SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hg2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1hg2 CLATHRIN ASSEMBLY
PROTEIN SHORT FORM
(Rattus
norvegicus) 		5 / 9 LEU A  45
ILE A  56
ALA A  60
SER A  62
LEU A  63
 None
 1.16A 1eqgA-1hg2A:
undetectable		 1eqgA-1hg2A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 1hg2 CLATHRIN ASSEMBLY
PROTEIN SHORT FORM
(Rattus
norvegicus) 		3 / 4 LYS A 134
ALA A 135
MET A  86
 None
 1.06A 1hk3A-1hg2A:
undetectable		 1hk3A-1hg2A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 1hg2 CLATHRIN ASSEMBLY
PROTEIN SHORT FORM
(Rattus
norvegicus) 		4 / 7 GLN A 229
GLU A 232
PHE A 145
MET A 159
 None
 1.25A 1linA-1hg2A:
undetectable		 1linA-1hg2A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 1hg2 CLATHRIN ASSEMBLY
PROTEIN SHORT FORM
(Rattus
norvegicus) 		4 / 8 ARG A 150
GLY A 151
ARG A 157
ILE A 216
 None
 0.97A 2f9wA-1hg2A:
undetectable
2f9wB-1hg2A:
undetectable		 2f9wA-1hg2A:
21.36
2f9wB-1hg2A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1hg2 CLATHRIN ASSEMBLY
PROTEIN SHORT FORM
(Rattus
norvegicus) 		3 / 3 LEU A  45
TYR A  44
GLN A  47
 None
 0.62A 2wekA-1hg2A:
undetectable		 2wekA-1hg2A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 1hg2 CLATHRIN ASSEMBLY
PROTEIN SHORT FORM
(Rattus
norvegicus) 		3 / 3 SER A 185
THR A 189
PHE A  76
 None
 0.76A 2x91A-1hg2A:
0.0		 2x91A-1hg2A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_A_4PZA501_1
(CYTOCHROME P450 2E1)		 1hg2 CLATHRIN ASSEMBLY
PROTEIN SHORT FORM
(Rattus
norvegicus) 		3 / 3 ALA A  21
THR A  25
CYH A  48
 None
 0.76A 3e4eA-1hg2A:
undetectable		 3e4eA-1hg2A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_B_4PZB501_1
(CYTOCHROME P450 2E1)		 1hg2 CLATHRIN ASSEMBLY
PROTEIN SHORT FORM
(Rattus
norvegicus) 		3 / 3 ALA A  21
THR A  25
CYH A  48
 None
 0.75A 3e4eB-1hg2A:
undetectable		 3e4eB-1hg2A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1hg2 CLATHRIN ASSEMBLY
PROTEIN SHORT FORM
(Rattus
norvegicus) 		5 / 12 SER A 185
PHE A  76
ILE A 193
ASN A 194
PHE A 123
 None
 1.45A 4c49B-1hg2A:
0.5		 4c49B-1hg2A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1hg2 CLATHRIN ASSEMBLY
PROTEIN SHORT FORM
(Rattus
norvegicus) 		5 / 9 HIS A  83
ILE A 247
GLU A 249
PHE A 250
VAL A 253
 None
 1.31A 5igzA-1hg2A:
undetectable		 5igzA-1hg2A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1hg2 CLATHRIN ASSEMBLY
PROTEIN SHORT FORM
(Rattus
norvegicus) 		5 / 12 ASP A 111
GLY A 117
MET A 120
ASN A 190
PHE A 181
 None
 1.44A 5kc4A-1hg2A:
0.5		 5kc4A-1hg2A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 1hg2 CLATHRIN ASSEMBLY
PROTEIN SHORT FORM
(Rattus
norvegicus) 		4 / 7 PHE A 143
ALA A 210
GLY A 214
TYR A 211
 None
 0.91A 5uxdA-1hg2A:
undetectable		 5uxdA-1hg2A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 1hg2 CLATHRIN ASSEMBLY
PROTEIN SHORT FORM
(Rattus
norvegicus) 		4 / 7 GLY A  89
GLN A 174
TYR A 130
ASP A 144
 None
 1.18A 5vlmG-1hg2A:
3.1		 5vlmG-1hg2A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 1hg2 CLATHRIN ASSEMBLY
PROTEIN SHORT FORM
(Rattus
norvegicus) 		5 / 12 VAL A  26
LEU A  63
ALA A  29
LEU A  85
LEU A  59
 None
 1.12A 6f6iA-1hg2A:
undetectable
6f6iB-1hg2A:
undetectable		 6f6iA-1hg2A:
13.94
6f6iB-1hg2A:
14.48