SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1he7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1he7 HIGH AFFINITY NERVE
GROWTH FACTOR
RECEPTOR
(Homo
sapiens) 		5 / 12 GLY A 357
ALA A 376
PHE A 317
LEU A 322
ILE A 301
 None
 1.21A 4hytA-1he7A:
undetectable		 4hytA-1he7A:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1he7 HIGH AFFINITY NERVE
GROWTH FACTOR
RECEPTOR
(Homo
sapiens) 		5 / 12 GLY A 357
ALA A 376
PHE A 317
LEU A 322
ILE A 301
 None
 1.21A 4hytC-1he7A:
undetectable		 4hytC-1he7A:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1he7 HIGH AFFINITY NERVE
GROWTH FACTOR
RECEPTOR
(Homo
sapiens) 		4 / 5 LEU A 348
GLN A 350
PHE A 327
PHE A 317
 None
 1.42A 6nmpP-1he7A:
undetectable
6nmpW-1he7A:
undetectable		 6nmpP-1he7A:
19.37
6nmpW-1he7A:
18.25