SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1i17'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KNY_B_KANB559_1 (KANAMYCIN NUCLEOTIDYLTRANSFERA SE)	1i17	PRION-LIKE PROTEIN (Mus musculus)	4 / 8	LYS A 12 SER A 78 ASP A 77 GLU A 74	None	0.92A	1knyA-1i17A: undetectable 1knyB-1i17A: 0.0	1knyA-1i17A: 20.56 1knyB-1i17A: 20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KNY_B_KANB559_1 (KANAMYCIN NUCLEOTIDYLTRANSFERA SE)	1i17	PRION-LIKE PROTEIN (Mus musculus)	4 / 8	SER A 78 ASP A 77 GLU A 74 GLU A 70	None	1.15A	1knyA-1i17A: undetectable 1knyB-1i17A: 0.0	1knyA-1i17A: 20.56 1knyB-1i17A: 20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M9Q_B_BEZB251_0 (SERINE PROTEASE INHIBITOR SERINE PROTEASE SUBUNIT NS2B, SERINE PROTEASE NS3)	1i17	PRION-LIKE PROTEIN (Mus musculus)	5 / 9	LEU A 88 ILE A 89 ILE A 40 PHE A 71 LEU A 85	None	1.15A	2m9qA-1i17A: undetectable	2m9qA-1i17A: 20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZM9_A_ACAA502_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	1i17	PRION-LIKE PROTEIN (Mus musculus)	4 / 8	ALA A 62 TRP A 86 GLY A 8 ILE A 40	None	0.85A	2zm9A-1i17A: undetectable	2zm9A-1i17A: 11.36

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1KNY_B_KANB559_1","KANAMYCIN NUCLEOTIDYLTRANSFERASE;KANAMYCIN NUCLEOTIDYLTRANSFERASE","1i17","PRION-LIKE PROTEIN","Mus musculus",4,"LYS A  12;SER A  78;ASP A  77;GLU A  74","None","0.92A","1knyA-1i17A:undetectable;1knyB-1i17A:0.0","1knyA-1i17A:20.56;1knyB-1i17A:20.56"],["1KNY_B_KANB559_1","KANAMYCIN NUCLEOTIDYLTRANSFERASE;KANAMYCIN NUCLEOTIDYLTRANSFERASE","1i17","PRION-LIKE PROTEIN","Mus musculus",4,"SER A  78;ASP A  77;GLU A  74;GLU A  70","None","1.15A","1knyA-1i17A:undetectable;1knyB-1i17A:0.0","1knyA-1i17A:20.56;1knyB-1i17A:20.56"],["2M9Q_B_BEZB251_0","SERINE PROTEASE INHIBITOR;SERINE PROTEASE SUBUNIT NS2B, SERINE PROTEASE NS3","1i17","PRION-LIKE PROTEIN","Mus musculus",5,"LEU A  88;ILE A  89;ILE A  40;PHE A  71;LEU A  85","None","1.15A","2m9qA-1i17A:undetectable","2m9qA-1i17A:20.44"],["2ZM9_A_ACAA502_1","6-AMINOHEXANOATE-DIMER HYDROLASE","1i17","PRION-LIKE PROTEIN","Mus musculus",4,"ALA A  62;TRP A  86;GLY A   8;ILE A  40","None","0.85A","2zm9A-1i17A:undetectable","2zm9A-1i17A:11.36"]]