SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hwu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQG_A_IBPA701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	1hwu	PII PROTEIN (Herbaspirillum seropedicae)	5 / 9	VAL A 63 VAL A 16 LEU A 20 ILE A 91 ALA A 6	None	1.02A	1eqgA-1hwuA: undetectable	1eqgA-1hwuA: 10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQG_B_IBPB1701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	1hwu	PII PROTEIN (Herbaspirillum seropedicae)	5 / 11	VAL A 63 VAL A 16 LEU A 20 ILE A 91 ALA A 6	None	1.04A	1eqgB-1hwuA: undetectable	1eqgB-1hwuA: 10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQH_A_FLPA701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	1hwu	PII PROTEIN (Herbaspirillum seropedicae)	5 / 12	VAL A 63 VAL A 16 LEU A 20 ILE A 91 ALA A 6	None	1.01A	1eqhA-1hwuA: undetectable	1eqhA-1hwuA: 10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQH_B_FLPB1701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	1hwu	PII PROTEIN (Herbaspirillum seropedicae)	5 / 12	VAL A 63 VAL A 16 LEU A 20 ILE A 91 ALA A 6	None	1.03A	1eqhB-1hwuA: undetectable	1eqhB-1hwuA: 10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_A_P1ZA2001_1 (SERUM ALBUMIN)	1hwu	PII PROTEIN (Herbaspirillum seropedicae)	5 / 12	LEU A 28 LEU A 20 ALA A 81 ILE A 8 ALA A 6	None	0.90A	2bxcA-1hwuA: undetectable	2bxcA-1hwuA: 12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L94_A_TESA502_1 (CYTOCHROME P450)	1hwu	PII PROTEIN (Herbaspirillum seropedicae)	5 / 8	VAL A 4 ILE A 77 ALA A 76 VAL A 69 VAL A 70	None	1.22A	5l94A-1hwuA: undetectable	5l94A-1hwuA: 13.17

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EQG_A_IBPA701_1","PROSTAGLANDIN H2 SYNTHASE-1","1hwu","PII PROTEIN","Herbaspirillum seropedicae",5,"VAL A  63;VAL A  16;LEU A  20;ILE A  91;ALA A   6","None","1.02A","1eqgA-1hwuA:undetectable","1eqgA-1hwuA:10.86"],["1EQG_B_IBPB1701_1","PROSTAGLANDIN H2 SYNTHASE-1","1hwu","PII PROTEIN","Herbaspirillum seropedicae",5,"VAL A  63;VAL A  16;LEU A  20;ILE A  91;ALA A   6","None","1.04A","1eqgB-1hwuA:undetectable","1eqgB-1hwuA:10.86"],["1EQH_A_FLPA701_1","PROSTAGLANDIN H2 SYNTHASE-1","1hwu","PII PROTEIN","Herbaspirillum seropedicae",5,"VAL A  63;VAL A  16;LEU A  20;ILE A  91;ALA A   6","None","1.01A","1eqhA-1hwuA:undetectable","1eqhA-1hwuA:10.86"],["1EQH_B_FLPB1701_1","PROSTAGLANDIN H2 SYNTHASE-1","1hwu","PII PROTEIN","Herbaspirillum seropedicae",5,"VAL A  63;VAL A  16;LEU A  20;ILE A  91;ALA A   6","None","1.03A","1eqhB-1hwuA:undetectable","1eqhB-1hwuA:10.86"],["2BXC_A_P1ZA2001_1","SERUM ALBUMIN","1hwu","PII PROTEIN","Herbaspirillum seropedicae",5,"LEU A  28;LEU A  20;ALA A  81;ILE A   8;ALA A   6","None","0.90A","2bxcA-1hwuA:undetectable","2bxcA-1hwuA:12.65"],["5L94_A_TESA502_1","CYTOCHROME P450","1hwu","PII PROTEIN","Herbaspirillum seropedicae",5,"VAL A   4;ILE A  77;ALA A  76;VAL A  69;VAL A  70","None","1.22A","5l94A-1hwuA:undetectable","5l94A-1hwuA:13.17"]]