SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hzh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 1hzh IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 VAL H 102
TRP H 103
ASN H 100
GLY H  96
 None
 1.13A 3kmoB-1hzhH:
undetectable		 3kmoB-1hzhH:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 1hzh IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 SER H 280
TYR H 319
SER H 317
GLU H 282
 None
 1.26A 4xzkA-1hzhH:
undetectable		 4xzkA-1hzhH:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 1hzh IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		4 / 6 SER H  30
GLY H  55
ASN H  54
ILE H  34
 None
 1.04A 5j4nA-1hzhH:
undetectable		 5j4nA-1hzhH:
20.89