SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hkf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 1hkf NK CELL ACTIVATING
RECEPTOR
(Homo
sapiens) 		3 / 3 TYR A  24
GLU A  32
ASN A  99
 None
 1.01A 2y7hC-1hkfA:
undetectable		 2y7hC-1hkfA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 1hkf NK CELL ACTIVATING
RECEPTOR
(Homo
sapiens) 		5 / 11 ILE A  65
THR A  64
PHE A  63
VAL A  20
TYR A  89
 None
 1.13A 4g1bB-1hkfA:
undetectable		 4g1bB-1hkfA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 1hkf NK CELL ACTIVATING
RECEPTOR
(Homo
sapiens) 		5 / 12 ILE A  65
THR A  64
PHE A  63
VAL A  20
TYR A  89
 None
 1.13A 4g1bD-1hkfA:
undetectable		 4g1bD-1hkfA:
11.94