SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hmd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 8 GLU A  58
ASP A 106
HIS A  73
TRP A  97
HIS A  54
 FEO  A 115 (-2.5A)
FEO  A 115 (-2.6A)
FEO  A 115 (-3.4A)
None
FEO  A 115 (-3.5A)
 1.29A 1v7zA-1hmdA:
undetectable		 1v7zA-1hmdA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 8 GLU A  58
ASP A 106
HIS A  73
TRP A  97
HIS A  54
 FEO  A 115 (-2.5A)
FEO  A 115 (-2.6A)
FEO  A 115 (-3.4A)
None
FEO  A 115 (-3.5A)
 1.31A 1v7zB-1hmdA:
undetectable		 1v7zB-1hmdA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 8 GLU A  58
ASP A 106
HIS A  73
TRP A  97
HIS A  54
 FEO  A 115 (-2.5A)
FEO  A 115 (-2.6A)
FEO  A 115 (-3.4A)
None
FEO  A 115 (-3.5A)
 1.34A 1v7zC-1hmdA:
undetectable		 1v7zC-1hmdA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 8 GLU A  58
ASP A 106
HIS A  73
TRP A  97
HIS A  54
 FEO  A 115 (-2.5A)
FEO  A 115 (-2.6A)
FEO  A 115 (-3.4A)
None
FEO  A 115 (-3.5A)
 1.29A 1v7zD-1hmdA:
undetectable		 1v7zD-1hmdA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 8 GLU A  58
ASP A 106
HIS A  73
TRP A  97
HIS A  54
 FEO  A 115 (-2.5A)
FEO  A 115 (-2.6A)
FEO  A 115 (-3.4A)
None
FEO  A 115 (-3.5A)
 1.29A 1v7zE-1hmdA:
undetectable		 1v7zE-1hmdA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 8 GLU A  58
ASP A 106
HIS A  73
TRP A  97
HIS A  54
 FEO  A 115 (-2.5A)
FEO  A 115 (-2.6A)
FEO  A 115 (-3.4A)
None
FEO  A 115 (-3.5A)
 1.33A 1v7zF-1hmdA:
undetectable		 1v7zF-1hmdA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 6 ILE A  21
HIS A  73
HIS A  77
HIS A 101
 None
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 0.95A 1y93A-1hmdA:
undetectable		 1y93A-1hmdA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 6 ILE A  21
HIS A  77
HIS A 101
HIS A  73
 None
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 0.73A 1y93A-1hmdA:
undetectable		 1y93A-1hmdA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 6 ILE A  21
HIS A 101
HIS A  73
HIS A  77
 None
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 0.90A 1y93A-1hmdA:
undetectable		 1y93A-1hmdA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 8 HIS A 101
ASP A 106
ILE A  21
HIS A  77
 FEO  A 115 (-3.4A)
FEO  A 115 (-2.6A)
None
FEO  A 115 (-3.4A)
 0.88A 2xadA-1hmdA:
undetectable		 2xadA-1hmdA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 8 HIS A 101
ASP A 106
ILE A  21
HIS A  77
 FEO  A 115 (-3.4A)
FEO  A 115 (-2.6A)
None
FEO  A 115 (-3.4A)
 0.93A 2xadB-1hmdA:
undetectable		 2xadB-1hmdA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 8 HIS A 101
ASP A 106
ILE A  21
HIS A  77
 FEO  A 115 (-3.4A)
FEO  A 115 (-2.6A)
None
FEO  A 115 (-3.4A)
 0.86A 2xadC-1hmdA:
undetectable		 2xadC-1hmdA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 8 HIS A 101
ASP A 106
ILE A  21
HIS A  77
 FEO  A 115 (-3.4A)
FEO  A 115 (-2.6A)
None
FEO  A 115 (-3.4A)
 0.90A 2xadD-1hmdA:
undetectable		 2xadD-1hmdA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  25
HIS A  54
HIS A  73
HIS A 101
ASP A  79
 FEO  A 115 (-3.3A)
FEO  A 115 (-3.5A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
None
 1.42A 2zweA-1hmdA:
undetectable
2zweB-1hmdA:
undetectable		 2zweA-1hmdA:
14.70
2zweB-1hmdA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  54
ILE A  21
HIS A  25
HIS A 101
HIS A  77
 FEO  A 115 (-3.5A)
None
FEO  A 115 (-3.3A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 1.39A 2zweA-1hmdA:
undetectable
2zweB-1hmdA:
undetectable		 2zweA-1hmdA:
14.70
2zweB-1hmdA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  54
ILE A  21
HIS A  25
HIS A 101
HIS A  77
 FEO  A 115 (-3.5A)
None
FEO  A 115 (-3.3A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 1.35A 2zwfA-1hmdA:
undetectable
2zwfB-1hmdA:
undetectable		 2zwfA-1hmdA:
14.70
2zwfB-1hmdA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  54
ILE A  21
HIS A  25
HIS A 101
HIS A  77
 FEO  A 115 (-3.5A)
None
FEO  A 115 (-3.3A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 1.35A 2zwgA-1hmdA:
undetectable
2zwgB-1hmdA:
undetectable		 2zwgA-1hmdA:
14.70
2zwgB-1hmdA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 8 GLU A  58
ASP A 106
HIS A  73
TRP A  97
HIS A  54
 FEO  A 115 (-2.5A)
FEO  A 115 (-2.6A)
FEO  A 115 (-3.4A)
None
FEO  A 115 (-3.5A)
 1.28A 3a6jA-1hmdA:
undetectable		 3a6jA-1hmdA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 8 GLU A  58
ASP A 106
HIS A  73
TRP A  97
HIS A  54
 FEO  A 115 (-2.5A)
FEO  A 115 (-2.6A)
FEO  A 115 (-3.4A)
None
FEO  A 115 (-3.5A)
 1.29A 3a6jC-1hmdA:
undetectable		 3a6jC-1hmdA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 8 GLU A  58
ASP A 106
HIS A  73
TRP A  97
HIS A  54
 FEO  A 115 (-2.5A)
FEO  A 115 (-2.6A)
FEO  A 115 (-3.4A)
None
FEO  A 115 (-3.5A)
 1.27A 3a6jE-1hmdA:
undetectable		 3a6jE-1hmdA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 8 GLU A  58
ASP A 106
HIS A  73
TRP A  97
HIS A  54
 FEO  A 115 (-2.5A)
FEO  A 115 (-2.6A)
FEO  A 115 (-3.4A)
None
FEO  A 115 (-3.5A)
 1.30A 3a6jF-1hmdA:
undetectable		 3a6jF-1hmdA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 7 HIS A  73
HIS A 101
HIS A  25
HIS A  54
 FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.3A)
FEO  A 115 (-3.5A)
 0.81A 4p6sA-1hmdA:
undetectable		 4p6sA-1hmdA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 7 HIS A  73
HIS A 101
HIS A  25
HIS A  54
 FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.3A)
FEO  A 115 (-3.5A)
 0.79A 4p6sB-1hmdA:
undetectable		 4p6sB-1hmdA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 7 HIS A  73
HIS A 101
HIS A  25
HIS A  54
 FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.3A)
FEO  A 115 (-3.5A)
 0.82A 5i3aA-1hmdA:
undetectable		 5i3aA-1hmdA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 7 HIS A  73
HIS A 101
HIS A  25
HIS A  54
 FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.3A)
FEO  A 115 (-3.5A)
 0.80A 5i3aB-1hmdA:
undetectable		 5i3aB-1hmdA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 7 HIS A  73
HIS A 101
HIS A  25
HIS A  54
 FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.3A)
FEO  A 115 (-3.5A)
 0.89A 5i3bA-1hmdA:
undetectable		 5i3bA-1hmdA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 5 ILE A  21
HIS A  73
HIS A  77
HIS A 101
 None
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 1.00A 5n5kA-1hmdA:
undetectable		 5n5kA-1hmdA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 5 ILE A  21
HIS A  77
HIS A 101
HIS A  73
 None
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 0.75A 5n5kA-1hmdA:
undetectable		 5n5kA-1hmdA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 5 ILE A  21
HIS A 101
HIS A  73
HIS A  77
 None
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 0.92A 5n5kA-1hmdA:
undetectable		 5n5kA-1hmdA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PAH_A_LDPA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 4 HIS A  54
HIS A  25
TYR A 109
GLU A  58
 FEO  A 115 (-3.5A)
FEO  A 115 (-3.3A)
None
FEO  A 115 (-2.5A)
 1.20A 5pahA-1hmdA:
undetectable		 5pahA-1hmdA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  25
HIS A  54
HIS A  73
HIS A 101
ASP A  79
 FEO  A 115 (-3.3A)
FEO  A 115 (-3.5A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
None
 1.36A 5z0fA-1hmdA:
undetectable
5z0fB-1hmdA:
undetectable		 5z0fA-1hmdA:
20.69
5z0fB-1hmdA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  54
ILE A  21
HIS A  25
HIS A 101
HIS A  73
 FEO  A 115 (-3.5A)
None
FEO  A 115 (-3.3A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 1.34A 5z0fA-1hmdA:
undetectable
5z0fB-1hmdA:
undetectable		 5z0fA-1hmdA:
20.69
5z0fB-1hmdA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  54
ILE A  21
HIS A  25
HIS A 101
HIS A  77
 FEO  A 115 (-3.5A)
None
FEO  A 115 (-3.3A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 1.38A 5z0fA-1hmdA:
undetectable
5z0fB-1hmdA:
undetectable		 5z0fA-1hmdA:
20.69
5z0fB-1hmdA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  25
HIS A  54
HIS A  73
HIS A 101
ASP A  79
 FEO  A 115 (-3.3A)
FEO  A 115 (-3.5A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
None
 1.41A 5z0gA-1hmdA:
undetectable
5z0gB-1hmdA:
undetectable		 5z0gA-1hmdA:
20.69
5z0gB-1hmdA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  54
ILE A  21
HIS A  25
HIS A 101
HIS A  73
 FEO  A 115 (-3.5A)
None
FEO  A 115 (-3.3A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 1.33A 5z0gA-1hmdA:
undetectable
5z0gB-1hmdA:
undetectable		 5z0gA-1hmdA:
20.69
5z0gB-1hmdA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  54
ILE A  21
HIS A  25
HIS A 101
HIS A  77
 FEO  A 115 (-3.5A)
None
FEO  A 115 (-3.3A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 1.37A 5z0gA-1hmdA:
undetectable
5z0gB-1hmdA:
undetectable		 5z0gA-1hmdA:
20.69
5z0gB-1hmdA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  54
ILE A  21
HIS A  25
HIS A 101
HIS A  77
 FEO  A 115 (-3.5A)
None
FEO  A 115 (-3.3A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 1.35A 5z0hA-1hmdA:
undetectable
5z0hB-1hmdA:
undetectable		 5z0hA-1hmdA:
20.69
5z0hB-1hmdA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  25
HIS A  54
HIS A  73
HIS A 101
ASP A  79
 FEO  A 115 (-3.3A)
FEO  A 115 (-3.5A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
None
 1.47A 5z0iA-1hmdA:
undetectable
5z0iB-1hmdA:
undetectable		 5z0iA-1hmdA:
20.69
5z0iB-1hmdA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  54
ILE A  21
HIS A  25
HIS A 101
HIS A  73
 FEO  A 115 (-3.5A)
None
FEO  A 115 (-3.3A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 1.34A 5z0iA-1hmdA:
undetectable
5z0iB-1hmdA:
undetectable		 5z0iA-1hmdA:
20.69
5z0iB-1hmdA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  54
ILE A  21
HIS A  25
HIS A 101
HIS A  77
 FEO  A 115 (-3.5A)
None
FEO  A 115 (-3.3A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 1.36A 5z0iA-1hmdA:
undetectable
5z0iB-1hmdA:
undetectable		 5z0iA-1hmdA:
20.69
5z0iB-1hmdA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  25
HIS A  54
HIS A  73
HIS A 101
ASP A  79
 FEO  A 115 (-3.3A)
FEO  A 115 (-3.5A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
None
 1.41A 5z0jA-1hmdA:
undetectable
5z0jB-1hmdA:
undetectable		 5z0jA-1hmdA:
20.69
5z0jB-1hmdA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  54
ILE A  21
HIS A  25
HIS A 101
HIS A  77
 FEO  A 115 (-3.5A)
None
FEO  A 115 (-3.3A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 1.39A 5z0jA-1hmdA:
undetectable
5z0jB-1hmdA:
undetectable		 5z0jA-1hmdA:
20.69
5z0jB-1hmdA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  25
HIS A  54
HIS A  73
HIS A 101
ASP A  79
 FEO  A 115 (-3.3A)
FEO  A 115 (-3.5A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
None
 1.45A 5z0kA-1hmdA:
undetectable
5z0kB-1hmdA:
undetectable		 5z0kA-1hmdA:
20.69
5z0kB-1hmdA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  54
ILE A  21
HIS A  25
HIS A 101
HIS A  77
 FEO  A 115 (-3.5A)
None
FEO  A 115 (-3.3A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 1.37A 5z0kA-1hmdA:
undetectable
5z0kB-1hmdA:
undetectable		 5z0kA-1hmdA:
20.69
5z0kB-1hmdA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  54
ILE A  21
HIS A  25
HIS A 101
HIS A  77
 FEO  A 115 (-3.5A)
None
FEO  A 115 (-3.3A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 1.34A 5z0lA-1hmdA:
undetectable
5z0lB-1hmdA:
undetectable		 5z0lA-1hmdA:
20.69
5z0lB-1hmdA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		5 / 11 HIS A  54
ILE A  21
HIS A  25
HIS A 101
HIS A  77
 FEO  A 115 (-3.5A)
None
FEO  A 115 (-3.3A)
FEO  A 115 (-3.4A)
FEO  A 115 (-3.4A)
 1.34A 5z0mA-1hmdA:
undetectable
5z0mB-1hmdA:
undetectable		 5z0mA-1hmdA:
19.83
5z0mB-1hmdA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1hmd HEMERYTHRIN
(Themiste
dyscritum) 		4 / 6 TRP A  97
LEU A  56
ASP A 106
GLU A  58
 None
None
FEO  A 115 (-2.6A)
FEO  A 115 (-2.5A)
 1.39A 6djzC-1hmdA:
undetectable		 6djzC-1hmdA:
19.13