SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hxn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1hxn HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 12 LEU A 233
LEU A 430
SER A 226
SER A 236
PHE A 249
 None
 1.11A 1dfoA-1hxnA:
undetectable		 1dfoA-1hxnA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1hxn HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 12 LEU A 233
LEU A 430
SER A 226
SER A 236
PHE A 249
 None
 1.11A 1dfoB-1hxnA:
undetectable		 1dfoB-1hxnA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1hxn HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 12 LEU A 233
LEU A 430
SER A 226
SER A 236
PHE A 249
 None
 1.11A 1dfoC-1hxnA:
undetectable		 1dfoC-1hxnA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1hxn HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 12 LEU A 233
LEU A 430
SER A 226
SER A 236
PHE A 249
 None
 1.11A 1dfoD-1hxnA:
undetectable		 1dfoD-1hxnA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1hxn HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 12 LEU A 233
LEU A 430
SER A 226
SER A 236
PHE A 249
 None
 1.14A 1eqbA-1hxnA:
undetectable		 1eqbA-1hxnA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1hxn HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 12 LEU A 233
LEU A 430
SER A 226
SER A 236
PHE A 249
 None
 1.14A 1eqbB-1hxnA:
undetectable		 1eqbB-1hxnA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1hxn HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 12 LEU A 233
LEU A 430
SER A 226
SER A 236
PHE A 249
 None
 1.13A 1eqbC-1hxnA:
undetectable		 1eqbC-1hxnA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1hxn HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 12 LEU A 233
LEU A 430
SER A 226
SER A 236
PHE A 249
 None
 1.14A 1eqbD-1hxnA:
undetectable		 1eqbD-1hxnA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 1hxn HEMOPEXIN
(Oryctolagus
cuniculus) 		4 / 8 VAL A 411
HIS A 345
LEU A 352
TRP A 354
 None
 1.13A 1pk2A-1hxnA:
undetectable		 1pk2A-1hxnA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 1hxn HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 9 GLY A 312
VAL A 310
PRO A 314
GLU A 318
TYR A 299
 None
 1.27A 4fimA-1hxnA:
undetectable		 4fimA-1hxnA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1hxn HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 12 ILE A 293
LEU A 317
VAL A 239
LEU A 290
PHE A 284
 None
None
PO4  A   1 ( 4.2A)
None
None
 1.08A 4y0qA-1hxnA:
0.0		 4y0qA-1hxnA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1hxn HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 12 LEU A 355
ILE A 293
LEU A 317
LEU A 290
PHE A 284
 None
 1.12A 4y0qA-1hxnA:
0.0		 4y0qA-1hxnA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1hxn HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 8 ALA A 282
LEU A 317
LEU A 329
LEU A 344
LEU A 321
 CL  A   3 ( 4.0A)
None
None
None
None
 1.23A 5jqbA-1hxnA:
undetectable
5jqbB-1hxnA:
undetectable		 5jqbA-1hxnA:
20.43
5jqbB-1hxnA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1hxn HEMOPEXIN
(Oryctolagus
cuniculus) 		5 / 8 ALA A 335
LEU A 317
LEU A 329
LEU A 355
LEU A 321
 CL  A   3 ( 4.7A)
None
None
None
None
 1.45A 5jqbA-1hxnA:
undetectable
5jqbB-1hxnA:
undetectable		 5jqbA-1hxnA:
20.43
5jqbB-1hxnA:
19.56