SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hdf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		4 / 7 LEU A  73
ALA A  58
VAL A  96
TYR A  18
 None
 0.68A 1epbA-1hdfA:
undetectable		 1epbA-1hdfA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 12 THR A  56
LEU A  17
VAL A  47
PHE A  37
VAL A  30
 None
 1.32A 1q23C-1hdfA:
undetectable		 1q23C-1hdfA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 10 THR A  56
LEU A  17
VAL A  47
PHE A  37
VAL A  30
 None
 1.28A 1q23E-1hdfA:
0.0		 1q23E-1hdfA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 11 THR A  56
LEU A  17
VAL A  47
PHE A  37
VAL A  30
 None
 1.35A 1q23F-1hdfA:
undetectable		 1q23F-1hdfA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 11 THR A  56
LEU A  17
VAL A  47
PHE A  37
VAL A  30
 None
 1.31A 1q23I-1hdfA:
undetectable		 1q23I-1hdfA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 11 THR A  56
LEU A  17
VAL A  47
PHE A  37
VAL A  30
 None
 1.35A 1q23J-1hdfA:
0.0		 1q23J-1hdfA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 10 THR A  56
LEU A  17
VAL A  47
PHE A  37
VAL A  30
 None
 1.37A 1q23K-1hdfA:
0.0		 1q23K-1hdfA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 11 THR A  56
LEU A  17
VAL A  47
PHE A  37
VAL A  30
 None
 1.40A 1q23L-1hdfA:
undetectable		 1q23L-1hdfA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		3 / 3 ASP A  81
ILE A  91
VAL A  52
 None
 0.68A 2avvD-1hdfA:
undetectable		 2avvD-1hdfA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 12 THR A  56
LEU A  17
VAL A  47
PHE A  37
VAL A  30
 None
 1.35A 3u9fB-1hdfA:
undetectable
3u9fC-1hdfA:
0.0		 3u9fB-1hdfA:
18.69
3u9fC-1hdfA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 10 THR A  56
LEU A  17
VAL A  47
PHE A  37
VAL A  30
 None
 1.37A 3u9fE-1hdfA:
undetectable		 3u9fE-1hdfA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 12 THR A  56
LEU A  17
VAL A  47
PHE A  37
VAL A  30
 None
 1.31A 3u9fH-1hdfA:
undetectable
3u9fI-1hdfA:
0.0		 3u9fH-1hdfA:
18.69
3u9fI-1hdfA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 10 THR A  56
LEU A  17
VAL A  47
PHE A  37
VAL A  30
 None
 1.34A 3u9fI-1hdfA:
undetectable		 3u9fI-1hdfA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 12 THR A  56
LEU A  17
VAL A  47
PHE A  37
VAL A  30
 None
 1.37A 3u9fJ-1hdfA:
undetectable
3u9fK-1hdfA:
0.0		 3u9fJ-1hdfA:
18.69
3u9fK-1hdfA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 11 THR A  56
LEU A  17
VAL A  47
PHE A  37
VAL A  30
 None
 1.39A 3u9fN-1hdfA:
undetectable
3u9fO-1hdfA:
0.0		 3u9fN-1hdfA:
18.69
3u9fO-1hdfA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 9 THR A  56
LEU A  17
VAL A  47
PHE A  37
VAL A  30
 None
 1.32A 3u9fP-1hdfA:
0.0		 3u9fP-1hdfA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 12 THR A  56
LEU A  17
VAL A  47
PHE A  37
VAL A  30
 None
 1.34A 3u9fP-1hdfA:
0.0
3u9fS-1hdfA:
0.0		 3u9fP-1hdfA:
18.69
3u9fS-1hdfA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 12 LEU A  82
ASN A  88
LEU A  87
ALA A  90
MET A  94
 None
CA  A1101 ( 4.6A)
None
CA  A1102 (-4.4A)
None
 0.97A 4fn9B-1hdfA:
undetectable		 4fn9B-1hdfA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		5 / 12 LEU A  82
ASN A  88
LEU A  87
ALA A  90
MET A  94
 None
CA  A1101 ( 4.6A)
None
CA  A1102 (-4.4A)
None
 1.08A 4ltwA-1hdfA:
undetectable		 4ltwA-1hdfA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		3 / 3 VAL A  40
SER A  41
TRP A  28
 None
 1.08A 5jwaA-1hdfA:
undetectable		 5jwaA-1hdfA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		3 / 3 ASP A  45
ASN A  44
ASP A  36
 CA  A1102 (-2.8A)
CA  A1102 ( 4.5A)
None
 0.85A 5vopA-1hdfA:
undetectable		 5vopA-1hdfA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		3 / 3 ASP A  45
ASN A  44
ASP A  64
 CA  A1102 (-2.8A)
CA  A1102 ( 4.5A)
None
 0.76A 5vopA-1hdfA:
undetectable		 5vopA-1hdfA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		3 / 3 ASP A  45
ASN A  44
ASP A  36
 CA  A1102 (-2.8A)
CA  A1102 ( 4.5A)
None
 0.82A 5vopB-1hdfA:
undetectable		 5vopB-1hdfA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1hdf SPHERULIN 3A
(Physarum
polycephalum) 		3 / 3 ASP A  45
ASN A  44
ASP A  64
 CA  A1102 (-2.8A)
CA  A1102 ( 4.5A)
None
 0.74A 5vopB-1hdfA:
undetectable		 5vopB-1hdfA:
15.82