SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hg4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		6 / 12 TRP A 318
LEU A 322
ILE A 385
LEU A 476
LEU A 487
LEU A 490
 None
LPP  A   1 ( 4.8A)
None
LPP  A   1 (-4.2A)
None
None
 0.89A 1errB-1hg4A:
24.1		 1errB-1hg4A:
27.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 366
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.4A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.76A 1fm6A-1hg4A:
24.0		 1fm6A-1hg4A:
44.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 LEU A 366
VAL A 382
CYH A 472
HIS A 475
LEU A 476
 LPP  A   1 ( 4.4A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
None
LPP  A   1 (-4.2A)
 0.66A 1fm6U-1hg4A:
24.3		 1fm6U-1hg4A:
44.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		6 / 12 TRP A 318
VAL A 382
ILE A 385
CYH A 472
HIS A 475
LEU A 476
 None
LPP  A   1 (-4.8A)
None
LPP  A   1 ( 4.2A)
None
LPP  A   1 (-4.2A)
 1.14A 1fm6U-1hg4A:
24.3		 1fm6U-1hg4A:
44.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 322
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.8A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.62A 1fm9A-1hg4A:
24.1		 1fm9A-1hg4A:
44.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 366
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.4A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.75A 1fm9A-1hg4A:
24.1		 1fm9A-1hg4A:
44.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 322
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.8A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.67A 1k74A-1hg4A:
24.2		 1k74A-1hg4A:
44.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 366
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.4A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.80A 1k74A-1hg4A:
24.2		 1k74A-1hg4A:
44.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		4 / 4 LEU A 321
ILE A 240
ARG A 405
TYR A 416
 None
 1.42A 1rk3A-1hg4A:
19.2		 1rk3A-1hg4A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		4 / 7 TYR A 295
GLU A 247
TYR A 416
ILE A 240
 None
 1.20A 1tuvA-1hg4A:
undetectable		 1tuvA-1hg4A:
18.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 366
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.4A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.71A 1xdkA-1hg4A:
24.7		 1xdkA-1hg4A:
43.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 366
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.4A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.71A 1xdkE-1hg4A:
24.7		 1xdkE-1hg4A:
43.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 LEU A 322
VAL A 382
CYH A 472
HIS A 475
LEU A 476
 LPP  A   1 ( 4.8A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
None
LPP  A   1 (-4.2A)
 0.46A 1xiuB-1hg4A:
24.2		 1xiuB-1hg4A:
41.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 322
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.8A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.50A 1xlsA-1hg4A:
24.0		 1xlsA-1hg4A:
45.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 366
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.4A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.65A 1xlsA-1hg4A:
24.0		 1xlsA-1hg4A:
45.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 322
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.8A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.51A 1xlsB-1hg4A:
24.0		 1xlsB-1hg4A:
45.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 366
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.4A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.65A 1xlsB-1hg4A:
24.0		 1xlsB-1hg4A:
45.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 322
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.8A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.50A 1xlsC-1hg4A:
24.0		 1xlsC-1hg4A:
45.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 366
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.4A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.65A 1xlsC-1hg4A:
24.0		 1xlsC-1hg4A:
45.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 322
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.8A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.49A 1xlsD-1hg4A:
24.0		 1xlsD-1hg4A:
45.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 366
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.4A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.65A 1xlsD-1hg4A:
24.0		 1xlsD-1hg4A:
45.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		4 / 7 LEU A 410
ILE A 240
ARG A 405
TYR A 416
 None
 1.18A 2hc4A-1hg4A:
19.2		 2hc4A-1hg4A:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		4 / 5 LEU A 321
ILE A 240
ARG A 405
TYR A 416
 None
 1.45A 2zlcA-1hg4A:
19.1		 2zlcA-1hg4A:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 ILE A 323
LEU A 366
VAL A 382
HIS A 475
LEU A 476
 None
LPP  A   1 ( 4.4A)
LPP  A   1 (-4.8A)
None
LPP  A   1 (-4.2A)
 0.79A 3dzuA-1hg4A:
24.4		 3dzuA-1hg4A:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 ILE A 323
VAL A 382
CYH A 472
HIS A 475
LEU A 476
 None
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
None
LPP  A   1 (-4.2A)
 0.51A 3dzuA-1hg4A:
24.4		 3dzuA-1hg4A:
26.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 322
VAL A 382
ILE A 385
LEU A 476
 None
LPP  A   1 ( 4.8A)
LPP  A   1 (-4.8A)
None
LPP  A   1 (-4.2A)
 0.74A 3h0aA-1hg4A:
23.1		 3h0aA-1hg4A:
42.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 366
VAL A 382
ILE A 385
LEU A 476
 None
LPP  A   1 ( 4.4A)
LPP  A   1 (-4.8A)
None
LPP  A   1 (-4.2A)
 0.78A 3h0aA-1hg4A:
23.1		 3h0aA-1hg4A:
42.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		3 / 3 MET A 298
CYH A 254
PRO A 499
 None
 0.95A 3h52C-1hg4A:
19.0		 3h52C-1hg4A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		4 / 5 LEU A 490
ARG A 263
LEU A 487
PRO A 486
 None
 1.34A 3onnA-1hg4A:
undetectable		 3onnA-1hg4A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		4 / 7 ASN A 417
ALA A 316
ARG A 421
ARG A 426
 None
 1.07A 3twpA-1hg4A:
undetectable		 3twpA-1hg4A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		4 / 7 ASN A 417
ALA A 316
ARG A 421
ARG A 426
 None
 0.99A 3twpB-1hg4A:
undetectable		 3twpB-1hg4A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		4 / 7 ASN A 417
ALA A 316
ARG A 421
ARG A 426
 None
 1.13A 3twpC-1hg4A:
undetectable		 3twpC-1hg4A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 ILE A 481
THR A 482
PHE A 491
LEU A 476
ILE A 323
 None
None
None
LPP  A   1 (-4.2A)
None
 0.99A 4g1bD-1hg4A:
undetectable		 4g1bD-1hg4A:
20.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 11 TRP A 318
LEU A 322
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.8A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.51A 5ji0A-1hg4A:
24.3		 5ji0A-1hg4A:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 11 TRP A 318
LEU A 366
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.4A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.74A 5ji0A-1hg4A:
24.3		 5ji0A-1hg4A:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 366
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.4A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.81A 5uanA-1hg4A:
24.3		 5uanA-1hg4A:
32.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 322
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.8A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.59A 5z12B-1hg4A:
24.7		 5z12B-1hg4A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 366
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.4A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.67A 5z12B-1hg4A:
24.7		 5z12B-1hg4A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 366
VAL A 382
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.4A)
LPP  A   1 (-4.8A)
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.71A 5z12C-1hg4A:
24.3		 5z12C-1hg4A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 TRP A 318
LEU A 366
ILE A 385
CYH A 472
LEU A 476
 None
LPP  A   1 ( 4.4A)
None
LPP  A   1 ( 4.2A)
LPP  A   1 (-4.2A)
 0.74A 6a5yD-1hg4A:
25.0		 6a5yD-1hg4A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 LEU A 366
ILE A 385
CYH A 472
HIS A 475
LEU A 476
 LPP  A   1 ( 4.4A)
None
LPP  A   1 ( 4.2A)
None
LPP  A   1 (-4.2A)
 0.74A 6a5zL-1hg4A:
24.9		 6a5zL-1hg4A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1hg4 ULTRASPIRACLE
(Drosophila
melanogaster) 		5 / 12 LEU A 322
ILE A 385
CYH A 472
HIS A 475
LEU A 476
 LPP  A   1 ( 4.8A)
None
LPP  A   1 ( 4.2A)
None
LPP  A   1 (-4.2A)
 0.55A 6a60D-1hg4A:
24.7		 6a60D-1hg4A:
17.94