SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1hzo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		7 / 12 ALA A  69
SER A  70
LYS A  73
SER A 130
ASN A 132
LYS A 234
GLY A 236
 None
MES  A1000 (-3.1A)
None
MES  A1000 (-2.7A)
None
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
 0.39A 1ghmA-1hzoA:
38.3		 1ghmA-1hzoA:
33.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 12 ALA A  69
SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
THR A 216
LYS A 234
GLY A 236
 None
MES  A1000 (-3.1A)
None
MES  A1000 (-2.7A)
None
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
 0.49A 1i2wA-1hzoA:
41.6		 1i2wA-1hzoA:
43.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		4 / 5 TYR A 105
PRO A 167
LEU A 169
THR A 235
 MES  A1000 (-3.9A)
None
None
MES  A1000 (-3.7A)
 0.57A 1i2wA-1hzoA:
41.6		 1i2wA-1hzoA:
43.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 ALA A  69
SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
THR A 216
GLY A 236
 None
MES  A1000 (-3.1A)
None
MES  A1000 (-2.7A)
None
None
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
 0.49A 1i2wB-1hzoA:
41.7		 1i2wB-1hzoA:
43.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		4 / 7 THR A 244
SER A 237
TYR A  39
LEU A  36
 None
MES  A1000 (-2.7A)
None
None
 1.16A 1ibgL-1hzoA:
0.0		 1ibgL-1hzoA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		5 / 10 LYS A  82
GLU A  85
ALA A  78
ALA A 192
LEU A 190
 None
 1.23A 1ie4A-1hzoA:
0.0
1ie4C-1hzoA:
0.0		 1ie4A-1hzoA:
21.57
1ie4C-1hzoA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		5 / 8 ALA A 192
LEU A 190
LYS A  82
GLU A  85
ALA A  78
 None
 1.28A 1ie4B-1hzoA:
undetectable
1ie4D-1hzoA:
undetectable		 1ie4B-1hzoA:
21.57
1ie4D-1hzoA:
21.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		11 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
ASN A 170
THR A 216
LYS A 234
GLY A 236
GLY A 238
ASP A 240
 MES  A1000 (-3.1A)
None
MES  A1000 (-2.7A)
None
None
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
None
None
 0.51A 1ymxA-1hzoA:
46.6		 1ymxA-1hzoA:
65.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		11 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
ASN A 170
LYS A 234
GLY A 236
SER A 237
GLY A 238
ASP A 240
 MES  A1000 (-3.1A)
None
MES  A1000 (-2.7A)
None
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
None
 0.58A 1ymxB-1hzoA:
46.7		 1ymxB-1hzoA:
65.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		4 / 5 TYR A 105
PRO A 167
THR A 216
THR A 235
 MES  A1000 (-3.9A)
None
MES  A1000 (-3.7A)
MES  A1000 (-3.7A)
 0.24A 1ymxB-1hzoA:
46.7		 1ymxB-1hzoA:
65.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		4 / 8 ILE A 247
SER A 130
TYR A 264
SER A  72
 None
MES  A1000 (-2.7A)
None
None
 1.00A 2zw9B-1hzoA:
undetectable		 2zw9B-1hzoA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_2
(PROTEASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		5 / 10 LEU A 259
ASP A 233
VAL A 231
GLY A 224
ILE A 250
 None
 0.93A 3em3B-1hzoA:
undetectable		 3em3B-1hzoA:
19.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 12 LYS A  73
TYR A 105
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
GLY A 236
GLY A 238
 None
MES  A1000 (-3.9A)
MES  A1000 (-2.7A)
None
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
None
 0.65A 3hlwA-1hzoA:
46.3		 3hlwA-1hzoA:
65.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
GLY A 236
SER A 237
GLY A 238
 MES  A1000 (-2.7A)
None
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
 0.62A 3hlwA-1hzoA:
46.3		 3hlwA-1hzoA:
65.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 12 SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
SER A 237
GLY A 238
 MES  A1000 (-2.7A)
None
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
 0.59A 3hlwB-1hzoA:
46.4		 3hlwB-1hzoA:
65.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 12 TYR A 105
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
GLY A 238
 MES  A1000 (-3.9A)
MES  A1000 (-2.7A)
None
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
 0.57A 3hlwB-1hzoA:
46.4		 3hlwB-1hzoA:
65.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 12 LYS A  73
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
SER A 237
GLY A 238
ASP A 240
 None
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
None
 0.72A 3huoA-1hzoA:
46.4		 3huoA-1hzoA:
65.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		5 / 6 THR A  51
LEU A 195
GLY A 196
ALA A 257
PRO A 258
 None
 0.32A 3huoA-1hzoA:
46.4		 3huoA-1hzoA:
65.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 LYS A  73
ASN A 132
ASN A 170
LYS A 234
GLY A 236
SER A 237
GLY A 238
ASP A 240
 None
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
None
 0.72A 3huoB-1hzoA:
46.5		 3huoB-1hzoA:
65.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		6 / 12 ALA A  69
SER A  70
LYS A  73
ASN A 132
THR A 235
GLY A 236
 None
MES  A1000 (-3.1A)
None
None
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
 0.49A 3mzeA-1hzoA:
21.7		 3mzeA-1hzoA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		5 / 9 THR A 287
GLN A  32
GLU A 284
LEU A  48
ILE A  57
 None
 1.37A 3nbqA-1hzoA:
undetectable		 3nbqA-1hzoA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
GLY A 238
ASP A 240
 MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
None
 0.53A 3ny4A-1hzoA:
40.6		 3ny4A-1hzoA:
42.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		5 / 10 THR A 159
GLY A  45
TYR A 264
ALA A 185
LYS A 188
 None
 1.33A 3pp7B-1hzoA:
undetectable		 3pp7B-1hzoA:
19.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		7 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
GLY A 236
SER A 237
GLY A 238
 None
MES  A1000 (-2.7A)
None
None
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
 0.74A 3q07A-1hzoA:
46.4		 3q07A-1hzoA:
65.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
GLY A 238
ASP A 240
 None
MES  A1000 (-2.7A)
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
None
None
 0.56A 3q07A-1hzoA:
46.4		 3q07A-1hzoA:
65.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		6 / 12 LYS A  73
SER A 130
THR A 171
ASN A 170
LYS A 234
GLY A 236
 None
MES  A1000 (-2.7A)
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
 1.45A 3q07A-1hzoA:
46.4		 3q07A-1hzoA:
65.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		4 / 5 TYR A 105
PRO A 167
THR A 171
THR A 235
 MES  A1000 (-3.9A)
None
None
MES  A1000 (-3.7A)
 0.39A 3q07A-1hzoA:
46.4		 3q07A-1hzoA:
65.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
SER A 237
GLY A 238
ASP A 240
 None
MES  A1000 (-2.7A)
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
None
 0.58A 3q07B-1hzoA:
46.5		 3q07B-1hzoA:
65.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		7 / 12 LYS A  73
SER A 130
THR A 171
ASN A 170
LYS A 234
GLY A 236
SER A 237
 None
MES  A1000 (-2.7A)
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
 1.44A 3q07B-1hzoA:
46.5		 3q07B-1hzoA:
65.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		4 / 5 TYR A 105
PRO A 167
THR A 171
THR A 235
 MES  A1000 (-3.9A)
None
None
MES  A1000 (-3.7A)
 0.33A 3q07B-1hzoA:
46.5		 3q07B-1hzoA:
65.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 ALA A  69
SER A  70
TYR A 105
SER A 130
ASN A 132
LYS A 234
THR A 235
GLY A 236
 None
MES  A1000 (-3.1A)
MES  A1000 (-3.9A)
MES  A1000 (-2.7A)
None
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
 0.22A 3sh8A-1hzoA:
40.3		 3sh8A-1hzoA:
42.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 ALA A  69
SER A  70
LYS A  73
SER A 130
ASN A 132
LYS A 234
GLY A 236
TYR A 274
 None
MES  A1000 (-3.1A)
None
MES  A1000 (-2.7A)
None
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
None
 0.85A 3sh8B-1hzoA:
40.0		 3sh8B-1hzoA:
42.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 None
MES  A1000 (-2.7A)
None
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
 0.47A 4euzA-1hzoA:
42.9		 4euzA-1hzoA:
48.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		6 / 10 SER A 130
ASN A 132
LYS A 234
THR A 235
GLY A 236
ALA A  69
 MES  A1000 (-2.7A)
None
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
 1.49A 4fh2A-1hzoA:
36.2		 4fh2A-1hzoA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		6 / 10 TYR A 105
SER A 130
ASN A 132
LYS A 234
THR A 235
GLY A 236
 MES  A1000 (-3.9A)
MES  A1000 (-2.7A)
None
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
 0.56A 4fh2A-1hzoA:
36.2		 4fh2A-1hzoA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 12 ALA A  69
SER A  70
TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
MES  A1000 (-3.1A)
MES  A1000 (-3.9A)
MES  A1000 (-2.7A)
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
 0.27A 4n9kA-1hzoA:
42.1		 4n9kA-1hzoA:
41.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 ALA A  69
SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
 0.25A 4n9kB-1hzoA:
41.9		 4n9kB-1hzoA:
41.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 ALA A  69
SER A  70
SER A 130
ASN A 132
LYS A 234
THR A 235
GLY A 236
TYR A 274
 None
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
 0.84A 4n9kB-1hzoA:
41.9		 4n9kB-1hzoA:
41.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 12 TYR A 105
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
SER A 237
GLY A 238
 MES  A1000 (-3.9A)
None
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
 0.53A 4pm5A-1hzoA:
46.7		 4pm5A-1hzoA:
65.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 12 TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
SER A 237
GLY A 238
 MES  A1000 (-3.9A)
MES  A1000 (-2.7A)
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
 0.74A 4pm5A-1hzoA:
46.7		 4pm5A-1hzoA:
65.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 LYS A  73
TYR A 105
ASN A 132
ASN A 170
THR A 216
LYS A 234
GLY A 236
GLY A 238
 None
MES  A1000 (-3.9A)
None
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
None
 0.54A 4pm7A-1hzoA:
46.7		 4pm7A-1hzoA:
65.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 LYS A  73
TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
GLY A 238
 None
MES  A1000 (-3.9A)
MES  A1000 (-2.7A)
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
None
 0.73A 4pm7A-1hzoA:
46.7		 4pm7A-1hzoA:
65.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 TYR A 105
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
GLY A 238
 MES  A1000 (-3.9A)
None
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
 0.43A 4pm9A-1hzoA:
46.7		 4pm9A-1hzoA:
66.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		7 / 12 TYR A 105
SER A 130
ASN A 170
LYS A 234
THR A 235
GLY A 236
GLY A 238
 MES  A1000 (-3.9A)
MES  A1000 (-2.7A)
None
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
 0.71A 4pm9A-1hzoA:
46.7		 4pm9A-1hzoA:
66.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		4 / 7 LYS A 137
LEU A 139
GLY A 143
GLY A 144
 None
 0.85A 5a06C-1hzoA:
undetectable		 5a06C-1hzoA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		4 / 7 LYS A 137
LEU A 139
GLY A 143
GLY A 144
 None
 0.86A 5a06E-1hzoA:
undetectable		 5a06E-1hzoA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		4 / 7 LYS A 137
LEU A 139
GLY A 143
GLY A 144
 None
 0.85A 5a06F-1hzoA:
undetectable		 5a06F-1hzoA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		4 / 4 VAL A  80
ALA A 120
ILE A  95
THR A 118
 None
 1.15A 5e4dB-1hzoA:
0.0		 5e4dB-1hzoA:
21.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		7 / 12 ALA A  69
SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
 0.27A 5ghyA-1hzoA:
41.9		 5ghyA-1hzoA:
41.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		7 / 12 ALA A  69
SER A  70
SER A 130
ASN A 132
LYS A 234
GLY A 236
TYR A 274
 None
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
None
 0.82A 5ghyA-1hzoA:
41.9		 5ghyA-1hzoA:
41.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		7 / 12 ALA A  69
SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
 0.24A 5ghyB-1hzoA:
41.9		 5ghyB-1hzoA:
41.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		7 / 12 ALA A  69
SER A  70
SER A 130
ASN A 132
LYS A 234
GLY A 236
TYR A 274
 None
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
None
 0.77A 5ghyB-1hzoA:
41.9		 5ghyB-1hzoA:
41.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 11 ALA A  69
SER A  70
TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
MES  A1000 (-3.1A)
MES  A1000 (-3.9A)
MES  A1000 (-2.7A)
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
 0.28A 5ghzA-1hzoA:
42.0		 5ghzA-1hzoA:
41.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 10 ALA A  69
SER A  70
TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
MES  A1000 (-3.1A)
MES  A1000 (-3.9A)
MES  A1000 (-2.7A)
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
 0.27A 5ghzB-1hzoA:
42.1		 5ghzB-1hzoA:
41.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		3 / 3 THR A 181
SER A 182
TYR A 264
 None
 0.69A 5jsdA-1hzoA:
0.0		 5jsdA-1hzoA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		3 / 3 THR A 181
SER A 182
TYR A 264
 None
 0.69A 5jsdB-1hzoA:
0.0		 5jsdB-1hzoA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		3 / 3 THR A 181
SER A 182
TYR A 264
 None
 0.69A 5jsdC-1hzoA:
0.0		 5jsdC-1hzoA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		3 / 3 THR A 181
SER A 182
TYR A 264
 None
 0.70A 5jseA-1hzoA:
0.0		 5jseA-1hzoA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		3 / 3 THR A 181
SER A 182
TYR A 264
 None
 0.70A 5jseB-1hzoA:
0.0		 5jseB-1hzoA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		3 / 3 THR A 181
SER A 182
TYR A 264
 None
 0.71A 5jseC-1hzoA:
0.0		 5jseC-1hzoA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		5 / 10 ILE A  29
ILE A  57
GLU A  52
ASP A  53
ILE A 290
 None
 1.27A 5lg3F-1hzoA:
0.0		 5lg3F-1hzoA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		5 / 10 ILE A  29
ILE A  57
GLU A  52
ASP A  53
ILE A 290
 None
 1.21A 5lg3G-1hzoA:
0.1		 5lg3G-1hzoA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		5 / 10 ILE A  29
ILE A  57
GLU A  52
ASP A  53
ILE A 290
 None
 1.20A 5lg3H-1hzoA:
0.0		 5lg3H-1hzoA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		5 / 12 ILE A  29
ILE A  57
GLU A  52
ASP A  53
ILE A 290
 None
 1.21A 5lg3J-1hzoA:
0.0		 5lg3J-1hzoA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		5 / 9 PRO A 107
TYR A 129
THR A 215
THR A 216
ASP A 240
 None
None
None
MES  A1000 (-3.7A)
None
 0.71A 6b5yA-1hzoA:
41.1
6b5yB-1hzoA:
41.2		 6b5yA-1hzoA:
22.58
6b5yB-1hzoA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
GLY A 238
ASP A 240
 MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
None
 0.54A 6b5yB-1hzoA:
41.2		 6b5yB-1hzoA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
GLY A 238
ASP A 240
 MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
None
 0.56A 6b5yD-1hzoA:
41.3		 6b5yD-1hzoA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		5 / 9 PRO A 107
TYR A 129
THR A 215
THR A 216
ASP A 240
 None
None
None
MES  A1000 (-3.7A)
None
 0.71A 6b68A-1hzoA:
41.3
6b68B-1hzoA:
41.4		 6b68A-1hzoA:
22.58
6b68B-1hzoA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
GLY A 238
ASP A 240
 MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
None
 0.46A 6b68B-1hzoA:
41.4		 6b68B-1hzoA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
GLY A 236
GLY A 238
ASP A 240
 MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
None
None
 0.51A 6b68D-1hzoA:
41.3		 6b68D-1hzoA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		5 / 9 PRO A 107
TYR A 129
THR A 215
THR A 216
ASP A 240
 None
None
None
MES  A1000 (-3.7A)
None
 0.72A 6b69A-1hzoA:
41.2
6b69B-1hzoA:
41.3		 6b69A-1hzoA:
22.58
6b69B-1hzoA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		10 / 12 SER A  70
SER A 130
PRO A 167
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
GLY A 238
ASP A 240
 MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
None
 0.46A 6b69A-1hzoA:
41.2
6b69B-1hzoA:
41.3		 6b69A-1hzoA:
22.58
6b69B-1hzoA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_C_9F2C302_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		5 / 9 PRO A 107
TYR A 129
THR A 215
THR A 216
ASP A 240
 None
None
None
MES  A1000 (-3.7A)
None
 0.70A 6b69C-1hzoA:
41.3
6b69D-1hzoA:
41.3		 6b69C-1hzoA:
22.58
6b69D-1hzoA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
GLY A 238
 MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
 0.32A 6b69D-1hzoA:
41.3		 6b69D-1hzoA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
GLY A 238
ASP A 240
 MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
None
 0.49A 6b6aB-1hzoA:
41.3		 6b6aB-1hzoA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 SER A  70
SER A 130
ASN A 170
LYS A 234
THR A 235
GLY A 236
GLY A 238
ASP A 240
 MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
None
 0.38A 6b6aD-1hzoA:
41.3		 6b6aD-1hzoA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 SER A  70
SER A 130
PRO A 167
ASN A 170
LYS A 234
THR A 235
GLY A 236
GLY A 238
 MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
 0.31A 6b6cA-1hzoA:
41.1		 6b6cA-1hzoA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		7 / 12 SER A  70
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
GLY A 238
 MES  A1000 (-3.1A)
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
 0.37A 6b6dA-1hzoA:
40.8		 6b6dA-1hzoA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		7 / 12 SER A  70
SER A 130
ASN A 170
LYS A 234
THR A 235
GLY A 236
GLY A 238
 MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
 0.58A 6b6dA-1hzoA:
40.8		 6b6dA-1hzoA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		8 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
GLY A 238
 MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
 0.33A 6b6eA-1hzoA:
41.1		 6b6eA-1hzoA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 12 SER A  70
SER A 130
PRO A 167
ASN A 170
LYS A 234
THR A 235
GLY A 236
GLY A 238
ASP A 240
 MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
None
MES  A1000 (-2.9A)
MES  A1000 (-3.7A)
MES  A1000 (-3.1A)
None
None
 0.43A 6b6fA-1hzoA:
40.8		 6b6fA-1hzoA:
22.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		9 / 12 TYR A 105
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
GLY A 236
SER A 237
GLY A 238
 MES  A1000 (-3.9A)
MES  A1000 (-2.7A)
None
None
MES  A1000 (-3.7A)
MES  A1000 (-2.9A)
MES  A1000 (-3.1A)
MES  A1000 (-2.7A)
None
 0.59A 6c79A-1hzoA:
46.6		 6c79A-1hzoA:
62.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 1hzo BETA-LACTAMASE
(Proteus
vulgaris) 		4 / 8 LEU A 119
LEU A  90
LEU A 139
GLY A 144
 None
 0.95A 6ce2A-1hzoA:
undetectable		 6ce2A-1hzoA:
13.28