SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hyl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 10 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.99A 1hsgA-1hylA:
undetectable		 1hsgA-1hylA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.94A 1hxbB-1hylA:
undetectable		 1hxbB-1hylA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 GLY A  44
SER A  45
LEU A 209
ILE A  47
ILE A 108
 None
 1.24A 1kyvA-1hylA:
undetectable
1kyvE-1hylA:
undetectable		 1kyvA-1hylA:
23.08
1kyvE-1hylA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 ILE A 108
GLY A  44
SER A  45
LEU A 209
ILE A  47
 None
 1.23A 1kyvB-1hylA:
undetectable
1kyvC-1hylA:
undetectable		 1kyvB-1hylA:
23.08
1kyvC-1hylA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 ILE A 108
GLY A  44
SER A  45
LEU A 209
ILE A  47
 None
 1.23A 1kyvC-1hylA:
undetectable
1kyvD-1hylA:
undetectable		 1kyvC-1hylA:
23.08
1kyvD-1hylA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 ILE A 108
GLY A  44
SER A  45
LEU A 209
ILE A  47
 None
 1.21A 1kyvD-1hylA:
undetectable
1kyvE-1hylA:
undetectable		 1kyvD-1hylA:
23.08
1kyvE-1hylA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		4 / 8 ASP A 102
PHE A  94
SER A 195
ALA A 104
 None
 1.01A 1rqpC-1hylA:
undetectable		 1rqpC-1hylA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		4 / 8 ASP A 102
PHE A  94
SER A 195
ALA A 104
 None
 1.00A 1rqpA-1hylA:
undetectable		 1rqpA-1hylA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		4 / 7 ILE A  88
LEU A 123
ILE A 121
ASP A  48
 None
 0.86A 1uwjA-1hylA:
undetectable		 1uwjA-1hylA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_2
(HIV-1 PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 GLY A  44
ALA A  31
ILE A 118
ILE A  47
VAL A  66
 None
 0.83A 2b7zB-1hylA:
undetectable		 2b7zB-1hylA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		4 / 8 GLY A  76
ALA A  81
ASN A 117
ILE A 118
 None
 0.86A 2dtjA-1hylA:
undetectable
2dtjB-1hylA:
undetectable		 2dtjA-1hylA:
18.88
2dtjB-1hylA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.98A 2f80B-1hylA:
undetectable		 2f80B-1hylA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.93A 2f81B-1hylA:
undetectable		 2f81B-1hylA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 HIS A  59
ALA A 104
ALA A  31
GLY A 197
TRP A  41
 None
 1.18A 2igtC-1hylA:
undetectable		 2igtC-1hylA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.81A 2o4lA-1hylA:
undetectable		 2o4lA-1hylA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 9 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.90A 2o4pB-1hylA:
undetectable		 2o4pB-1hylA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 GLY A  44
GLY A 197
GLY A 193
TRP A  41
ILE A  52
 None
 0.92A 2oxtC-1hylA:
undetectable		 2oxtC-1hylA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
LEU A  53
 None
 1.45A 2oxtD-1hylA:
undetectable		 2oxtD-1hylA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		4 / 8 ASP A 102
PHE A  94
SER A 195
ALA A 104
 None
 1.01A 2v7uA-1hylA:
undetectable		 2v7uA-1hylA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		4 / 8 ILE A 181
GLY A 211
LEU A 209
LEU A 123
 None
 0.78A 2vctA-1hylA:
undetectable		 2vctA-1hylA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		4 / 8 ILE A 181
GLY A 211
LEU A 209
LEU A 123
 None
 0.79A 2vctB-1hylA:
undetectable		 2vctB-1hylA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		4 / 8 ILE A 181
GLY A 211
LEU A 209
LEU A 123
 None
 0.79A 2vctC-1hylA:
0.0		 2vctC-1hylA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 ILE A 121
GLY A  44
GLY A 197
ASP A 194
TYR A  29
 None
 1.20A 2zw9A-1hylA:
undetectable		 2zw9A-1hylA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.79A 3bvbB-1hylA:
undetectable		 3bvbB-1hylA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 10 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.90A 3em3A-1hylA:
undetectable		 3em3A-1hylA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 123
GLY A 243
ILE A  89
ARG A  87
LEU A  53
 None
 1.13A 3ijdB-1hylA:
undetectable		 3ijdB-1hylA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.91A 3jvyB-1hylA:
undetectable		 3jvyB-1hylA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.85A 3k4vA-1hylA:
undetectable		 3k4vA-1hylA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.96A 3k4vC-1hylA:
undetectable		 3k4vC-1hylA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.93A 3k4vD-1hylA:
undetectable		 3k4vD-1hylA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 10 VAL A 212
LEU A 209
SER A 229
GLY A 196
GLY A  44
 None
 1.07A 3ls4H-1hylA:
undetectable		 3ls4H-1hylA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.93A 3ndtD-1hylA:
undetectable		 3ndtD-1hylA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.87A 3nduA-1hylA:
undetectable		 3nduA-1hylA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.90A 3nduB-1hylA:
undetectable		 3nduB-1hylA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.94A 3nduD-1hylA:
undetectable		 3nduD-1hylA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_1
(FIV PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 10 LEU A 209
ALA A 136
ILE A 134
GLY A 183
VAL A 231
 None
 1.02A 3ogpA-1hylA:
1.3		 3ogpA-1hylA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 9 LEU A 209
ALA A 136
GLY A 183
VAL A 226
ILE A 210
 None
 0.96A 3oxvA-1hylA:
undetectable		 3oxvA-1hylA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 9 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.95A 3oxvA-1hylA:
undetectable		 3oxvA-1hylA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 10 LEU A 209
ALA A 136
GLY A 183
VAL A 226
ILE A 210
 None
 0.93A 3oxwB-1hylA:
undetectable		 3oxwB-1hylA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 10 LEU A 209
ALA A 136
GLY A 183
VAL A 226
ILE A 210
 None
 0.94A 3oxwD-1hylA:
undetectable		 3oxwD-1hylA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.97A 3pwrA-1hylA:
undetectable		 3pwrA-1hylA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.92A 3tkgA-1hylA:
undetectable		 3tkgA-1hylA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.87A 3tkgB-1hylA:
undetectable		 3tkgB-1hylA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 10 TRP A  41
GLY A  76
VAL A  65
ASP A  34
VAL A  66
 None
 1.20A 4c9pB-1hylA:
0.0		 4c9pB-1hylA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 10 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.88A 4dqfB-1hylA:
undetectable		 4dqfB-1hylA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		4 / 5 GLN A 239
THR A 242
LEU A 209
LEU A 123
 None
 1.07A 4lvcB-1hylA:
undetectable		 4lvcB-1hylA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		4 / 6 ILE A  35
GLY A  44
VAL A 212
HIS A  57
 None
 0.84A 4oltA-1hylA:
0.0		 4oltA-1hylA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		4 / 6 ILE A  35
GLY A  44
VAL A 212
HIS A  57
 None
 0.86A 4oltB-1hylA:
0.0		 4oltB-1hylA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 11 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.87A 4qgiB-1hylA:
undetectable		 4qgiB-1hylA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 9 PRO A 198
LEU A  33
GLY A  32
LEU A  53
THR A  54
 None
 1.17A 4x3mB-1hylA:
undetectable		 4x3mB-1hylA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 10 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 1.06A 5kr1A-1hylA:
undetectable		 5kr1A-1hylA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 11 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.99A 5kr2B-1hylA:
undetectable		 5kr2B-1hylA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		4 / 4 GLN A 239
THR A 242
LEU A 209
LEU A 123
 None
 1.04A 5m5kB-1hylA:
undetectable		 5m5kB-1hylA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 GLY A 196
SER A 189
ILE A  17
GLY A 193
GLY A 142
 None
 0.90A 5zhmB-1hylA:
undetectable		 5zhmB-1hylA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.89A 6difB-1hylA:
undetectable		 6difB-1hylA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 1hyl HYPODERMA LINEATUM
COLLAGENASE
(Hypoderma
lineatum) 		5 / 12 LEU A 209
ALA A 136
GLY A 183
VAL A 231
ILE A 210
 None
 0.83A 6dilB-1hylA:
undetectable		 6dilB-1hylA:
20.39