SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1he3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA2_0
(ACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		4 / 4 THR A 166
PRO A 201
THR A 199
PRO A 152
 None
None
None
MBV  A1207 ( 4.5A)
 0.90A 1a7yA-1he3A:
undetectable
1a7yC-1he3A:
undetectable		 1a7yA-1he3A:
20.00
1a7yC-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 199
THR A 166
PRO A 201
 None
 0.83A 1a7yA-1he3A:
undetectable		 1a7yA-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 199
THR A 166
PRO A 201
 None
 0.83A 1a7yB-1he3A:
undetectable		 1a7yB-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 199
THR A 166
PRO A 201
 None
 0.85A 1fjaC-1he3A:
undetectable		 1fjaC-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 199
THR A 166
PRO A 201
 None
 0.85A 1fjaD-1he3A:
undetectable		 1fjaD-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 166
PRO A 201
THR A 199
 None
 0.80A 1i3wE-1he3A:
undetectable		 1i3wE-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 199
THR A 166
PRO A 201
 None
 0.87A 1i3wE-1he3A:
undetectable		 1i3wE-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 199
THR A 166
PRO A 201
 None
 0.84A 1i3wF-1he3A:
undetectable		 1i3wF-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 166
PRO A 201
THR A 199
 None
 0.83A 1i3wG-1he3A:
undetectable		 1i3wG-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 199
THR A 166
PRO A 201
 None
 0.86A 1i3wH-1he3A:
undetectable		 1i3wH-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 199
THR A 166
PRO A 201
 None
 0.81A 1mnvD-1he3A:
undetectable		 1mnvD-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 166
PRO A 201
THR A 199
 None
 0.86A 1ovfB-1he3A:
undetectable		 1ovfB-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 199
THR A 166
PRO A 201
 None
 0.83A 1qfiB-1he3A:
undetectable		 1qfiB-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		4 / 4 SER A 202
ILE A 176
VAL A 149
THR A 191
 None
 1.12A 1u70A-1he3A:
1.8		 1u70A-1he3A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 199
THR A 166
PRO A 201
 None
 0.85A 1unjF-1he3A:
undetectable		 1unjF-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 166
PRO A 201
THR A 199
 None
 0.85A 1unjL-1he3A:
undetectable		 1unjL-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 199
THR A 166
PRO A 201
 None
 0.85A 1unjL-1he3A:
undetectable		 1unjL-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 199
THR A 166
PRO A 201
 None
 0.84A 1unjR-1he3A:
undetectable		 1unjR-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 166
PRO A 201
THR A 199
 None
 0.86A 1unjX-1he3A:
undetectable		 1unjX-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 199
THR A 166
PRO A 201
 None
 0.84A 1unjX-1he3A:
undetectable		 1unjX-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 166
PRO A 201
THR A 199
 None
 0.86A 1unmE-1he3A:
undetectable		 1unmE-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 199
THR A 166
PRO A 201
 None
 0.82A 1unmE-1he3A:
undetectable		 1unmE-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 166
PRO A 201
THR A 199
 None
 0.85A 1unmF-1he3A:
undetectable		 1unmF-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 199
THR A 166
PRO A 201
 None
 0.81A 1unmF-1he3A:
undetectable		 1unmF-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 166
PRO A 201
THR A 199
 None
 0.77A 209dC-1he3A:
undetectable		 209dC-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 THR A 199
THR A 166
PRO A 201
 None
 0.81A 209dC-1he3A:
undetectable		 209dC-1he3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		4 / 7 LEU A  40
VAL A  32
GLY A  10
ARG A  35
 None
None
NAP  A1206 (-3.1A)
NAP  A1206 (-3.6A)
 0.81A 2wd9A-1he3A:
2.8		 2wd9A-1he3A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		4 / 8 GLY A  16
GLY A  76
LEU A  75
VAL A 149
 None
NAP  A1206 (-3.5A)
NAP  A1206 (-4.6A)
None
 0.62A 3em6A-1he3A:
undetectable		 3em6A-1he3A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		5 / 12 ALA A 108
GLY A  90
ILE A  72
MET A 185
LEU A  74
 None
 1.27A 3gyqA-1he3A:
3.2
3gyqB-1he3A:
3.5		 3gyqA-1he3A:
24.29
3gyqB-1he3A:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 ARG A 140
ASP A 130
GLN A 126
 None
 0.89A 4azsA-1he3A:
5.5		 4azsA-1he3A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		4 / 7 TYR A 163
THR A 199
VAL A 107
VAL A 147
 None
 0.97A 4cp4A-1he3A:
0.0		 4cp4A-1he3A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		4 / 8 THR A  12
LEU A  20
VAL A  32
VAL A  34
 NAP  A1206 (-3.3A)
None
None
None
 0.86A 4em2A-1he3A:
0.0		 4em2A-1he3A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		3 / 3 PHE A 184
VAL A   3
ILE A   6
 None
 0.54A 4emaA-1he3A:
0.0		 4emaA-1he3A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		4 / 8 LEU A  75
ILE A  72
VAL A  65
THR A  64
 NAP  A1206 (-4.6A)
None
None
None
 0.93A 4ma7A-1he3A:
undetectable		 4ma7A-1he3A:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		4 / 7 ALA A 108
GLY A  90
ALA A  91
SER A 142
 None
 0.88A 4r1zB-1he3A:
0.0		 4r1zB-1he3A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		4 / 7 ALA A   7
ASP A  54
GLY A  90
THR A  84
 None
NAP  A1206 (-3.2A)
None
None
 0.95A 5bs8A-1he3A:
0.0
5bs8B-1he3A:
2.7
5bs8C-1he3A:
0.0		 5bs8A-1he3A:
19.33
5bs8B-1he3A:
21.88
5bs8C-1he3A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		4 / 7 ALA A   7
ASP A  54
GLY A  90
THR A  84
 None
NAP  A1206 (-3.2A)
None
None
 0.91A 5btgA-1he3A:
undetectable
5btgC-1he3A:
undetectable
5btgD-1he3A:
2.5		 5btgA-1he3A:
19.33
5btgC-1he3A:
19.33
5btgD-1he3A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 1he3 BILIVERDIN IX BETA
REDUCTASE
(Homo
sapiens) 		4 / 6 TYR A 194
VAL A 107
VAL A 149
THR A 199
 None
 1.46A 6f32B-1he3A:
5.5		 6f32B-1he3A:
17.47