SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hy5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 1hy5 YERSINIA PESTIS
VIRULENCE PROTEIN
YOPE
(Yersinia
pestis) 		3 / 3 PHE A1178
LEU A1143
MET A1128
 None
 0.84A 1mx1D-1hy5A:
undetectable		 1mx1D-1hy5A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1hy5 YERSINIA PESTIS
VIRULENCE PROTEIN
YOPE
(Yersinia
pestis) 		4 / 5 GLY A1182
THR A1183
HIS A1133
SER A1189
 None
 0.91A 6jmjA-1hy5A:
undetectable		 6jmjA-1hy5A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1hy5 YERSINIA PESTIS
VIRULENCE PROTEIN
YOPE
(Yersinia
pestis) 		4 / 7 GLY A1182
THR A1183
HIS A1133
SER A1189
 None
 0.91A 6jnhA-1hy5A:
undetectable		 6jnhA-1hy5A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1hy5 YERSINIA PESTIS
VIRULENCE PROTEIN
YOPE
(Yersinia
pestis) 		4 / 6 GLY A1182
THR A1183
HIS A1133
SER A1189
 None
 0.90A 6jogA-1hy5A:
undetectable		 6jogA-1hy5A:
19.89