SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hna'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1hna GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		4 / 6 ARG A  17
ALA A  13
ILE A  75
PRO A  60
 None
None
None
GDN  A 218 ( 4.6A)
 1.27A 1oniB-1hnaA:
undetectable
1oniC-1hnaA:
undetectable		 1oniB-1hnaA:
23.33
1oniC-1hnaA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1hna GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		4 / 7 ILE A  69
MET A   2
LEU A  20
LEU A  76
 None
 1.00A 2qqcB-1hnaA:
undetectable
2qqcC-1hnaA:
undetectable		 2qqcB-1hnaA:
20.28
2qqcC-1hnaA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1hna GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		4 / 7 LEU A  20
LEU A  76
ILE A  69
MET A   2
 None
 0.98A 2qqcG-1hnaA:
undetectable
2qqcJ-1hnaA:
undetectable		 2qqcG-1hnaA:
17.53
2qqcJ-1hnaA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1hna GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		4 / 7 LEU A  20
LEU A  76
ILE A  69
MET A   2
 None
 0.99A 2qqcI-1hnaA:
undetectable
2qqcL-1hnaA:
0.0		 2qqcI-1hnaA:
17.53
2qqcL-1hnaA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 1hna GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		4 / 6 LEU A 141
SER A 138
TYR A 137
LEU A 134
 None
 0.93A 3f33A-1hnaA:
undetectable		 3f33A-1hnaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 1hna GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		4 / 4 ILE A  98
ASN A 101
ILE A 158
VAL A 155
 None
 1.13A 4uy87-1hnaA:
undetectable		 4uy87-1hnaA:
6.70