SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hn0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY5_A_ACTA600_0
(RIBONUCLEASE A)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 4 HIS A 475
VAL A 470
ASN A 471
THR A 472
 None
 1.21A 1dy5A-1hn0A:
undetectable		 1dy5A-1hn0A:
8.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 7 ARG A 212
TYR A  42
PHE A  44
PHE A  53
 None
 1.25A 1e71M-1hn0A:
undetectable		 1e71M-1hn0A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 7 ILE A 547
ARG A 634
TYR A 548
PHE A 510
 None
 1.23A 1e71M-1hn0A:
undetectable		 1e71M-1hn0A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 7 ILE A 547
ARG A 634
TYR A 548
PHE A 510
 None
 1.20A 1e72M-1hn0A:
undetectable		 1e72M-1hn0A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 6 ILE A 547
ARG A 634
TYR A 548
PHE A 510
 None
 1.22A 1e73M-1hn0A:
undetectable		 1e73M-1hn0A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 6 PHE A 722
ILE A 975
ALA A 923
MET A 734
 None
 1.20A 1hk2A-1hn0A:
2.3		 1hk2A-1hn0A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 ASP A 914
LEU A 765
LEU A 759
 None
 0.71A 1ikeA-1hn0A:
0.8		 1ikeA-1hn0A:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKV_A_EFZA2000_1
(POL POLYPROTEIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 9 VAL A 553
VAL A 673
GLY A 554
TRP A 546
LEU A 568
 None
 1.38A 1ikvA-1hn0A:
0.0		 1ikvA-1hn0A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 7 VAL A 837
LEU A 819
LEU A 828
ALA A 890
 None
 0.85A 1j8uA-1hn0A:
undetectable		 1j8uA-1hn0A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 10 VAL A 553
VAL A 673
GLY A 554
TRP A 546
LEU A 568
 None
 1.49A 1lw0A-1hn0A:
undetectable		 1lw0A-1hn0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 11 VAL A 553
VAL A 673
GLY A 554
TRP A 546
LEU A 568
 None
 1.47A 1lwcA-1hn0A:
0.0		 1lwcA-1hn0A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 8 GLY A 377
TRP A 397
TYR A 339
HIS A 307
 None
 1.01A 1maaD-1hn0A:
undetectable		 1maaD-1hn0A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 12 GLY A 156
VAL A 145
VAL A 157
ASN A 117
ARG A 212
 None
 1.26A 1n2xA-1hn0A:
undetectable		 1n2xA-1hn0A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 ASP A 914
LEU A 765
LEU A 759
 None
 0.71A 1np1B-1hn0A:
0.0		 1np1B-1hn0A:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 12 PHE A 113
ILE A 121
ILE A 195
ILE A 127
VAL A 145
 None
 0.98A 1r5lA-1hn0A:
undetectable		 1r5lA-1hn0A:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 11 VAL A 530
ILE A 477
LEU A 481
LEU A 578
LEU A 538
 None
 1.21A 2a15A-1hn0A:
0.0		 2a15A-1hn0A:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 11 LEU A 519
ILE A 520
GLY A 531
LEU A 481
SER A 450
 None
 1.40A 2bxeA-1hn0A:
2.7		 2bxeA-1hn0A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 7 SER A 394
SER A 450
ARG A 451
GLU A 274
 None
 1.07A 2cdqB-1hn0A:
undetectable		 2cdqB-1hn0A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 6 TYR A 873
SER A 859
GLN A 787
ASP A 863
 None
 1.26A 2cl5B-1hn0A:
0.0		 2cl5B-1hn0A:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EFJ_A_37TA502_1
(3,7-DIMETHYLXANTHINE
METHYLTRANSFERASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 12 LEU A  91
PHE A 215
ILE A 213
ILE A 210
ILE A 127
 None
 1.19A 2efjA-1hn0A:
undetectable		 2efjA-1hn0A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 7 LEU A 819
LEU A 797
GLU A 782
ARG A 692
 None
 0.79A 2jn3A-1hn0A:
2.6		 2jn3A-1hn0A:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 PHE A  44
PHE A  53
PHE A  85
 None
 0.85A 2od9A-1hn0A:
undetectable		 2od9A-1hn0A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 PHE A  44
PHE A  53
PHE A  85
 None
 0.85A 2qqgA-1hn0A:
undetectable		 2qqgA-1hn0A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 8 LYS A 539
SER A 592
ASP A 587
ALA A 616
 None
 1.42A 2rk8A-1hn0A:
2.2		 2rk8A-1hn0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 12 THR A 297
THR A 303
GLY A 302
GLY A 301
LEU A 413
 None
 1.16A 2uvnA-1hn0A:
0.0		 2uvnA-1hn0A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 VAL A 843
TRP A 688
TRP A 690
 None
 1.19A 2xdcA-1hn0A:
undetectable
2xdcB-1hn0A:
undetectable		 2xdcA-1hn0A:
1.98
2xdcB-1hn0A:
1.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 VAL A 843
TRP A 690
TRP A 688
 None
 1.48A 2xdcA-1hn0A:
undetectable
2xdcB-1hn0A:
undetectable		 2xdcA-1hn0A:
1.98
2xdcB-1hn0A:
1.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 TRP A 690
VAL A 843
TRP A 688
 None
 1.22A 2xdcA-1hn0A:
undetectable
2xdcB-1hn0A:
undetectable		 2xdcA-1hn0A:
1.98
2xdcB-1hn0A:
1.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 VAL A 843
TRP A 688
TRP A 690
 None
 1.26A 2xdcC-1hn0A:
undetectable
2xdcD-1hn0A:
undetectable		 2xdcC-1hn0A:
1.98
2xdcD-1hn0A:
1.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 TRP A 690
VAL A 843
TRP A 688
 None
 1.01A 2xdcC-1hn0A:
undetectable
2xdcD-1hn0A:
undetectable		 2xdcC-1hn0A:
1.98
2xdcD-1hn0A:
1.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 TRP A 690
VAL A 843
TRP A 688
 None
 1.02A 2xdcE-1hn0A:
undetectable
2xdcF-1hn0A:
undetectable		 2xdcE-1hn0A:
1.98
2xdcF-1hn0A:
1.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 VAL A 843
TRP A 688
TRP A 690
 None
 1.20A 2y5mA-1hn0A:
undetectable
2y5mB-1hn0A:
undetectable		 2y5mA-1hn0A:
1.98
2y5mB-1hn0A:
1.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 TRP A 690
VAL A 843
TRP A 688
 None
 1.02A 2y5mE-1hn0A:
undetectable
2y5mF-1hn0A:
undetectable		 2y5mE-1hn0A:
1.98
2y5mF-1hn0A:
1.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 VAL A 843
TRP A 688
TRP A 690
 None
 1.19A 2y6nA-1hn0A:
undetectable
2y6nB-1hn0A:
undetectable		 2y6nA-1hn0A:
1.98
2y6nB-1hn0A:
1.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 TRP A 690
VAL A 843
TRP A 688
 None
 1.19A 2y6nA-1hn0A:
undetectable
2y6nB-1hn0A:
undetectable		 2y6nA-1hn0A:
1.98
2y6nB-1hn0A:
1.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 TRP A 690
VAL A 843
TRP A 688
 None
 1.00A 2y6nC-1hn0A:
undetectable
2y6nD-1hn0A:
undetectable		 2y6nC-1hn0A:
1.98
2y6nD-1hn0A:
1.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 TRP A 690
VAL A 843
TRP A 688
 None
 1.01A 2y6nE-1hn0A:
undetectable
2y6nF-1hn0A:
undetectable		 2y6nE-1hn0A:
1.98
2y6nF-1hn0A:
1.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_B_ACTB501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 6 ASP A 258
VAL A 470
ARG A 466
ILE A 467
 None
 1.11A 2yfbB-1hn0A:
undetectable		 2yfbB-1hn0A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 6 TYR A 873
SER A 859
GLN A 787
ASP A 863
 None
 1.24A 2zvjA-1hn0A:
0.0		 2zvjA-1hn0A:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 7 SER A 201
SER A  83
LYS A 198
ASP A  56
 None
 1.23A 3bc9A-1hn0A:
undetectable		 3bc9A-1hn0A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 9 ALA A 736
GLY A 631
PRO A1012
VAL A 958
ILE A 943
 None
 1.03A 3ekvB-1hn0A:
undetectable		 3ekvB-1hn0A:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 7 THR A 920
VAL A 944
THR A 946
VAL A 955
 None
 0.41A 3em0B-1hn0A:
3.3		 3em0B-1hn0A:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 9 ALA A 736
GLY A 631
PRO A1012
VAL A 958
ILE A 943
 None
 1.17A 3em4B-1hn0A:
undetectable		 3em4B-1hn0A:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 7 GLU A 272
TYR A 594
TYR A 576
TYR A 521
 None
 1.14A 3ku9B-1hn0A:
undetectable		 3ku9B-1hn0A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 7 TYR A 594
TYR A 576
GLU A 272
TYR A 521
 None
 1.34A 3ku9B-1hn0A:
undetectable		 3ku9B-1hn0A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 ARG A 261
ASP A 462
GLN A 246
 None
 0.85A 3lcvB-1hn0A:
undetectable		 3lcvB-1hn0A:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 8 SER A 112
ARG A 212
GLN A 318
ASP A 218
 None
 1.13A 3n62A-1hn0A:
0.0		 3n62A-1hn0A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 8 SER A 112
ARG A 212
GLN A 318
ASP A 218
 None
 1.12A 3n66B-1hn0A:
0.0		 3n66B-1hn0A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 9 ALA A 736
GLY A 631
PRO A1012
VAL A 958
ILE A 943
 None
 1.09A 3nu4A-1hn0A:
undetectable		 3nu4A-1hn0A:
6.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 TYR A 664
TYR A 741
GLU A 782
 None
 0.88A 3pfgA-1hn0A:
undetectable		 3pfgA-1hn0A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 6 SER A 394
TYR A 398
ASP A 419
THR A 370
 None
 1.06A 3q70A-1hn0A:
undetectable		 3q70A-1hn0A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R6W_A_NFZA213_1
(FMN-DEPENDENT
NADH-AZOREDUCTASE 1)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 10 PHE A 129
GLY A 156
PHE A 143
VAL A  93
PHE A  31
 None
 1.31A 3r6wA-1hn0A:
0.0
3r6wB-1hn0A:
undetectable		 3r6wA-1hn0A:
13.07
3r6wB-1hn0A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 8 VAL A 417
LEU A 421
LEU A 402
THR A 401
 None
 0.76A 3roxA-1hn0A:
undetectable		 3roxA-1hn0A:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 6 MET A 735
LEU A 642
GLN A 671
PRO A 556
 None
 1.33A 3vkxA-1hn0A:
0.1		 3vkxA-1hn0A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 VAL A 843
TRP A 688
TRP A 690
 None
 1.15A 3zq8A-1hn0A:
undetectable
3zq8B-1hn0A:
undetectable		 3zq8A-1hn0A:
1.98
3zq8B-1hn0A:
1.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1480_0
(MJ0495-LIKE PROTEIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 4 LYS A 755
GLU A 874
ILE A 768
SER A 757
 None
 0.95A 4ac9C-1hn0A:
undetectable		 4ac9C-1hn0A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1480_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 4 LYS A 755
GLU A 874
ILE A 768
SER A 757
 None
 0.93A 4acaC-1hn0A:
0.0		 4acaC-1hn0A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1480_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 4 LYS A 755
GLU A 874
ILE A 768
SER A 757
 None
 0.96A 4acbC-1hn0A:
0.0		 4acbC-1hn0A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 TRP A 390
TRP A 397
THR A 340
 None
 1.13A 4bboB-1hn0A:
1.4		 4bboB-1hn0A:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 TRP A 983
TRP A 934
THR A 946
 None
 1.44A 4bboB-1hn0A:
1.4		 4bboB-1hn0A:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 10 ALA A 736
GLY A 631
PRO A1012
VAL A 958
ILE A 943
 None
 1.03A 4dqcA-1hn0A:
undetectable		 4dqcA-1hn0A:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 11 ALA A 736
GLY A 631
PRO A1012
VAL A 958
ILE A 943
 None
 0.97A 4dqhA-1hn0A:
undetectable		 4dqhA-1hn0A:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 4 SER A 440
LEU A 519
TYR A 476
PRO A 485
 None
 1.48A 4jksA-1hn0A:
0.0		 4jksA-1hn0A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 4 SER A 440
LEU A 519
TYR A 476
PRO A 485
 None
 1.48A 4jksB-1hn0A:
0.0		 4jksB-1hn0A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 4 SER A 440
LEU A 519
TYR A 476
PRO A 485
 None
 1.48A 4jkuA-1hn0A:
0.0		 4jkuA-1hn0A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_2
(SUGAR KINASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 4 SER A 440
LEU A 519
TYR A 476
PRO A 485
 None
 1.46A 4k8kA-1hn0A:
0.0		 4k8kA-1hn0A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_2
(SUGAR KINASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 4 SER A 440
LEU A 519
TYR A 476
PRO A 485
 None
 1.47A 4k8kB-1hn0A:
0.0		 4k8kB-1hn0A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 4 SER A 440
LEU A 519
TYR A 476
PRO A 485
 None
 1.47A 4kalB-1hn0A:
undetectable		 4kalB-1hn0A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 4 SER A 440
LEU A 519
TYR A 476
PRO A 485
 None
 1.46A 4lcaB-1hn0A:
0.0		 4lcaB-1hn0A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 8 ALA A 736
GLY A 631
PRO A1012
VAL A 958
ILE A 943
 None
 1.24A 4ll3A-1hn0A:
undetectable		 4ll3A-1hn0A:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 5 TYR A 124
LEU A 115
ASP A 226
VAL A 110
 None
 1.21A 4nkvA-1hn0A:
0.0		 4nkvA-1hn0A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 10 ALA A 736
GLY A 631
PRO A1012
VAL A 958
ILE A 943
 None
 1.02A 4q1wB-1hn0A:
undetectable		 4q1wB-1hn0A:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 6 LEU A 797
GLU A 805
ASN A 795
ILE A 790
 None
 0.91A 4ww7A-1hn0A:
2.4		 4ww7A-1hn0A:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_A_GBMA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 11 TYR A 741
HIS A 667
ILE A 654
LEU A 701
LEU A 706
 None
 1.10A 4yvpA-1hn0A:
undetectable		 4yvpA-1hn0A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 12 ASN A 504
PHE A 630
LEU A 557
SER A 544
SER A 509
 None
 1.49A 4zbrA-1hn0A:
2.4		 4zbrA-1hn0A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 4 VAL A 944
ILE A 979
ASN A 976
VAL A 992
 None
 1.20A 5ajqA-1hn0A:
0.3		 5ajqA-1hn0A:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 7 ALA A 644
GLY A 769
THR A 830
GLU A 874
 None
 0.90A 5btgA-1hn0A:
0.5
5btgC-1hn0A:
0.5
5btgD-1hn0A:
undetectable		 5btgA-1hn0A:
19.25
5btgC-1hn0A:
19.25
5btgD-1hn0A:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 8 GLN A 684
ILE A 790
GLY A 682
LEU A 679
 None
 0.97A 5hwaA-1hn0A:
0.0		 5hwaA-1hn0A:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 12 ILE A 213
LEU A 115
LEU A 125
VAL A 145
PHE A 111
 None
 1.19A 5im2A-1hn0A:
0.0		 5im2A-1hn0A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 4 ASN A 515
LEU A 519
SER A 517
LEU A 481
 None
 1.33A 5kb5A-1hn0A:
undetectable		 5kb5A-1hn0A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 ARG A 348
ILE A 399
PHE A 268
 None
 0.69A 5kirA-1hn0A:
1.4		 5kirA-1hn0A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_1
(PROTEASE E35D-APV)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 9 ALA A 736
GLY A 631
PRO A1012
VAL A 958
ILE A 943
 None
 1.15A 5kr0A-1hn0A:
undetectable		 5kr0A-1hn0A:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODH_G_ACTG710_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 4 ARG A 904
ILE A 911
TYR A 922
ILE A 935
 None
 1.45A 5odhG-1hn0A:
0.0		 5odhG-1hn0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 LYS A 312
HIS A 389
HIS A 388
 None
 1.39A 5oexA-1hn0A:
2.3		 5oexA-1hn0A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		3 / 3 LYS A 312
HIS A 389
HIS A 388
 None
 1.38A 5oexD-1hn0A:
2.1		 5oexD-1hn0A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 4 LEU A 522
LEU A 264
SER A 450
ALA A 455
 None
 1.07A 5uunA-1hn0A:
3.0		 5uunA-1hn0A:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 8 SER A 112
ARG A 212
GLN A 318
ASP A 218
 None
 1.23A 5vunA-1hn0A:
0.0		 5vunA-1hn0A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 8 SER A 112
ARG A 212
GLN A 318
ASP A 218
 None
 1.14A 5vunB-1hn0A:
0.0		 5vunB-1hn0A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 8 SER A 112
ARG A 212
GLN A 318
ASP A 218
 None
 1.15A 5vuoB-1hn0A:
0.0		 5vuoB-1hn0A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA609_0
(ALPHA-AMYLASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 7 GLY A 507
ASP A 490
TRP A 499
TYR A 508
 None
 0.94A 6ag0A-1hn0A:
3.4		 6ag0A-1hn0A:
6.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 8 SER A 112
ARG A 212
GLN A 318
ASP A 218
 None
 1.16A 6auuB-1hn0A:
0.0		 6auuB-1hn0A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 7 PHE A 446
ALA A 480
GLN A 483
GLN A 452
 None
 1.13A 6b89A-1hn0A:
0.0		 6b89A-1hn0A:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 10 ALA A 736
GLY A 631
PRO A1012
VAL A 958
ILE A 943
 None
 1.02A 6dj2A-1hn0A:
undetectable		 6dj2A-1hn0A:
6.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 10 SER A 474
LEU A 578
SER A 581
ASP A 525
GLY A 534
 None
 1.45A 6dlzA-1hn0A:
2.1
6dlzD-1hn0A:
2.8		 6dlzA-1hn0A:
6.61
6dlzD-1hn0A:
6.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 10 GLY A 534
SER A 474
LEU A 578
SER A 581
ASP A 525
 None
 1.46A 6dlzB-1hn0A:
2.7
6dlzC-1hn0A:
2.1		 6dlzB-1hn0A:
6.61
6dlzC-1hn0A:
6.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 10 SER A 474
LEU A 578
SER A 581
ASP A 525
GLY A 534
 None
 1.46A 6dm1A-1hn0A:
2.1
6dm1D-1hn0A:
2.8		 6dm1A-1hn0A:
6.61
6dm1D-1hn0A:
6.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		5 / 10 GLY A 534
SER A 474
LEU A 578
SER A 581
ASP A 525
 None
 1.46A 6dm1B-1hn0A:
2.8
6dm1C-1hn0A:
2.1		 6dm1B-1hn0A:
6.61
6dm1C-1hn0A:
6.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 1hn0 CHONDROITIN ABC
LYASE I
(Proteus
vulgaris) 		4 / 7 GLY A 123
ASN A 117
GLU A 207
GLY A 206
 None
 0.85A 6n7fA-1hn0A:
undetectable		 6n7fA-1hn0A:
7.46