SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1htd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		5 / 10 ALA A 111
LEU A  10
VAL A  37
TYR A  44
ILE A   8
 None
 1.23A 1claA-1htdA:
0.0		 1claA-1htdA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 7 VAL A 126
ILE A 125
HIS A  92
LEU A  86
 None
 0.94A 1j96B-1htdA:
0.0		 1j96B-1htdA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.23A 1os2A-1htdA:
11.0		 1os2A-1htdA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.19A 1os2D-1htdA:
11.0		 1os2D-1htdA:
22.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R55_A_097A518_1
(ADAM 33)		 1htd ATROLYSIN C
(Crotalus
atrox) 		6 / 10 THR A 107
THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.33A 1r55A-1htdA:
30.1		 1r55A-1htdA:
34.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.21A 1uttA-1htdA:
11.4		 1uttA-1htdA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.21A 1utzA-1htdA:
11.3		 1utzA-1htdA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.19A 1utzB-1htdA:
11.3		 1utzB-1htdA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 1htd ATROLYSIN C
(Crotalus
atrox) 		3 / 3 ARG A  32
TYR A  22
LYS A  21
 None
 1.07A 1uujB-1htdA:
0.0		 1uujB-1htdA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.22A 1y93A-1htdA:
11.4		 1y93A-1htdA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 8 ASP A 153
SER A 182
TYR A 185
HIS A 146
 None
None
None
ZN  A 401 ( 3.2A)
 1.25A 2bteA-1htdA:
0.4		 2bteA-1htdA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.16A 2hu6A-1htdA:
11.4		 2hu6A-1htdA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 1htd ATROLYSIN C
(Crotalus
atrox) 		6 / 9 LEU A 108
THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.46A 2jihA-1htdA:
25.4		 2jihA-1htdA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 1htd ATROLYSIN C
(Crotalus
atrox) 		5 / 9 LEU A 170
THR A 139
HIS A 142
HIS A 146
HIS A 152
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 1.39A 2jihA-1htdA:
25.4		 2jihA-1htdA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 1htd ATROLYSIN C
(Crotalus
atrox) 		6 / 8 LEU A 108
HIS A 142
GLU A 143
HIS A 146
HIS A 152
LEU A 170
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
None
 0.58A 2jihB-1htdA:
25.3		 2jihB-1htdA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 1htd ATROLYSIN C
(Crotalus
atrox) 		6 / 8 LEU A 108
THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.45A 2jihB-1htdA:
25.3		 2jihB-1htdA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 1htd ATROLYSIN C
(Crotalus
atrox) 		5 / 8 LEU A 170
THR A 139
HIS A 142
HIS A 146
HIS A 152
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 1.29A 2jihB-1htdA:
25.3		 2jihB-1htdA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.25A 2ow9A-1htdA:
10.9		 2ow9A-1htdA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.24A 2ow9B-1htdA:
10.7		 2ow9B-1htdA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.25A 2ozrC-1htdA:
10.6		 2ozrC-1htdA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.24A 2ozrD-1htdA:
10.7		 2ozrD-1htdA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.25A 2ozrE-1htdA:
10.7		 2ozrE-1htdA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 1htd ATROLYSIN C
(Crotalus
atrox) 		3 / 3 HIS A 142
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.23A 2ozrF-1htdA:
10.6		 2ozrF-1htdA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 8 ASP A 153
SER A 182
TYR A 185
HIS A 146
 None
None
None
ZN  A 401 ( 3.2A)
 1.15A 2v0gA-1htdA:
undetectable		 2v0gA-1htdA:
12.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W13_A_ACTA1208_0
(ZINC
METALLOPROTEINASE
BAP1)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 4 THR A  31
ARG A  32
GLU A  35
ASN A 133
 None
 1.12A 2w13A-1htdA:
34.8		 2w13A-1htdA:
59.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1htd ATROLYSIN C
(Crotalus
atrox) 		6 / 9 LEU A 108
HIS A 142
GLU A 143
HIS A 146
HIS A 152
LEU A 170
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
None
 0.85A 3hy7A-1htdA:
26.0		 3hy7A-1htdA:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1htd ATROLYSIN C
(Crotalus
atrox) 		6 / 9 LEU A 108
THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.42A 3hy7A-1htdA:
26.0		 3hy7A-1htdA:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1htd ATROLYSIN C
(Crotalus
atrox) 		7 / 9 LEU A 108
THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
LEU A 170
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
None
 0.68A 3hy7B-1htdA:
25.7		 3hy7B-1htdA:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.21A 3kecA-1htdA:
10.9		 3kecA-1htdA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.21A 3likA-1htdA:
11.4		 3likA-1htdA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.21A 3lilA-1htdA:
11.5		 3lilA-1htdA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.21A 3ljgA-1htdA:
11.5		 3ljgA-1htdA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.18A 3lkaA-1htdA:
11.4		 3lkaA-1htdA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1htd ATROLYSIN C
(Crotalus
atrox) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 198
 None
 1.11A 3ut5B-1htdA:
undetectable		 3ut5B-1htdA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.33A 4a7bA-1htdA:
10.7		 4a7bA-1htdA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 1htd ATROLYSIN C
(Crotalus
atrox) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 198
 None
 1.07A 4o2bB-1htdA:
undetectable		 4o2bB-1htdA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 6 ASN A  41
MET A 166
MET A 150
LEU A  47
 None
 1.09A 4okxA-1htdA:
0.0		 4okxA-1htdA:
26.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 1htd ATROLYSIN C
(Crotalus
atrox) 		3 / 3 LEU A  98
LEU A  86
ASN A  94
 None
 0.73A 4otwA-1htdA:
undetectable		 4otwA-1htdA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 1htd ATROLYSIN C
(Crotalus
atrox) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 198
 None
 1.02A 4x1iD-1htdA:
undetectable		 4x1iD-1htdA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1htd ATROLYSIN C
(Crotalus
atrox) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 198
 None
 1.00A 4x1yB-1htdA:
undetectable		 4x1yB-1htdA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 1htd ATROLYSIN C
(Crotalus
atrox) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 198
 None
 0.99A 4x1yD-1htdA:
undetectable		 4x1yD-1htdA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 1htd ATROLYSIN C
(Crotalus
atrox) 		5 / 11 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 198
 None
 1.02A 4x20D-1htdA:
undetectable		 4x20D-1htdA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 4 LEU A 170
ILE A 165
HIS A 142
VAL A 138
 None
None
ZN  A 401 ( 3.2A)
None
 1.20A 4xyzA-1htdA:
undetectable		 4xyzA-1htdA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 1htd ATROLYSIN C
(Crotalus
atrox) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 198
 None
 1.01A 5itzB-1htdA:
1.0		 5itzB-1htdA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1htd ATROLYSIN C
(Crotalus
atrox) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 198
 None
 1.08A 5mioB-1htdA:
undetectable		 5mioB-1htdA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.18A 5n5jA-1htdA:
11.5		 5n5jA-1htdA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.2A)
 0.18A 5n5kA-1htdA:
11.5		 5n5kA-1htdA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		3 / 3 HIS A  92
SER A  91
ARG A  89
 None
 0.98A 5u63A-1htdA:
undetectable		 5u63A-1htdA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 1htd ATROLYSIN C
(Crotalus
atrox) 		5 / 9 VAL A  33
ILE A 125
LEU A  97
ARG A  32
ASP A 128
 None
 1.45A 6c2mC-1htdA:
0.0		 6c2mC-1htdA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 1htd ATROLYSIN C
(Crotalus
atrox) 		4 / 4 HIS A  92
VAL A  13
LEU A  86
ALA A  95
 None
 1.41A 6d8pB-1htdA:
0.0		 6d8pB-1htdA:
12.66