SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1i0r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SG9_C_SAMC303_0 (HEMK PROTEIN)	1i0r	CONSERVED HYPOTHETICAL PROTEIN (Archaeoglobus fulgidus)	5 / 12	ILE A 42 GLY A 63 ALA A 61 VAL A 66 SER A 65	None	1.07A	1sg9C-1i0rA: undetectable	1sg9C-1i0rA: 21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EIX_A_NIMA201_1 (PHOSPHOLIPASE A2 VRV-PL-VIIIA)	1i0r	CONSERVED HYPOTHETICAL PROTEIN (Archaeoglobus fulgidus)	4 / 4	LEU A 104 ALA A 115 ILE A 113 LYS A 96	None	1.42A	4eixA-1i0rA: 0.0	4eixA-1i0rA: 20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_A_ACTA505_0 (RNA POLYMERASE 3D-POL)	1i0r	CONSERVED HYPOTHETICAL PROTEIN (Archaeoglobus fulgidus)	3 / 3	CYH A 25 ASN A 54 LYS A 83	None None FMN A2000 (-4.4A)	1.40A	4k50A-1i0rA: undetectable	4k50A-1i0rA: 15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I8F_A_ML1A211_1 (PHENOLIC OXIDATIVE COUPLING PROTEIN)	1i0r	CONSERVED HYPOTHETICAL PROTEIN (Archaeoglobus fulgidus)	4 / 6	VAL A 32 ALA A 29 GLN A 27 VAL A 16	None FMN A2000 (-3.7A) FMN A2000 (-3.6A) None	1.05A	5i8fA-1i0rA: 0.0	5i8fA-1i0rA: 22.28

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1SG9_C_SAMC303_0","HEMK PROTEIN","1i0r","CONSERVED HYPOTHETICAL PROTEIN","Archaeoglobus fulgidus",5,"ILE A  42;GLY A  63;ALA A  61;VAL A  66;SER A  65","None","1.07A","1sg9C-1i0rA:undetectable","1sg9C-1i0rA:21.83"],["4EIX_A_NIMA201_1","PHOSPHOLIPASE A2 VRV-PL-VIIIA","1i0r","CONSERVED HYPOTHETICAL PROTEIN","Archaeoglobus fulgidus",4,"LEU A 104;ALA A 115;ILE A 113;LYS A  96","None","1.42A","4eixA-1i0rA:0.0","4eixA-1i0rA:20.79"],["4K50_A_ACTA505_0","RNA POLYMERASE 3D-POL","1i0r","CONSERVED HYPOTHETICAL PROTEIN","Archaeoglobus fulgidus",3,"CYH A  25;ASN A  54;LYS A  83","None;None;FMN A2000 (-4.4A)","1.40A","4k50A-1i0rA:undetectable","4k50A-1i0rA:15.15"],["5I8F_A_ML1A211_1","PHENOLIC OXIDATIVE COUPLING PROTEIN","1i0r","CONSERVED HYPOTHETICAL PROTEIN","Archaeoglobus fulgidus",4,"VAL A  32;ALA A  29;GLN A  27;VAL A  16","None;FMN A2000 (-3.7A);FMN A2000 (-3.6A);None","1.05A","5i8fA-1i0rA:0.0","5i8fA-1i0rA:22.28"]]