SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hwp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 1hwp EBULIN
(Sambucus
ebulus) 		3 / 3 VAL B 185
VAL B 171
TRP B 175
 None
 0.91A 1av2C-1hwpB:
undetectable
1av2D-1hwpB:
undetectable		 1av2C-1hwpB:
7.58
1av2D-1hwpB:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 1hwp EBULIN
(Sambucus
ebulus) 		4 / 7 ARG B 181
THR B 132
VAL B  16
ALA B 127
 None
 1.05A 1fo4B-1hwpB:
undetectable		 1fo4B-1hwpB:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 1hwp EBULIN
(Sambucus
ebulus) 		3 / 3 VAL B 185
VAL B 171
TRP B 175
 None
 0.91A 1w5uC-1hwpB:
undetectable
1w5uD-1hwpB:
undetectable		 1w5uC-1hwpB:
7.58
1w5uD-1hwpB:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 1hwp EBULIN
(Sambucus
ebulus) 		4 / 6 MET B 107
ILE B  15
PRO B 101
SER B 103
 None
 1.49A 2qd3B-1hwpB:
undetectable		 2qd3B-1hwpB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 1hwp EBULIN
(Sambucus
ebulus) 		4 / 5 GLU B 157
ILE B 206
GLY B 156
LYS B 208
 None
 1.08A 2qeuA-1hwpB:
undetectable
2qeuC-1hwpB:
undetectable		 2qeuA-1hwpB:
19.47
2qeuC-1hwpB:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 1hwp EBULIN
(Sambucus
ebulus) 		4 / 6 THR B 252
ASN B 254
ASP B 235
ILE B 247
 None
 1.44A 3w9tB-1hwpB:
16.1		 3w9tB-1hwpB:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1hwp EBULIN
(Sambucus
ebulus) 		5 / 11 SER B  73
LEU B 118
GLN B 129
ALA B 109
PRO B 110
 None
 1.05A 4uuuB-1hwpB:
undetectable		 4uuuB-1hwpB:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 1hwp EBULIN
(Sambucus
ebulus) 		5 / 11 ALA B  83
VAL B  92
ILE B  98
ASN B 100
ILE B  15
 None
 1.32A 5y80A-1hwpB:
undetectable		 5y80A-1hwpB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 1hwp EBULIN
(Sambucus
ebulus) 		5 / 11 ALA B  84
VAL B  92
ILE B  98
ASN B 100
ILE B  15
 None
 1.17A 5y80A-1hwpB:
undetectable		 5y80A-1hwpB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 1hwp EBULIN
(Sambucus
ebulus) 		4 / 9 VAL B 193
LEU B 143
VAL B 171
SER B 170
 None
 1.00A 6c2mD-1hwpB:
undetectable		 6c2mD-1hwpB:
16.15