SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1htp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1htp H-PROTEIN
(Pisum
sativum) 		4 / 8 PHE A  56
VAL A  41
LEU A  43
VAL A  59
 None
 0.78A 2zujA-1htpA:
undetectable		 2zujA-1htpA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1htp H-PROTEIN
(Pisum
sativum) 		5 / 12 GLU A  14
GLY A  55
VAL A  38
SER A  12
ILE A  27
 OSS  A 132 (-3.5A)
None
None
None
OSS  A 132 ( 4.2A)
 1.24A 3k13A-1htpA:
undetectable		 3k13A-1htpA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1htp H-PROTEIN
(Pisum
sativum) 		5 / 12 GLU A  14
GLY A  55
VAL A  38
SER A  12
ILE A  27
 OSS  A 132 (-3.5A)
None
None
None
OSS  A 132 ( 4.2A)
 1.25A 3k13B-1htpA:
undetectable		 3k13B-1htpA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1htp H-PROTEIN
(Pisum
sativum) 		5 / 12 GLU A  14
GLY A  55
VAL A  38
SER A  12
ILE A  27
 OSS  A 132 (-3.5A)
None
None
None
OSS  A 132 ( 4.2A)
 1.25A 3k13C-1htpA:
undetectable		 3k13C-1htpA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 1htp H-PROTEIN
(Pisum
sativum) 		4 / 7 VAL A  16
GLY A  26
VAL A  76
VAL A  50
 None
 0.82A 3ufnB-1htpA:
0.0		 3ufnB-1htpA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 1htp H-PROTEIN
(Pisum
sativum) 		4 / 6 THR A  28
TYR A 120
HIS A  34
TYR A  95
 None
None
OSS  A 132 (-4.3A)
None
 1.45A 4df2A-1htpA:
undetectable		 4df2A-1htpA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 1htp H-PROTEIN
(Pisum
sativum) 		4 / 8 GLY A  26
PRO A  71
PHE A  56
ILE A 101
 None
 0.98A 4j4vC-1htpA:
undetectable		 4j4vC-1htpA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1htp H-PROTEIN
(Pisum
sativum) 		4 / 8 ALA A  10
GLU A  14
ILE A  25
ILE A 103
 None
OSS  A 132 (-3.5A)
None
None
 0.85A 4kttB-1htpA:
undetectable		 4kttB-1htpA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1htp H-PROTEIN
(Pisum
sativum) 		4 / 8 ALA A  10
GLU A  14
ILE A  25
ILE A 103
 None
OSS  A 132 (-3.5A)
None
None
 0.82A 4kttD-1htpA:
undetectable		 4kttD-1htpA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1htp H-PROTEIN
(Pisum
sativum) 		4 / 8 ALA A  10
GLU A  14
ILE A  25
ILE A 103
 None
OSS  A 132 (-3.5A)
None
None
 0.85A 4ndnB-1htpA:
undetectable		 4ndnB-1htpA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1htp H-PROTEIN
(Pisum
sativum) 		4 / 4 GLY A  55
ALA A  58
MET A 100
THR A  65
 None
 1.46A 5n0sB-1htpA:
undetectable		 5n0sB-1htpA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1htp H-PROTEIN
(Pisum
sativum) 		5 / 12 GLU A  14
GLY A  55
VAL A  38
SER A  12
ILE A  27
 OSS  A 132 (-3.5A)
None
None
None
OSS  A 132 ( 4.2A)
 1.17A 5vooB-1htpA:
undetectable		 5vooB-1htpA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1htp H-PROTEIN
(Pisum
sativum) 		5 / 12 GLU A  14
GLY A  55
VAL A  38
SER A  12
ILE A  27
 OSS  A 132 (-3.5A)
None
None
None
OSS  A 132 ( 4.2A)
 1.16A 5vooE-1htpA:
undetectable		 5vooE-1htpA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1htp H-PROTEIN
(Pisum
sativum) 		5 / 12 GLU A  14
GLY A  55
VAL A  38
SER A  12
ILE A  27
 OSS  A 132 (-3.5A)
None
None
None
OSS  A 132 ( 4.2A)
 1.15A 5vopB-1htpA:
undetectable		 5vopB-1htpA:
18.39