SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hom'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		5 / 12 GLU A  15
LEU A  26
ILE A  45
LEU A  40
HIS A  36
 None
 1.24A 1kyvA-1homA:
undetectable
1kyvE-1homA:
undetectable		 1kyvA-1homA:
15.29
1kyvE-1homA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		5 / 12 LEU A  40
HIS A  36
GLU A  15
LEU A  26
ILE A  45
 None
 1.24A 1kyvB-1homA:
undetectable
1kyvC-1homA:
undetectable		 1kyvB-1homA:
15.29
1kyvC-1homA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		5 / 12 LEU A  40
HIS A  36
GLU A  15
LEU A  26
ILE A  45
 None
 1.23A 1kyvC-1homA:
undetectable
1kyvD-1homA:
undetectable		 1kyvC-1homA:
15.29
1kyvD-1homA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		5 / 12 LEU A  40
HIS A  36
GLU A  15
LEU A  26
ILE A  45
 None
 1.22A 1kyvD-1homA:
undetectable
1kyvE-1homA:
undetectable		 1kyvD-1homA:
15.29
1kyvE-1homA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		4 / 6 LEU A  38
ARG A  29
THR A  27
LEU A  26
 None
 0.95A 1v54A-1homA:
undetectable
1v54J-1homA:
0.0		 1v54A-1homA:
8.24
1v54J-1homA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		4 / 7 LEU A  38
ARG A  29
THR A  27
LEU A  26
 None
 0.94A 1v55A-1homA:
undetectable
1v55J-1homA:
0.0		 1v55A-1homA:
8.24
1v55J-1homA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		4 / 6 LEU A  38
ARG A  29
THR A  27
LEU A  26
 None
 0.98A 2dyrA-1homA:
undetectable
2dyrJ-1homA:
0.0		 2dyrA-1homA:
8.24
2dyrJ-1homA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		4 / 6 LEU A  38
ARG A  29
THR A  27
LEU A  26
 None
 1.02A 2dysA-1homA:
undetectable
2dysJ-1homA:
0.0		 2dysA-1homA:
8.24
2dysJ-1homA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		4 / 6 LEU A  38
ARG A  29
THR A  27
LEU A  26
 None
 0.99A 2dysN-1homA:
undetectable
2dysW-1homA:
0.0		 2dysN-1homA:
8.24
2dysW-1homA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		4 / 6 LEU A  38
ARG A  29
THR A  27
LEU A  26
 None
 0.95A 2eijA-1homA:
undetectable
2eijJ-1homA:
0.0		 2eijA-1homA:
8.24
2eijJ-1homA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		4 / 6 LEU A  38
ARG A  29
THR A  27
LEU A  26
 None
 0.93A 2eilA-1homA:
undetectable
2eilJ-1homA:
0.0		 2eilA-1homA:
8.24
2eilJ-1homA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		4 / 6 LEU A  38
ARG A  29
THR A  27
LEU A  26
 None
 1.01A 3abmA-1homA:
undetectable
3abmJ-1homA:
0.0		 3abmA-1homA:
8.24
3abmJ-1homA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		4 / 6 LEU A  38
ARG A  29
THR A  27
LEU A  26
 None
 1.00A 3asnA-1homA:
undetectable
3asnJ-1homA:
0.0		 3asnA-1homA:
8.24
3asnJ-1homA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		4 / 6 LEU A  38
ARG A  29
THR A  27
LEU A  26
 None
 0.99A 3asoA-1homA:
undetectable
3asoJ-1homA:
0.1		 3asoA-1homA:
8.24
3asoJ-1homA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		3 / 3 TRP A  48
ARG A  52
LEU A  26
 None
 0.92A 5dbyA-1homA:
undetectable		 5dbyA-1homA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		4 / 6 LEU A  38
ARG A  29
THR A  27
LEU A  26
 None
 1.09A 5x1fA-1homA:
undetectable
5x1fJ-1homA:
0.1		 5x1fA-1homA:
8.24
5x1fJ-1homA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1hom ANTENNAPEDIA PROTEIN
(Drosophila
melanogaster) 		4 / 7 LEU A  38
ARG A  29
THR A  27
LEU A  26
 None
 0.99A 6nmfA-1homA:
undetectable
6nmfJ-1homA:
0.1		 6nmfA-1homA:
8.24
6nmfJ-1homA:
16.42