SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1huq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 1huq RAB5C
(Mus
musculus) 		3 / 3 PHE A  46
LEU A  37
SER A 164
 GNP  A 200 (-4.1A)
None
GNP  A 200 (-3.5A)
 0.78A 1e7aA-1huqA:
undetectable		 1e7aA-1huqA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 1huq RAB5C
(Mus
musculus) 		5 / 9 VAL A 100
GLY A 133
GLN A  80
ASN A 134
GLY A  33
 None
None
None
GNP  A 200 (-3.3A)
GNP  A 200 (-3.4A)
 1.42A 3kmoA-1huqA:
0.0		 3kmoA-1huqA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1huq RAB5C
(Mus
musculus) 		5 / 9 GLU A 118
ALA A 123
ILE A 129
VAL A  99
ALA A  94
 None
 1.10A 4lbgB-1huqA:
3.2		 4lbgB-1huqA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1huq RAB5C
(Mus
musculus) 		3 / 3 LYS A 181
LEU A  24
ILE A 174
 None
 0.77A 5kc0A-1huqA:
undetectable		 5kc0A-1huqA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1huq RAB5C
(Mus
musculus) 		5 / 12 VAL A  70
PHE A  22
GLN A  95
ILE A 129
ALA A 130
 None
 1.11A 5n0sB-1huqA:
undetectable		 5n0sB-1huqA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1huq RAB5C
(Mus
musculus) 		4 / 9 HIS A  84
TYR A  91
ILE A  74
LEU A  59
 None
 0.81A 5vkqB-1huqA:
0.0
5vkqC-1huqA:
0.0		 5vkqB-1huqA:
7.17
5vkqC-1huqA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 1huq RAB5C
(Mus
musculus) 		4 / 6 ASN A 172
VAL A  42
LEU A  39
GLN A  61
 None
 1.43A 5xdhA-1huqA:
undetectable
5xdhC-1huqA:
undetectable		 5xdhA-1huqA:
20.38
5xdhC-1huqA:
20.38