SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hu8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1hu8 CELLULAR TUMOR
ANTIGEN P53
(Mus
musculus) 		4 / 7 ILE A 252
PHE A 267
TYR A 233
THR A 137
 None
 0.98A 2zxwN-1hu8A:
undetectable
2zxwW-1hu8A:
undetectable		 2zxwN-1hu8A:
15.26
2zxwW-1hu8A:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1hu8 CELLULAR TUMOR
ANTIGEN P53
(Mus
musculus) 		4 / 7 ILE A 252
PHE A 267
TYR A 233
THR A 137
 None
 1.03A 3ag2N-1hu8A:
undetectable
3ag2W-1hu8A:
0.0		 3ag2N-1hu8A:
15.26
3ag2W-1hu8A:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1hu8 CELLULAR TUMOR
ANTIGEN P53
(Mus
musculus) 		4 / 7 ILE A 252
PHE A 267
TYR A 233
THR A 137
 None
 1.02A 3ag4N-1hu8A:
undetectable
3ag4W-1hu8A:
0.0		 3ag4N-1hu8A:
15.26
3ag4W-1hu8A:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1hu8 CELLULAR TUMOR
ANTIGEN P53
(Mus
musculus) 		4 / 8 TYR A 202
LEU A 203
ALA A 158
THR A 250
 None
 0.81A 3jusB-1hu8A:
undetectable		 3jusB-1hu8A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 1hu8 CELLULAR TUMOR
ANTIGEN P53
(Mus
musculus) 		4 / 8 TYR A 231
LEU A 142
LEU A 108
THR A  99
 None
 1.12A 5hs6A-1hu8A:
undetectable		 5hs6A-1hu8A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1hu8 CELLULAR TUMOR
ANTIGEN P53
(Mus
musculus) 		4 / 5 ILE A 252
PHE A 267
TYR A 233
THR A 137
 None
 1.01A 5z84N-1hu8A:
undetectable
5z84W-1hu8A:
0.0		 5z84N-1hu8A:
15.26
5z84W-1hu8A:
15.98