SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hi9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		4 / 8 ALA A 232
GLY A 120
THR A 271
ILE A 118
 None
 0.72A 1gtnI-1hi9A:
0.4
1gtnJ-1hi9A:
0.2		 1gtnI-1hi9A:
15.08
1gtnJ-1hi9A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		4 / 8 GLY A 102
VAL A   7
MET A   5
ILE A  12
 None
 0.79A 1pk7B-1hi9A:
undetectable		 1pk7B-1hi9A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		5 / 12 GLY A 120
THR A 271
ILE A 118
GLY A 227
ALA A 232
 None
 0.94A 1utdL-1hi9A:
undetectable
1utdM-1hi9A:
0.3		 1utdL-1hi9A:
15.08
1utdM-1hi9A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		5 / 12 GLY A 120
THR A 271
ILE A 118
GLY A 227
ALA A 232
 None
 0.95A 1utdO-1hi9A:
undetectable
1utdP-1hi9A:
0.0		 1utdO-1hi9A:
15.08
1utdP-1hi9A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		5 / 11 GLY A 120
THR A 271
ILE A 118
GLY A 227
ALA A 232
 None
 0.97A 1utdP-1hi9A:
0.0
1utdQ-1hi9A:
0.4		 1utdP-1hi9A:
15.08
1utdQ-1hi9A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		6 / 8 GLU A  10
HIS A 104
ASP A   8
HIS A  60
HIS A 115
GLU A 133
 ZN  A 301 (-2.3A)
ZN  A 300 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 301 (-3.6A)
ZN  A 300 (-4.4A)
ZN  A 300 (-2.1A)
 0.78A 1v7zA-1hi9A:
4.0		 1v7zA-1hi9A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		6 / 8 GLU A  10
HIS A 104
ASP A   8
HIS A  60
HIS A 115
GLU A 133
 ZN  A 301 (-2.3A)
ZN  A 300 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 301 (-3.6A)
ZN  A 300 (-4.4A)
ZN  A 300 (-2.1A)
 0.78A 1v7zB-1hi9A:
4.0		 1v7zB-1hi9A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		6 / 8 GLU A  10
HIS A 104
ASP A   8
HIS A  60
HIS A 115
GLU A 133
 ZN  A 301 (-2.3A)
ZN  A 300 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 301 (-3.6A)
ZN  A 300 (-4.4A)
ZN  A 300 (-2.1A)
 0.78A 1v7zC-1hi9A:
4.2		 1v7zC-1hi9A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		6 / 8 GLU A  10
HIS A 104
ASP A   8
HIS A  60
HIS A 115
GLU A 133
 ZN  A 301 (-2.3A)
ZN  A 300 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 301 (-3.6A)
ZN  A 300 (-4.4A)
ZN  A 300 (-2.1A)
 0.78A 1v7zD-1hi9A:
4.0		 1v7zD-1hi9A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		6 / 8 GLU A  10
HIS A 104
ASP A   8
HIS A  60
HIS A 115
GLU A 133
 ZN  A 301 (-2.3A)
ZN  A 300 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 301 (-3.6A)
ZN  A 300 (-4.4A)
ZN  A 300 (-2.1A)
 0.79A 1v7zE-1hi9A:
4.1		 1v7zE-1hi9A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		6 / 8 GLU A  10
HIS A 104
ASP A   8
HIS A  60
HIS A 115
GLU A 133
 ZN  A 301 (-2.3A)
ZN  A 300 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 301 (-3.6A)
ZN  A 300 (-4.4A)
ZN  A 300 (-2.1A)
 0.78A 1v7zF-1hi9A:
4.1		 1v7zF-1hi9A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		5 / 10 GLY A 132
LEU A 136
LEU A 134
PHE A 100
TYR A 258
 None
 0.99A 2f8dA-1hi9A:
1.0		 2f8dA-1hi9A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		5 / 10 GLY A 132
LEU A 136
LEU A 134
PHE A 100
TYR A 258
 None
 0.99A 2f8dB-1hi9A:
1.0		 2f8dB-1hi9A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		6 / 8 GLU A  10
HIS A 104
ASP A   8
HIS A  60
HIS A 115
GLU A 133
 ZN  A 301 (-2.3A)
ZN  A 300 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 301 (-3.6A)
ZN  A 300 (-4.4A)
ZN  A 300 (-2.1A)
 0.81A 3a6jA-1hi9A:
4.1		 3a6jA-1hi9A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		6 / 7 GLU A  10
HIS A 104
ASP A   8
HIS A  60
HIS A 115
GLU A 133
 ZN  A 301 (-2.3A)
ZN  A 300 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 301 (-3.6A)
ZN  A 300 (-4.4A)
ZN  A 300 (-2.1A)
 0.82A 3a6jB-1hi9A:
4.1		 3a6jB-1hi9A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		6 / 8 GLU A  10
HIS A 104
ASP A   8
HIS A  60
HIS A 115
GLU A 133
 ZN  A 301 (-2.3A)
ZN  A 300 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 301 (-3.6A)
ZN  A 300 (-4.4A)
ZN  A 300 (-2.1A)
 0.80A 3a6jC-1hi9A:
3.9		 3a6jC-1hi9A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		6 / 8 GLU A  10
HIS A 104
ASP A   8
HIS A  60
HIS A 115
GLU A 133
 ZN  A 301 (-2.3A)
ZN  A 300 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 301 (-3.6A)
ZN  A 300 (-4.4A)
ZN  A 300 (-2.1A)
 0.82A 3a6jE-1hi9A:
4.0		 3a6jE-1hi9A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		6 / 8 GLU A  10
HIS A 104
ASP A   8
HIS A  60
HIS A 115
GLU A 133
 ZN  A 301 (-2.3A)
ZN  A 300 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 301 (-3.6A)
ZN  A 300 (-4.4A)
ZN  A 300 (-2.1A)
 0.80A 3a6jF-1hi9A:
4.5		 3a6jF-1hi9A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		4 / 4 LEU A  33
ARG A 190
ILE A  34
ILE A  12
 None
 1.19A 5dzk2-1hi9A:
undetectable
5dzkM-1hi9A:
0.9
5dzkN-1hi9A:
0.8		 5dzk2-1hi9A:
1.03
5dzkM-1hi9A:
21.71
5dzkN-1hi9A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		4 / 4 ILE A  34
ILE A  12
ARG A 190
LEU A  33
 None
 1.39A 5dzkh-1hi9A:
0.6
5dzkn-1hi9A:
0.8
5dzkv-1hi9A:
undetectable		 5dzkh-1hi9A:
21.71
5dzkn-1hi9A:
21.71
5dzkv-1hi9A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		5 / 10 LEU A  99
SER A  59
THR A 170
GLY A 135
LEU A 134
 None
 1.13A 5m5cE-1hi9A:
4.3		 5m5cE-1hi9A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 1hi9 DIPEPTIDE TRANSPORT
PROTEIN DPPA
(Bacillus
subtilis) 		3 / 3 PHE A  20
ASP A  22
LYS A  25
 None
 0.89A 6awtD-1hi9A:
0.0		 6awtD-1hi9A:
21.30