SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1heh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1heh ENDO-1,4-BETA-XYLANA
SE D
(Cellulomonas
fimi) 		5 / 12 LEU C 590
PHE C 624
VAL C 588
VAL C 565
ALA C 564
 None
 1.12A 1q23H-1hehC:
undetectable
1q23I-1hehC:
undetectable		 1q23H-1hehC:
15.09
1q23I-1hehC:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 1heh ENDO-1,4-BETA-XYLANA
SE D
(Cellulomonas
fimi) 		4 / 8 VAL C 626
THR C 636
PRO C 637
LEU C 590
 None
 0.86A 1z2bB-1hehC:
undetectable		 1z2bB-1hehC:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1heh ENDO-1,4-BETA-XYLANA
SE D
(Cellulomonas
fimi) 		3 / 4 ARG C 566
GLY C 567
GLU C 569
 None
 0.66A 4z2dB-1hehC:
undetectable
4z2dC-1hehC:
undetectable		 4z2dB-1hehC:
11.90
4z2dC-1hehC:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_B_REAB601_1
(RETINOIC ACID
RECEPTOR)		 1heh ENDO-1,4-BETA-XYLANA
SE D
(Cellulomonas
fimi) 		5 / 10 VAL C 626
SER C 601
PHE C 624
GLY C 638
GLY C 608
 None
 1.14A 6eu9B-1hehC:
undetectable		 6eu9B-1hehC:
19.35