SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hfo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQW_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN)		 1hfo MIGRATION INHIBITORY
FACTOR
(Trichinella
spiralis) 		5 / 12 ILE A  89
VAL A  26
LEU A  83
LEU A  19
ILE A  41
 None
 1.27A 1kqwA-1hfoA:
0.0		 1kqwA-1hfoA:
20.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1hfo MIGRATION INHIBITORY
FACTOR
(Trichinella
spiralis) 		5 / 11 PRO A   1
LYS A  32
SER A  63
ILE A  64
VAL A 106
 None
 0.21A 3rf4A-1hfoA:
19.5
3rf4C-1hfoA:
19.6		 3rf4A-1hfoA:
30.09
3rf4C-1hfoA:
30.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1hfo MIGRATION INHIBITORY
FACTOR
(Trichinella
spiralis) 		5 / 11 PRO A   1
LYS A  32
SER A  63
ILE A  64
VAL A 106
 None
 0.23A 3rf4A-1hfoA:
19.5
3rf4B-1hfoA:
19.6		 3rf4A-1hfoA:
30.09
3rf4B-1hfoA:
30.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1hfo MIGRATION INHIBITORY
FACTOR
(Trichinella
spiralis) 		5 / 11 PRO A   1
LYS A  32
SER A  63
ILE A  64
VAL A 106
 None
 0.25A 3rf4B-1hfoA:
19.6
3rf4C-1hfoA:
19.6		 3rf4B-1hfoA:
30.09
3rf4C-1hfoA:
30.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 1hfo MIGRATION INHIBITORY
FACTOR
(Trichinella
spiralis) 		4 / 7 LEU A  19
ILE A  89
THR A   7
MET A  94
 None
 1.38A 5ljcA-1hfoA:
undetectable		 5ljcA-1hfoA:
20.92