SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hlm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1hlm HEMOGLOBIN (CYANO
MET)
(Molpadia
arenicola) 		4 / 8 TYR A 114
GLY A 150
LEU A  97
PHE A 145
 HEM  A 159 ( 4.9A)
None
None
None
 1.09A 1gsfA-1hlmA:
undetectable		 1gsfA-1hlmA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1hlm HEMOGLOBIN (CYANO
MET)
(Molpadia
arenicola) 		4 / 8 TYR A 114
GLY A 150
LEU A  97
PHE A 145
 HEM  A 159 ( 4.9A)
None
None
None
 1.09A 1gsfB-1hlmA:
undetectable		 1gsfB-1hlmA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1hlm HEMOGLOBIN (CYANO
MET)
(Molpadia
arenicola) 		4 / 8 TYR A 114
GLY A 150
LEU A  97
PHE A 145
 HEM  A 159 ( 4.9A)
None
None
None
 1.09A 1gsfD-1hlmA:
undetectable		 1gsfD-1hlmA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 1hlm HEMOGLOBIN (CYANO
MET)
(Molpadia
arenicola) 		4 / 7 PHE A 133
ALA A 127
GLU A 128
LEU A 129
 None
 0.94A 1hk2A-1hlmA:
0.0		 1hk2A-1hlmA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1hlm HEMOGLOBIN (CYANO
MET)
(Molpadia
arenicola) 		4 / 6 LEU A 121
ARG A  31
MET A  81
THR A  82
 None
None
HEM  A 159 ( 4.3A)
None
 1.05A 1v54A-1hlmA:
0.0
1v54J-1hlmA:
0.0		 1v54A-1hlmA:
16.39
1v54J-1hlmA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1hlm HEMOGLOBIN (CYANO
MET)
(Molpadia
arenicola) 		4 / 6 LEU A 121
ARG A  31
MET A  81
THR A  82
 None
None
HEM  A 159 ( 4.3A)
None
 1.05A 2dyrA-1hlmA:
0.0
2dyrJ-1hlmA:
undetectable		 2dyrA-1hlmA:
16.39
2dyrJ-1hlmA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1hlm HEMOGLOBIN (CYANO
MET)
(Molpadia
arenicola) 		4 / 6 LEU A 121
ARG A  31
MET A  81
THR A  82
 None
None
HEM  A 159 ( 4.3A)
None
 1.05A 2dysA-1hlmA:
undetectable
2dysJ-1hlmA:
undetectable		 2dysA-1hlmA:
16.39
2dysJ-1hlmA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1hlm HEMOGLOBIN (CYANO
MET)
(Molpadia
arenicola) 		4 / 6 LEU A 121
ARG A  31
MET A  81
THR A  82
 None
None
HEM  A 159 ( 4.3A)
None
 1.04A 2eijA-1hlmA:
0.0
2eijJ-1hlmA:
0.0		 2eijA-1hlmA:
16.39
2eijJ-1hlmA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1hlm HEMOGLOBIN (CYANO
MET)
(Molpadia
arenicola) 		4 / 6 LEU A 121
ARG A  31
MET A  81
THR A  82
 None
None
HEM  A 159 ( 4.3A)
None
 1.05A 2eilA-1hlmA:
undetectable
2eilJ-1hlmA:
0.0		 2eilA-1hlmA:
16.39
2eilJ-1hlmA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1hlm HEMOGLOBIN (CYANO
MET)
(Molpadia
arenicola) 		5 / 7 LEU A  12
GLU A  16
ILE A  20
GLN A  26
ALA A 127
 None
 1.42A 2xkwA-1hlmA:
undetectable		 2xkwA-1hlmA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1hlm HEMOGLOBIN (CYANO
MET)
(Molpadia
arenicola) 		4 / 6 LEU A 121
ARG A  31
MET A  81
THR A  82
 None
None
HEM  A 159 ( 4.3A)
None
 1.06A 2zxwA-1hlmA:
undetectable
2zxwJ-1hlmA:
undetectable		 2zxwA-1hlmA:
16.39
2zxwJ-1hlmA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1hlm HEMOGLOBIN (CYANO
MET)
(Molpadia
arenicola) 		4 / 6 LEU A 121
ARG A  31
MET A  81
THR A  82
 None
None
HEM  A 159 ( 4.3A)
None
 1.09A 3asnA-1hlmA:
undetectable
3asnJ-1hlmA:
undetectable		 3asnA-1hlmA:
16.39
3asnJ-1hlmA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1hlm HEMOGLOBIN (CYANO
MET)
(Molpadia
arenicola) 		5 / 9 TRP A 141
PHE A 117
ALA A 124
LEU A 121
GLY A 118
 None
HEM  A 159 (-3.7A)
None
None
None
 1.41A 3lw5A-1hlmA:
1.2		 3lw5A-1hlmA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1hlm HEMOGLOBIN (CYANO
MET)
(Molpadia
arenicola) 		4 / 5 GLU A  63
LEU A  59
GLN A  50
GLY A  58
 None
 1.09A 3pp1A-1hlmA:
undetectable		 3pp1A-1hlmA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 1hlm HEMOGLOBIN (CYANO
MET)
(Molpadia
arenicola) 		4 / 7 PHE A  53
VAL A 109
PHE A  39
ASN A 113
 HEM  A 159 (-4.4A)
HEM  A 159 (-3.7A)
CYN  A 160 (-4.7A)
HEM  A 159 ( 4.1A)
 0.95A 4ejjB-1hlmA:
undetectable		 4ejjB-1hlmA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 1hlm HEMOGLOBIN (CYANO
MET)
(Molpadia
arenicola) 		4 / 7 GLN A 149
LEU A  97
THR A 101
THR A  82
 None
 1.13A 4mbsA-1hlmA:
0.0		 4mbsA-1hlmA:
16.07