SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hq8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1hq8 NKG2-D
(Mus
musculus) 		3 / 3 LYS A 152
SER A 191
GLN A 194
 None
 0.83A 3si7A-1hq8A:
undetectable		 3si7A-1hq8A:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1hq8 NKG2-D
(Mus
musculus) 		3 / 3 SER A 204
ALA A 206
VAL A 207
 None
 0.68A 4o2bC-1hq8A:
undetectable		 4o2bC-1hq8A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 1hq8 NKG2-D
(Mus
musculus) 		4 / 5 LEU A 195
LEU A 197
GLN A 159
TYR A 154
 None
 1.37A 5uc3A-1hq8A:
0.0		 5uc3A-1hq8A:
21.51