SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hx6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 1hx6 MAJOR CAPSID PROTEIN
(Salmonella
virus
PRD1) 		4 / 7 PHE A  55
ALA A 197
GLU A 195
VAL A  72
 None
 0.93A 1hk2A-1hx6A:
undetectable		 1hk2A-1hx6A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 1hx6 MAJOR CAPSID PROTEIN
(Salmonella
virus
PRD1) 		3 / 3 TRP A 167
VAL A 168
PRO A 169
 None
 0.82A 1rg1A-1hx6A:
0.0		 1rg1A-1hx6A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 1hx6 MAJOR CAPSID PROTEIN
(Salmonella
virus
PRD1) 		3 / 3 TRP A 167
VAL A 168
PRO A 169
 None
 0.83A 1rh0A-1hx6A:
0.0		 1rh0A-1hx6A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 1hx6 MAJOR CAPSID PROTEIN
(Salmonella
virus
PRD1) 		4 / 7 GLY A 339
ASP A 335
TYR A 341
ARG A 329
 None
 1.01A 3aruA-1hx6A:
undetectable		 3aruA-1hx6A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 1hx6 MAJOR CAPSID PROTEIN
(Salmonella
virus
PRD1) 		4 / 7 PHE A  90
GLY A 339
ASP A 292
ARG A 372
 None
 1.12A 3aruA-1hx6A:
undetectable		 3aruA-1hx6A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 1hx6 MAJOR CAPSID PROTEIN
(Salmonella
virus
PRD1) 		4 / 8 ASN A  24
ILE A 252
PHE A 380
ARG A  28
 None
 1.41A 3ccfB-1hx6A:
undetectable		 3ccfB-1hx6A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_A_FOLA201_0
(FOLATE ECF
TRANSPORTER)		 1hx6 MAJOR CAPSID PROTEIN
(Salmonella
virus
PRD1) 		5 / 12 TYR A 379
PHE A 380
THR A 381
ASN A  24
ARG A  28
 None
None
MPD  A 501 ( 4.7A)
None
None
 1.37A 4z7fA-1hx6A:
0.0		 4z7fA-1hx6A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_B_FOLB201_0
(FOLATE ECF
TRANSPORTER)		 1hx6 MAJOR CAPSID PROTEIN
(Salmonella
virus
PRD1) 		5 / 12 TYR A 379
PHE A 380
THR A 381
ASN A  24
ARG A  28
 None
None
MPD  A 501 ( 4.7A)
None
None
 1.34A 4z7fB-1hx6A:
0.0		 4z7fB-1hx6A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1hx6 MAJOR CAPSID PROTEIN
(Salmonella
virus
PRD1) 		5 / 12 GLY A 114
SER A 131
ILE A 148
PHE A 129
MET A 164
 None
 1.12A 5igwA-1hx6A:
0.0		 5igwA-1hx6A:
20.86