS A 198
LEU A 227
MET A 368
SER A 379
PHE A 381
 CU  A 665 (-3.1A)
None
None
None
None
 1.50A 1xotB-1hcyA:
undetectable		 1xotB-1hcyA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 11 LEU A 569
LEU A 505
TYR A 462
LYS A 463
LYS A 524
 None
 1.46A 1y4lB-1hcyA:
undetectable		 1y4lB-1hcyA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 LYS A 127
ASP A  48
ASN A  91
 None
 1.02A 2bm9A-1hcyA:
undetectable		 2bm9A-1hcyA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDK_A_C2FA1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 11 LEU A 383
HIS A 348
SER A 342
LEU A 246
HIS A 247
 None
CU  A 666 (-3.8A)
None
None
None
 1.45A 2idkA-1hcyA:
0.0
2idkB-1hcyA:
0.0
2idkC-1hcyA:
0.0
2idkD-1hcyA:
0.0		 2idkA-1hcyA:
18.06
2idkB-1hcyA:
18.06
2idkC-1hcyA:
18.06
2idkD-1hcyA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 8 ALA A   2
VAL A 547
LYS A  10
ASP A  13
 None
 0.99A 2kotB-1hcyA:
undetectable		 2kotB-1hcyA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 4 SER A 330
GLY A 341
HIS A 384
ASP A 377
 None
None
CU  A 666 (-3.4A)
None
 1.38A 2oxtC-1hcyA:
undetectable		 2oxtC-1hcyA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 8 PHE A  99
LEU A 134
ALA A 103
PHE A 115
 None
 0.86A 2vcvP-1hcyA:
0.0		 2vcvP-1hcyA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		6 / 11 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
VAL A 349
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
None
 0.69A 2zweA-1hcyA:
9.8
2zweB-1hcyA:
0.0		 2zweA-1hcyA:
17.45
2zweB-1hcyA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		6 / 11 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
VAL A 349
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
None
 0.74A 2zwfA-1hcyA:
9.7
2zwfB-1hcyA:
0.0		 2zwfA-1hcyA:
17.45
2zwfB-1hcyA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		6 / 11 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
VAL A 349
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
None
 0.74A 2zwgA-1hcyA:
9.8
2zwgB-1hcyA:
0.0		 2zwgA-1hcyA:
17.45
2zwgB-1hcyA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 12 GLY A 185
GLN A 179
GLU A 186
ARG A 382
PHE A 381
 None
 1.39A 3ag4A-1hcyA:
0.0
3ag4B-1hcyA:
0.0
3ag4T-1hcyA:
0.0		 3ag4A-1hcyA:
21.45
3ag4B-1hcyA:
16.06
3ag4T-1hcyA:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 6 LEU A 553
GLY A   6
LEU A 555
SER A 556
 None
 0.83A 3aiaA-1hcyA:
undetectable		 3aiaA-1hcyA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 9 ASP A 200
GLU A 329
HIS A 344
HIS A 224
LEU A 219
 None
None
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
None
 1.19A 3hy7A-1hcyA:
undetectable		 3hy7A-1hcyA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 9 ASP A 200
GLU A 329
HIS A 344
HIS A 224
LEU A 219
 None
None
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
None
 1.14A 3hy7B-1hcyA:
undetectable		 3hy7B-1hcyA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 12 PRO A 484
LEU A 236
ASN A 238
VAL A 181
PHE A 231
 None
 1.46A 3megA-1hcyA:
undetectable		 3megA-1hcyA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 12 LEU A  86
TYR A  46
GLY A  50
THR A  43
LEU A  90
 None
 1.37A 3okxA-1hcyA:
0.1		 3okxA-1hcyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 HIS A 224
HIS A 194
HIS A 198
 CU  A 665 (-3.5A)
CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
 0.61A 3qpkA-1hcyA:
2.1		 3qpkA-1hcyA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 HIS A 224
HIS A 194
HIS A 198
 CU  A 665 (-3.5A)
CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
 0.59A 3qpkB-1hcyA:
2.4		 3qpkB-1hcyA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_D_C2FD1200_0
(GLYCINE
N-METHYLTRANSFERASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 12 LEU A 246
HIS A 247
SER A 342
LEU A 383
HIS A 348
 None
None
None
None
CU  A 666 (-3.8A)
 1.42A 3thrA-1hcyA:
0.0
3thrB-1hcyA:
0.0
3thrC-1hcyA:
0.7
3thrD-1hcyA:
0.9		 3thrA-1hcyA:
18.06
3thrB-1hcyA:
18.06
3thrC-1hcyA:
18.06
3thrD-1hcyA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 LYS A 332
GLU A 206
TRP A 204
 None
 0.91A 3v4tH-1hcyA:
0.0		 3v4tH-1hcyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 12 SER A 330
SER A 334
HIS A 384
LEU A 383
HIS A 348
 None
None
CU  A 666 (-3.4A)
None
CU  A 666 (-3.8A)
 1.46A 3vt7A-1hcyA:
0.0		 3vt7A-1hcyA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 5 GLU A 186
GLY A 185
TYR A 183
GLU A 234
 None
 1.48A 3w9tA-1hcyA:
0.0		 3w9tA-1hcyA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 4 HIS A 344
HIS A 348
HIS A 224
HIS A 384
 CU  A 666 (-3.1A)
CU  A 666 (-3.8A)
CU  A 665 (-3.5A)
CU  A 666 (-3.4A)
 1.23A 4ef3A-1hcyA:
undetectable		 4ef3A-1hcyA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 8 TYR A 431
ILE A 188
VAL A 195
THR A 196
 None
 0.85A 4ma7A-1hcyA:
undetectable		 4ma7A-1hcyA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 7 HIS A  16
ASP A  19
SER A 535
PHE A 536
 None
 1.28A 4odjA-1hcyA:
undetectable		 4odjA-1hcyA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		6 / 7 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
ALA A 374
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
None
 0.82A 4p6sA-1hcyA:
9.4		 4p6sA-1hcyA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 7 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
 0.79A 4p6sB-1hcyA:
9.5		 4p6sB-1hcyA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 7 HIS A 344
HIS A 348
HIS A 194
HIS A 198
 CU  A 666 (-3.1A)
CU  A 666 (-3.8A)
CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
 0.89A 4p6sB-1hcyA:
9.5		 4p6sB-1hcyA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 7 ARG A 620
THR A 477
GLY A 589
THR A 587
 None
 0.93A 4qwpB-1hcyA:
undetectable		 4qwpB-1hcyA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 7 LEU A  18
PRO A 135
LEU A 119
TYR A 120
 None
 0.97A 4z4fA-1hcyA:
0.0		 4z4fA-1hcyA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 7 HIS A  16
ASP A  19
SER A 535
PHE A 536
 None
 1.28A 5a1iA-1hcyA:
undetectable		 5a1iA-1hcyA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 7 VAL A 416
ILE A 464
PHE A 478
VAL A 584
 None
 0.60A 5bmvC-1hcyA:
undetectable		 5bmvC-1hcyA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		6 / 7 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
ALA A 374
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
None
 0.83A 5i3aA-1hcyA:
9.2		 5i3aA-1hcyA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		6 / 7 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
ALA A 374
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
None
 0.83A 5i3aB-1hcyA:
9.2		 5i3aB-1hcyA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 7 HIS A 344
HIS A 348
HIS A 194
HIS A 198
 CU  A 666 (-3.1A)
CU  A 666 (-3.8A)
CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
 0.92A 5i3aB-1hcyA:
9.2		 5i3aB-1hcyA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		6 / 7 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
ALA A 374
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
None
 0.85A 5i3bA-1hcyA:
9.4		 5i3bA-1hcyA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 7 HIS A 348
HIS A 344
HIS A 198
HIS A 194
ALA A 374
 CU  A 666 (-3.8A)
CU  A 666 (-3.1A)
CU  A 665 (-3.1A)
CU  A 665 (-3.0A)
None
 1.15A 5i3bA-1hcyA:
9.4		 5i3bA-1hcyA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 5 HIS A 194
HIS A 198
HIS A 348
ALA A 374
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.8A)
None
 0.90A 5i3bB-1hcyA:
9.3		 5i3bB-1hcyA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 5 HIS A 348
HIS A 344
HIS A 194
ALA A 374
 CU  A 666 (-3.8A)
CU  A 666 (-3.1A)
CU  A 665 (-3.0A)
None
 1.01A 5i3bB-1hcyA:
9.3		 5i3bB-1hcyA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 5 HIS A 348
HIS A 384
HIS A 194
ALA A 374
 CU  A 666 (-3.8A)
CU  A 666 (-3.4A)
CU  A 665 (-3.0A)
None
 1.22A 5i3bB-1hcyA:
9.3		 5i3bB-1hcyA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 PRO A 621
ARG A 620
GLU A 627
 None
 0.95A 5j6hA-1hcyA:
2.7		 5j6hA-1hcyA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 8 VAL A 452
ILE A 188
THR A 146
VAL A 150
VAL A 168
 None
 1.45A 5l94A-1hcyA:
undetectable		 5l94A-1hcyA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 8 ILE A 448
PRO A 163
ALA A 157
PHE A 166
 None
 0.90A 5m0oC-1hcyA:
0.0		 5m0oC-1hcyA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 10 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
 0.74A 5m8nA-1hcyA:
8.2		 5m8nA-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 10 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
 0.78A 5m8nB-1hcyA:
8.1		 5m8nB-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 9 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
 0.71A 5m8nC-1hcyA:
8.0		 5m8nC-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 7 HIS A 198
HIS A 344
ASN A 345
HIS A 348
 CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
 0.67A 5m8rA-1hcyA:
7.6		 5m8rA-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 8 HIS A 198
HIS A 344
ASN A 345
HIS A 348
 CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
 0.66A 5m8rB-1hcyA:
8.1		 5m8rB-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 8 HIS A 198
HIS A 344
ASN A 345
HIS A 348
 CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
 0.73A 5m8rC-1hcyA:
8.1		 5m8rC-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 8 HIS A 198
HIS A 344
ASN A 345
HIS A 348
 CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
 0.71A 5m8rD-1hcyA:
7.2		 5m8rD-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 5 HIS A 198
HIS A 194
HIS A 344
HIS A 224
HIS A 384
 CU  A 665 (-3.1A)
CU  A 665 (-3.0A)
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
CU  A 666 (-3.4A)
 1.22A 5mejA-1hcyA:
undetectable		 5mejA-1hcyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 5 HIS A 198
HIS A 194
HIS A 344
HIS A 224
HIS A 384
 CU  A 665 (-3.1A)
CU  A 665 (-3.0A)
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
CU  A 666 (-3.4A)
 1.21A 5mewA-1hcyA:
undetectable		 5mewA-1hcyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 5 HIS A 198
HIS A 194
HIS A 344
HIS A 224
HIS A 384
 CU  A 665 (-3.1A)
CU  A 665 (-3.0A)
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
CU  A 666 (-3.4A)
 1.22A 5mhuA-1hcyA:
undetectable		 5mhuA-1hcyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 5 HIS A 198
HIS A 194
HIS A 344
HIS A 224
HIS A 384
 CU  A 665 (-3.1A)
CU  A 665 (-3.0A)
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
CU  A 666 (-3.4A)
 1.22A 5mhvA-1hcyA:
undetectable		 5mhvA-1hcyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 4 HIS A 198
HIS A 384
HIS A 344
HIS A 224
 CU  A 665 (-3.1A)
CU  A 666 (-3.4A)
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
 1.01A 5mhwA-1hcyA:
undetectable		 5mhwA-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 4 HIS A 198
HIS A 384
HIS A 344
HIS A 224
 CU  A 665 (-3.1A)
CU  A 666 (-3.4A)
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
 1.01A 5mhxA-1hcyA:
undetectable		 5mhxA-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 4 HIS A 198
HIS A 384
HIS A 344
HIS A 224
 CU  A 665 (-3.1A)
CU  A 666 (-3.4A)
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
 1.00A 5mhyA-1hcyA:
undetectable		 5mhyA-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 4 HIS A 198
HIS A 384
HIS A 344
HIS A 224
 CU  A 665 (-3.1A)
CU  A 666 (-3.4A)
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
 1.00A 5mhzA-1hcyA:
undetectable		 5mhzA-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 4 HIS A 198
HIS A 384
HIS A 344
HIS A 224
 CU  A 665 (-3.1A)
CU  A 666 (-3.4A)
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
 1.00A 5mi1A-1hcyA:
undetectable		 5mi1A-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 4 HIS A 198
HIS A 384
HIS A 344
HIS A 224
 CU  A 665 (-3.1A)
CU  A 666 (-3.4A)
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
 1.00A 5mi2A-1hcyA:
undetectable		 5mi2A-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 4 HIS A 198
HIS A 384
HIS A 344
HIS A 224
 CU  A 665 (-3.1A)
CU  A 666 (-3.4A)
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
 1.00A 5miaA-1hcyA:
undetectable		 5miaA-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 4 HIS A 198
HIS A 384
HIS A 344
HIS A 224
 CU  A 665 (-3.1A)
CU  A 666 (-3.4A)
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
 1.00A 5mibA-1hcyA:
undetectable		 5mibA-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 4 HIS A 198
HIS A 384
HIS A 344
HIS A 224
 CU  A 665 (-3.1A)
CU  A 666 (-3.4A)
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
 1.00A 5micA-1hcyA:
2.0		 5micA-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 4 HIS A 198
HIS A 384
HIS A 344
HIS A 224
 CU  A 665 (-3.1A)
CU  A 666 (-3.4A)
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
 1.00A 5midA-1hcyA:
undetectable		 5midA-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 4 HIS A 198
HIS A 384
HIS A 344
HIS A 224
 CU  A 665 (-3.1A)
CU  A 666 (-3.4A)
CU  A 666 (-3.1A)
CU  A 665 (-3.5A)
 1.00A 5mieA-1hcyA:
undetectable		 5mieA-1hcyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 HIS A 193
HIS A 194
HIS A 198
 None
CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
 0.95A 5oexA-1hcyA:
undetectable		 5oexA-1hcyA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 8 GLU A 329
PHE A 203
TRP A 204
TRP A 205
 None
 1.45A 5oh1C-1hcyA:
0.0		 5oh1C-1hcyA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 7 LEU A  18
PRO A 135
LEU A 119
TYR A 120
 None
 1.00A 5t7bA-1hcyA:
0.0		 5t7bA-1hcyA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ARG A 107
PRO A  24
TYR A  27
 None
 1.06A 5tzoB-1hcyA:
undetectable		 5tzoB-1hcyA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		5 / 12 ILE A 448
GLN A 430
ILE A 188
TYR A 138
ILE A 151
 None
 1.05A 5y2tB-1hcyA:
0.0		 5y2tB-1hcyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		6 / 11 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
VAL A 349
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
None
 0.78A 5z0fA-1hcyA:
0.0
5z0fB-1hcyA:
0.0		 5z0fA-1hcyA:
9.38
5z0fB-1hcyA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		6 / 11 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
VAL A 349
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
None
 0.76A 5z0gA-1hcyA:
9.7
5z0gB-1hcyA:
0.0		 5z0gA-1hcyA:
9.38
5z0gB-1hcyA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		6 / 11 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
VAL A 349
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
None
 0.76A 5z0hA-1hcyA:
9.7
5z0hB-1hcyA:
0.0		 5z0hA-1hcyA:
9.38
5z0hB-1hcyA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		6 / 11 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
VAL A 349
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
None
 0.76A 5z0iA-1hcyA:
9.7
5z0iB-1hcyA:
0.0		 5z0iA-1hcyA:
9.38
5z0iB-1hcyA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		6 / 11 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
VAL A 349
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
None
 0.73A 5z0jA-1hcyA:
9.7
5z0jB-1hcyA:
0.0		 5z0jA-1hcyA:
9.38
5z0jB-1hcyA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		6 / 11 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
VAL A 349
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
None
 0.71A 5z0kA-1hcyA:
9.6
5z0kB-1hcyA:
0.0		 5z0kA-1hcyA:
9.38
5z0kB-1hcyA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		6 / 11 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
VAL A 349
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
None
 0.76A 5z0lA-1hcyA:
9.6
5z0lB-1hcyA:
0.0		 5z0lA-1hcyA:
9.38
5z0lB-1hcyA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		6 / 11 HIS A 194
HIS A 198
HIS A 344
ASN A 345
HIS A 348
VAL A 349
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 666 (-3.1A)
None
CU  A 666 (-3.8A)
None
 0.85A 5z0mA-1hcyA:
9.7
5z0mB-1hcyA:
0.0		 5z0mA-1hcyA:
9.89
5z0mB-1hcyA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 HIS A 344
HIS A 348
HIS A 384
 CU  A 666 (-3.1A)
CU  A 666 (-3.8A)
CU  A 666 (-3.4A)
 0.54A 5zrdA-1hcyA:
5.6		 5zrdA-1hcyA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 5 HIS A 194
HIS A 198
PHE A 220
HIS A 224
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
None
CU  A 665 (-3.5A)
 0.83A 5zrdB-1hcyA:
3.4		 5zrdB-1hcyA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 5 HIS A 344
HIS A 348
PHE A 380
HIS A 384
 CU  A 666 (-3.1A)
CU  A 666 (-3.8A)
None
CU  A 666 (-3.4A)
 0.45A 5zrdB-1hcyA:
3.4		 5zrdB-1hcyA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 5 HIS A 194
HIS A 198
HIS A 224
PHE A 380
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 665 (-3.5A)
None
 0.87A 5zrdB-1hcyA:
3.4		 5zrdB-1hcyA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 5 HIS A 344
HIS A 348
HIS A 384
PHE A 220
 CU  A 666 (-3.1A)
CU  A 666 (-3.8A)
CU  A 666 (-3.4A)
None
 1.09A 5zrdB-1hcyA:
3.4		 5zrdB-1hcyA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 5 HIS A 194
HIS A 198
HIS A 224
PHE A 380
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 665 (-3.5A)
None
 0.95A 5zrdC-1hcyA:
3.1		 5zrdC-1hcyA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 5 HIS A 344
HIS A 348
HIS A 384
PHE A 220
 CU  A 666 (-3.1A)
CU  A 666 (-3.8A)
CU  A 666 (-3.4A)
None
 1.13A 5zrdC-1hcyA:
3.1		 5zrdC-1hcyA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 5 HIS A 194
HIS A 198
HIS A 224
PHE A 380
 CU  A 665 (-3.0A)
CU  A 665 (-3.1A)
CU  A 665 (-3.5A)
None
 0.88A 5zrdD-1hcyA:
2.6		 5zrdD-1hcyA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 5 HIS A 344
HIS A 348
HIS A 384
PHE A 220
 CU  A 666 (-3.1A)
CU  A 666 (-3.8A)
CU  A 666 (-3.4A)
None
 1.08A 5zrdD-1hcyA:
2.6		 5zrdD-1hcyA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 6 TYR A  27
ASP A 544
GLN A   9
VAL A 547
 None
 1.26A 6djzB-1hcyA:
0.0		 6djzB-1hcyA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		4 / 7 HIS A  16
ASP A  19
SER A 535
PHE A 536
 None
 1.27A 6g6rA-1hcyA:
undetectable		 6g6rA-1hcyA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 HIS A 224
HIS A 198
HIS A 194
 CU  A 665 (-3.5A)
CU  A 665 (-3.1A)
CU  A 665 (-3.0A)
 0.73A 6giqa-1hcyA:
undetectable		 6giqa-1hcyA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1hcy ARTHROPODAN
HEMOCYANIN
(Panulirus
interruptus) 		3 / 3 ARG A 177
PHE A 184
PHE A 256
 None
 1.06A 6nknC-1hcyA:
0.5
6nknJ-1hcyA:
0.0		 6nknC-1hcyA:
16.21
6nknJ-1hcyA:
6.85