SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hdi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
4 / 8 GLY A 337
TRP A 335
GLY A 212
VAL A 327
None
0.87A 1dbbH-1hdiA:
undetectable
1dbbL-1hdiA:
undetectable
1dbbH-1hdiA:
19.95
1dbbL-1hdiA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDR_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ALA A 164
PHE A  24
ILE A  46
LEU A  84
THR A 167
None
None
None
None
3PG  A 419 ( 4.5A)
1.09A 1ddrB-1hdiA:
undetectable
1ddrB-1hdiA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 GLY A 373
GLY A 395
GLY A 394
PHE A 165
PHE A 196
None
0.86A 1dx6A-1hdiA:
undetectable
1dx6A-1hdiA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ALA A 164
PHE A  24
ILE A  46
LEU A  84
THR A 167
None
None
None
None
3PG  A 419 ( 4.5A)
1.05A 1dyiA-1hdiA:
undetectable
1dyiA-1hdiA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
4 / 7 LEU A   6
ALA A 184
VAL A 161
VAL A 159
None
0.81A 1epbA-1hdiA:
undetectable
1epbA-1hdiA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
4 / 8 LEU A   6
ALA A 184
VAL A 161
VAL A 159
None
0.85A 1epbB-1hdiA:
0.0
1epbB-1hdiA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 11 ILE A 370
SER A 398
GLY A 394
GLY A 372
PHE A 196
None
1.29A 1ho5A-1hdiA:
undetectable
1ho5A-1hdiA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ALA A 164
PHE A  24
ILE A  46
LEU A  84
THR A 167
None
None
None
None
3PG  A 419 ( 4.5A)
1.05A 1jolA-1hdiA:
undetectable
1jolA-1hdiA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_B_FFOB361_0
(DIHYDROFOLATE
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ALA A 164
PHE A  24
ILE A  46
LEU A  84
THR A 167
None
None
None
None
3PG  A 419 ( 4.5A)
1.07A 1jolB-1hdiA:
undetectable
1jolB-1hdiA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KVL_A_CLSA371_1
(BETA-LACTAMASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 10 GLY A 372
LEU A 402
ASN A 336
THR A 393
GLY A 394
None
1.31A 1kvlA-1hdiA:
undetectable
1kvlA-1hdiA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ALA A 348
PHE A 342
GLY A 350
GLU A 343
GLU A 293
None
None
None
AMP  A 417 (-2.8A)
None
1.15A 1mj2A-1hdiA:
undetectable
1mj2B-1hdiA:
undetectable
1mj2A-1hdiA:
13.77
1mj2B-1hdiA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 10 GLU A 343
GLU A 293
ALA A 348
PHE A 342
GLY A 350
AMP  A 417 (-2.8A)
None
None
None
None
1.18A 1mjqC-1hdiA:
undetectable
1mjqD-1hdiA:
undetectable
1mjqC-1hdiA:
13.77
1mjqD-1hdiA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 11 GLU A 343
GLU A 293
ALA A 348
PHE A 342
GLY A 350
AMP  A 417 (-2.8A)
None
None
None
None
1.18A 1mjqI-1hdiA:
undetectable
1mjqJ-1hdiA:
undetectable
1mjqI-1hdiA:
13.77
1mjqJ-1hdiA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 LEU A 117
LEU A  84
VAL A  26
ALA A  42
ALA A  41
None
1.10A 1n5xA-1hdiA:
undetectable
1n5xA-1hdiA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 LEU A 117
LEU A  84
VAL A  26
ALA A  42
ALA A  41
None
1.09A 1n5xB-1hdiA:
undetectable
1n5xB-1hdiA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 GLY A 373
GLY A 395
GLY A 394
PHE A 165
PHE A 196
None
0.88A 1qtiA-1hdiA:
undetectable
1qtiA-1hdiA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 GLY A 373
GLY A 395
GLY A 394
PHE A 196
PHE A 165
None
0.94A 1qtiA-1hdiA:
undetectable
1qtiA-1hdiA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 GLY A 373
GLY A 395
GLY A 394
PHE A 165
PHE A 196
None
0.88A 1w6rA-1hdiA:
undetectable
1w6rA-1hdiA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 GLY A 373
GLY A 395
GLY A 394
PHE A 196
PHE A 165
None
0.97A 1w6rA-1hdiA:
undetectable
1w6rA-1hdiA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 8 GLY A 394
GLY A 395
GLY A 396
SER A 398
ALA A 397
None
1.08A 1yajC-1hdiA:
undetectable
1yajC-1hdiA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
4 / 6 GLY A 371
SER A 392
LEU A 402
HIS A 390
None
0.91A 1yajF-1hdiA:
undetectable
1yajF-1hdiA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
4 / 4 GLY A 372
SER A 392
ILE A 369
HIS A 390
None
1.14A 1yajJ-1hdiA:
undetectable
1yajJ-1hdiA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
3 / 3 PHE A 291
VAL A 341
TRP A 344
None
AMP  A 417 (-3.4A)
None
0.77A 2cc8A-1hdiA:
0.0
2cc8A-1hdiA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
3 / 3 PHE A 291
VAL A 341
TRP A 344
None
AMP  A 417 (-3.4A)
None
0.77A 2ccbA-1hdiA:
undetectable
2ccbA-1hdiA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
3 / 3 PHE A 291
VAL A 341
TRP A 344
None
AMP  A 417 (-3.4A)
None
0.77A 2vx9A-1hdiA:
0.0
2vx9A-1hdiA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ILE A 223
ASN A 336
GLY A 212
GLY A 337
ASP A 374
None
None
None
None
MG  A 418 ( 3.0A)
1.25A 2zw9A-1hdiA:
undetectable
2zw9A-1hdiA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OPE_A_SAMA7_0
(PROBABLE
HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 GLY A 365
HIS A 390
TYR A 195
GLN A 332
ILE A 369
None
1.33A 3opeA-1hdiA:
undetectable
3opeA-1hdiA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
3 / 3 LEU A  63
GLU A 119
SER A  61
None
0.63A 4ccqA-1hdiA:
1.0
4ccqA-1hdiA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 GLY A 373
GLY A 395
GLY A 394
PHE A 165
PHE A 196
None
0.88A 4ey6A-1hdiA:
undetectable
4ey6A-1hdiA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 GLY A 373
GLY A 395
GLY A 394
PHE A 196
PHE A 165
None
0.93A 4ey6A-1hdiA:
undetectable
4ey6A-1hdiA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 GLY A 373
GLY A 395
GLY A 394
PHE A 165
PHE A 196
None
0.88A 4ey6B-1hdiA:
undetectable
4ey6B-1hdiA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 GLY A 373
GLY A 395
GLY A 394
PHE A 196
PHE A 165
None
0.94A 4ey6B-1hdiA:
undetectable
4ey6B-1hdiA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FHB_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ALA A 164
PHE A  24
ILE A  46
LEU A  84
THR A 167
None
None
None
None
3PG  A 419 ( 4.5A)
1.00A 4fhbA-1hdiA:
undetectable
4fhbA-1hdiA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
3 / 3 LEU A 407
PRO A 408
ARG A  38
None
None
3PG  A 419 (-2.4A)
0.42A 4klrB-1hdiA:
2.0
4klrB-1hdiA:
19.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
12 / 12 GLY A 213
ALA A 214
GLY A 237
GLY A 238
PHE A 241
THR A 254
LEU A 256
PHE A 291
MET A 311
LEU A 313
GLY A 340
VAL A 341
AMP  A 417 ( 3.9A)
AMP  A 417 (-3.7A)
AMP  A 417 (-3.4A)
AMP  A 417 (-3.4A)
None
None
AMP  A 417 (-4.5A)
None
None
AMP  A 417 (-4.6A)
AMP  A 417 (-3.5A)
AMP  A 417 (-3.4A)
0.40A 4o33A-1hdiA:
62.2
4o33A-1hdiA:
91.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
6 / 12 GLY A 213
GLY A 237
PHE A 291
MET A 311
LEU A 313
VAL A 341
AMP  A 417 ( 3.9A)
AMP  A 417 (-3.4A)
None
None
AMP  A 417 (-4.6A)
AMP  A 417 (-3.4A)
1.11A 4o33A-1hdiA:
62.2
4o33A-1hdiA:
91.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
11 / 12 GLY A 213
ALA A 214
GLY A 237
GLY A 238
PHE A 241
THR A 254
LEU A 256
PHE A 291
LEU A 313
GLY A 340
VAL A 341
AMP  A 417 ( 3.9A)
AMP  A 417 (-3.7A)
AMP  A 417 (-3.4A)
AMP  A 417 (-3.4A)
None
None
AMP  A 417 (-4.5A)
None
AMP  A 417 (-4.6A)
AMP  A 417 (-3.5A)
AMP  A 417 (-3.4A)
0.38A 4o3fA-1hdiA:
60.1
4o3fA-1hdiA:
90.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
11 / 12 GLY A 213
ALA A 214
GLY A 237
GLY A 238
PHE A 241
THR A 254
PHE A 291
MET A 311
LEU A 313
GLY A 340
VAL A 341
AMP  A 417 ( 3.9A)
AMP  A 417 (-3.7A)
AMP  A 417 (-3.4A)
AMP  A 417 (-3.4A)
None
None
None
None
AMP  A 417 (-4.6A)
AMP  A 417 (-3.5A)
AMP  A 417 (-3.4A)
0.39A 4o3fA-1hdiA:
60.1
4o3fA-1hdiA:
90.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ALA A 164
PHE A  24
ILE A  46
LEU A  84
THR A 167
None
None
None
None
3PG  A 419 ( 4.5A)
0.91A 4pstA-1hdiA:
undetectable
4pstA-1hdiA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSY_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ALA A 164
PHE A  24
ILE A  46
LEU A  84
THR A 167
None
None
None
None
3PG  A 419 ( 4.5A)
0.94A 4psyA-1hdiA:
undetectable
4psyA-1hdiA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLE_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ALA A 164
PHE A  24
ILE A  46
LEU A  84
THR A 167
None
None
None
None
3PG  A 419 ( 4.5A)
1.03A 4qleA-1hdiA:
undetectable
4qleA-1hdiA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
4 / 8 ILE A 252
LEU A 268
LEU A 281
PHE A 241
None
1.02A 4r38B-1hdiA:
undetectable
4r38B-1hdiA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 9 ILE A 252
LEU A 268
LEU A 281
ILE A 279
PHE A 241
None
1.13A 4r38C-1hdiA:
undetectable
4r38C-1hdiA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 8 ILE A 252
LEU A 268
LEU A 281
ILE A 279
PHE A 241
None
1.14A 4r38D-1hdiA:
undetectable
4r38D-1hdiA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RGC_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ALA A 164
PHE A  24
ILE A  46
LEU A  84
THR A 167
None
None
None
None
3PG  A 419 ( 4.5A)
0.91A 4rgcA-1hdiA:
undetectable
4rgcA-1hdiA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 LEU A 268
LEU A 211
LYS A 219
VAL A 230
ALA A 209
None
None
AMP  A 417 (-2.8A)
None
None
1.07A 4x1kD-1hdiA:
undetectable
4x1kD-1hdiA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ALA A 164
PHE A  24
ILE A  46
LEU A  84
THR A 167
None
None
None
None
3PG  A 419 ( 4.5A)
1.00A 4x5gA-1hdiA:
undetectable
4x5gA-1hdiA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YNM_A_SAMA2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 GLY A 365
HIS A 390
TYR A 195
GLN A 332
ILE A 369
None
1.40A 4ynmA-1hdiA:
undetectable
4ynmA-1hdiA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YNM_B_SAMB2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 GLY A 365
HIS A 390
TYR A 195
GLN A 332
ILE A 369
None
1.40A 4ynmB-1hdiA:
undetectable
4ynmB-1hdiA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YNP_B_SAMB2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 10 GLY A 365
HIS A 390
TYR A 195
GLN A 332
ILE A 369
None
1.28A 4ynpB-1hdiA:
undetectable
4ynpB-1hdiA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPA_A_SAMA3004_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 GLY A 365
HIS A 390
TYR A 195
GLN A 332
ILE A 369
None
1.31A 4ypaA-1hdiA:
undetectable
4ypaA-1hdiA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPA_B_SAMB2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 GLY A 365
HIS A 390
TYR A 195
GLN A 332
ILE A 369
None
1.33A 4ypaB-1hdiA:
undetectable
4ypaB-1hdiA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPA_C_SAMC2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 GLY A 365
HIS A 390
TYR A 195
GLN A 332
ILE A 369
None
1.27A 4ypaC-1hdiA:
undetectable
4ypaC-1hdiA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 9 ARG A 170
ALA A 171
LEU A 407
GLY A 409
GLU A 400
3PG  A 419 (-4.0A)
None
None
None
None
1.20A 5dqfA-1hdiA:
undetectable
5dqfA-1hdiA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ALA A 164
PHE A  24
ILE A  46
LEU A  84
THR A 167
None
None
None
None
3PG  A 419 ( 4.5A)
1.08A 5e8qB-1hdiA:
undetectable
5e8qB-1hdiA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ALA A 164
PHE A  24
ILE A  46
LEU A  84
THR A 167
None
None
None
None
3PG  A 419 ( 4.5A)
1.08A 5eajB-1hdiA:
undetectable
5eajB-1hdiA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ALA A 164
PHE A  24
ILE A  46
LEU A  84
THR A 167
None
None
None
None
3PG  A 419 ( 4.5A)
1.08A 5ujxB-1hdiA:
2.0
5ujxB-1hdiA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
4 / 8 PRO A 307
ALA A 303
THR A 301
TRP A 310
None
0.81A 5x2tI-1hdiA:
undetectable
5x2tJ-1hdiA:
undetectable
5x2tK-1hdiA:
undetectable
5x2tL-1hdiA:
undetectable
5x2tI-1hdiA:
17.76
5x2tJ-1hdiA:
16.80
5x2tK-1hdiA:
17.76
5x2tL-1hdiA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 GLY A  68
GLY A 131
PRO A  66
LEU A 153
PHE A 149
None
1.07A 5ybbA-1hdiA:
undetectable
5ybbA-1hdiA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJS_A_SALA603_0
(VICILIN-LIKE
ANTIMICROBIAL
PEPTIDES 2-2)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 11 PHE A 241
GLY A 237
VAL A 341
PHE A 291
GLY A 340
None
AMP  A 417 (-3.4A)
AMP  A 417 (-3.4A)
None
AMP  A 417 (-3.5A)
1.35A 5yjsA-1hdiA:
0.0
5yjsA-1hdiA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ALA A 164
PHE A  24
ILE A  46
LEU A  84
THR A 167
None
None
None
None
3PG  A 419 ( 4.5A)
0.91A 5z6jA-1hdiA:
undetectable
5z6jA-1hdiA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
5 / 12 ALA A 164
PHE A  24
ILE A  46
LEU A  84
THR A 167
None
None
None
None
3PG  A 419 ( 4.5A)
0.91A 5z6kA-1hdiA:
undetectable
5z6kA-1hdiA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
1hdi PHOSPHOGLYCERATE
KINASE

(Sus
scrofa)
3 / 3 MET A 175
ASP A  23
ARG A  65
None
3PG  A 419 (-2.9A)
3PG  A 419 (-4.0A)
1.11A 5z6kA-1hdiA:
0.0
5z6kA-1hdiA:
18.93