SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hqz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1hqz ACTIN-BINDING
PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 GLY 1  67
SER 1  36
SER 1  47
GLU 1  46
 None
 0.95A 2c8aB-1hqz1:
undetectable		 2c8aB-1hqz1:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1hqz ACTIN-BINDING
PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 GLY 1  67
SER 1  36
SER 1  47
GLU 1  46
 None
 0.97A 2c8aD-1hqz1:
undetectable		 2c8aD-1hqz1:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1hqz ACTIN-BINDING
PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 ILE 1  35
ILE 1   6
LEU 1 126
 None
 0.57A 2prgA-1hqz1:
undetectable		 2prgA-1hqz1:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1hqz ACTIN-BINDING
PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 PHE 1  99
ASP 1   7
ILE 1   6
ALA 1 105
VAL 1 106
 None
 1.18A 4dx5B-1hqz1:
undetectable		 4dx5B-1hqz1:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 1hqz ACTIN-BINDING
PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 VAL 1  23
TYR 1  19
ILE 1 135
VAL 1 116
ILE 1  84
 None
 1.43A 4eb6B-1hqz1:
undetectable
4eb6C-1hqz1:
undetectable		 4eb6B-1hqz1:
16.85
4eb6C-1hqz1:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1hqz ACTIN-BINDING
PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 PHE 1  99
ASP 1   7
ILE 1   6
ALA 1 105
VAL 1 106
 None
 1.16A 4u8vB-1hqz1:
undetectable		 4u8vB-1hqz1:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1hqz ACTIN-BINDING
PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 PHE 1  99
ASP 1   7
ILE 1   6
ALA 1 105
VAL 1 106
 None
 1.17A 4u95B-1hqz1:
undetectable		 4u95B-1hqz1:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 1hqz ACTIN-BINDING
PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 ILE 1  81
THR 1  31
ILE 1  22
PHE 1  55
PHE 1  52
 None
 1.19A 6hlpA-1hqz1:
undetectable		 6hlpA-1hqz1:
13.51