SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hng'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 1hng CD2
(Rattus
rattus) 		4 / 7 ARG A  34
ASP A  71
THR A  69
ILE A  65
 None
 1.23A 2jc9A-1hngA:
undetectable		 2jc9A-1hngA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 1hng CD2
(Rattus
rattus) 		3 / 3 GLU A 168
SER A 102
VAL A 101
 None
 0.78A 3eeoA-1hngA:
undetectable		 3eeoA-1hngA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 1hng CD2
(Rattus
rattus) 		3 / 3 ASN A  60
LEU A  89
PHE A  42
 None
 0.79A 4dajB-1hngA:
undetectable		 4dajB-1hngA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1hng CD2
(Rattus
rattus) 		3 / 3 VAL A  39
THR A  37
ARG A  34
 None
 0.66A 5b2sB-1hngA:
undetectable		 5b2sB-1hngA:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1hng CD2
(Rattus
rattus) 		3 / 3 VAL A  39
THR A  37
ARG A  34
 None
 0.61A 5b2tB-1hngA:
undetectable		 5b2tB-1hngA:
8.65