SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1htj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1866_0
(FPRA)		 1htj KIAA0380
(Homo
sapiens) 		4 / 4 ARG F 329
LEU F 436
ASN F 434
VAL F 326
 None
 1.43A 1lqtA-1htjF:
undetectable		 1lqtA-1htjF:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 1htj KIAA0380
(Homo
sapiens) 		3 / 3 ALA F 322
HIS F 323
VAL F 326
 None
 0.28A 1lqtB-1htjF:
undetectable		 1lqtB-1htjF:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1875_0
(FPRA)		 1htj KIAA0380
(Homo
sapiens) 		4 / 4 ARG F 329
LEU F 436
ASN F 434
VAL F 326
 None
 1.43A 1lqtB-1htjF:
undetectable		 1lqtB-1htjF:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1423_0
(FPRA)		 1htj KIAA0380
(Homo
sapiens) 		4 / 4 ARG F 329
LEU F 436
ASN F 434
VAL F 326
 None
 1.42A 1lquA-1htjF:
undetectable		 1lquA-1htjF:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 1htj KIAA0380
(Homo
sapiens) 		3 / 3 ALA F 322
HIS F 323
VAL F 326
 None
 0.26A 1lquB-1htjF:
undetectable		 1lquB-1htjF:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1432_0
(FPRA)		 1htj KIAA0380
(Homo
sapiens) 		4 / 4 ARG F 329
LEU F 436
ASN F 434
VAL F 326
 None
 1.43A 1lquB-1htjF:
undetectable		 1lquB-1htjF:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1htj KIAA0380
(Homo
sapiens) 		5 / 8 PHE F 332
SER F 333
ARG F 329
ALA F 456
LEU F 457
 None
 1.35A 2o01A-1htjF:
0.9		 2o01A-1htjF:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 1htj KIAA0380
(Homo
sapiens) 		5 / 11 LEU F 324
LEU F 317
ARG F 320
PHE F 311
LEU F 436
 None
 1.02A 2q6hA-1htjF:
0.0		 2q6hA-1htjF:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 1htj KIAA0380
(Homo
sapiens) 		5 / 12 LEU F 324
LEU F 317
ARG F 320
PHE F 311
LEU F 436
 None
 1.00A 2qb4A-1htjF:
0.0		 2qb4A-1htjF:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 1htj KIAA0380
(Homo
sapiens) 		5 / 11 LEU F 324
LEU F 317
ARG F 320
PHE F 311
LEU F 436
 None
 1.00A 2qeiA-1htjF:
0.0		 2qeiA-1htjF:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 1htj KIAA0380
(Homo
sapiens) 		5 / 11 LEU F 324
LEU F 317
ARG F 320
PHE F 311
LEU F 436
 None
 0.98A 2qjuA-1htjF:
undetectable		 2qjuA-1htjF:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1htj KIAA0380
(Homo
sapiens) 		5 / 9 LEU F 383
LEU F 369
ALA F 397
ALA F 346
PHE F 342
 None
 0.99A 2vcvD-1htjF:
undetectable		 2vcvD-1htjF:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1htj KIAA0380
(Homo
sapiens) 		5 / 9 LEU F 383
LEU F 369
ALA F 397
ALA F 346
PHE F 342
 None
 0.94A 2vcvE-1htjF:
0.1		 2vcvE-1htjF:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1htj KIAA0380
(Homo
sapiens) 		5 / 9 LEU F 383
LEU F 369
ALA F 397
ALA F 346
PHE F 342
 None
 0.98A 2vcvH-1htjF:
0.2		 2vcvH-1htjF:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1htj KIAA0380
(Homo
sapiens) 		5 / 9 LEU F 383
LEU F 369
ALA F 397
ALA F 346
PHE F 342
 None
 0.92A 2vcvI-1htjF:
undetectable		 2vcvI-1htjF:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 1htj KIAA0380
(Homo
sapiens) 		5 / 12 GLY F 361
ALA F 346
ALA F 404
LEU F 369
VAL F 377
 None
 0.78A 2yqzB-1htjF:
undetectable		 2yqzB-1htjF:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1htj KIAA0380
(Homo
sapiens) 		4 / 6 GLN F 334
TYR F 431
GLN F 453
SER F 333
 None
 1.29A 3peoG-1htjF:
undetectable		 3peoG-1htjF:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 1htj KIAA0380
(Homo
sapiens) 		4 / 7 GLU F 433
GLY F 426
TYR F 419
GLY F 428
 None
 0.85A 4rdxA-1htjF:
undetectable		 4rdxA-1htjF:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZAU_A_YY3A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 1htj KIAA0380
(Homo
sapiens) 		5 / 8 LEU F 401
GLY F 399
VAL F 400
LEU F 369
GLY F 361
 None
 1.06A 4zauA-1htjF:
undetectable		 4zauA-1htjF:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1htj KIAA0380
(Homo
sapiens) 		5 / 12 LEU F 324
LEU F 344
ALA F 475
ARG F 329
GLY F 458
 None
 1.04A 6b0iB-1htjF:
undetectable		 6b0iB-1htjF:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 1htj KIAA0380
(Homo
sapiens) 		4 / 5 LEU F 324
THR F 478
PRO F 374
ARG F 376
 None
 1.09A 6ew0F-1htjF:
undetectable		 6ew0F-1htjF:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 1htj KIAA0380
(Homo
sapiens) 		4 / 6 LEU F 324
THR F 478
PRO F 374
ARG F 376
 None
 1.08A 6ew0G-1htjF:
undetectable		 6ew0G-1htjF:
15.54