SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hzm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1hzm DUAL SPECIFICITY
PROTEIN PHOSPHATASE
6
(Homo
sapiens) 		5 / 12 GLY A 126
CYH A 127
LEU A  97
LEU A 119
TYR A 131
 None
 1.39A 1fm6D-1hzmA:
undetectable		 1fm6D-1hzmA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 1hzm DUAL SPECIFICITY
PROTEIN PHOSPHATASE
6
(Homo
sapiens) 		3 / 3 PHE A  86
LEU A 122
LEU A 118
 None
 0.60A 1mx1E-1hzmA:
undetectable		 1mx1E-1hzmA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1hzm DUAL SPECIFICITY
PROTEIN PHOSPHATASE
6
(Homo
sapiens) 		5 / 12 GLY A 126
CYH A 127
LEU A  97
LEU A 119
TYR A 131
 None
 1.40A 4emaA-1hzmA:
undetectable		 4emaA-1hzmA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1hzm DUAL SPECIFICITY
PROTEIN PHOSPHATASE
6
(Homo
sapiens) 		3 / 3 LEU A  71
PRO A  72
ARG A  40
 None
 0.72A 4klrB-1hzmA:
undetectable		 4klrB-1hzmA:
18.11