SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1i1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		4 / 5 LEU A  36
LEU A  38
SER A 310
GLY A 454
 None
TRP  A1001 (-3.8A)
None
TRP  A1001 ( 3.8A)
 0.68A 1a4lC-1i1qA:
undetectable		 1a4lC-1i1qA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZF_A_TMQA170_1
(DIHYDROFOLATE
REDUCTASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 12 LEU A 373
ALA A 419
LEU A 118
LEU A 411
ALA A 374
 None
 1.11A 1bzfA-1i1qA:
undetectable		 1bzfA-1i1qA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 12 LEU A   8
THR A 199
LEU A 130
LEU A  80
GLY A  77
 None
 1.28A 1d4fA-1i1qA:
undetectable		 1d4fA-1i1qA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 12 LEU A   8
THR A 199
LEU A 130
LEU A  80
GLY A  77
 None
 1.29A 1d4fD-1i1qA:
undetectable		 1d4fD-1i1qA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica) 		4 / 6 LEU B 143
ASP B 159
LEU B  70
HIS B  86
 None
 1.24A 1errB-1i1qB:
0.0		 1errB-1i1qB:
20.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 11 ILE A 326
GLY A 328
THR A 329
GLU A 358
HIS A 398
 None
 1.08A 1i7qA-1i1qA:
54.7		 1i7qA-1i1qA:
71.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I7Q_C_BEZC1502_0
(ANTHRANILATE
SYNTHASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 10 ILE A 326
GLY A 328
THR A 329
GLU A 358
HIS A 398
 None
 1.10A 1i7qC-1i1qA:
54.5		 1i7qC-1i1qA:
71.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		4 / 8 ALA A 213
LEU A 215
ALA A 195
THR A 180
 None
 0.84A 1ie4B-1i1qA:
undetectable
1ie4D-1i1qA:
undetectable		 1ie4B-1i1qA:
13.24
1ie4D-1i1qA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica;
Salmonella
enterica) 		3 / 3 ARG B  21
ARG B  42
ARG A 408
 None
 0.94A 1l7fA-1i1qB:
undetectable		 1l7fA-1i1qB:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica;
Salmonella
enterica) 		3 / 3 ARG B  21
ARG B  42
ARG A 408
 None
 0.93A 1l7hA-1i1qB:
undetectable		 1l7hA-1i1qB:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD205_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica) 		5 / 10 ALA A 160
LEU A 161
GLN A 436
GLU A 260
SER B  11
 None
 1.35A 1wrlC-1i1qA:
undetectable
1wrlD-1i1qA:
0.1		 1wrlC-1i1qA:
10.63
1wrlD-1i1qA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica) 		4 / 5 ALA B 155
PHE B 166
ASN B 146
ASP B 114
 None
 1.13A 1yc2D-1i1qB:
3.3		 1yc2D-1i1qB:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		3 / 3 THR A 199
THR A   7
PRO A   6
 None
 0.79A 209dC-1i1qA:
undetectable		 209dC-1i1qA:
2.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 12 LEU A 208
LEU A 197
GLY A  77
ARG A 207
ALA A  58
 None
 1.15A 2bm9D-1i1qA:
undetectable		 2bm9D-1i1qA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 12 LEU A 208
LEU A 197
GLY A  77
ARG A 207
ALA A  58
 None
 1.09A 2br4A-1i1qA:
undetectable		 2br4A-1i1qA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 12 LEU A 208
LEU A 197
GLY A  77
ARG A 207
ALA A  58
 None
 1.10A 2br4C-1i1qA:
undetectable		 2br4C-1i1qA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 12 LEU A 208
LEU A 197
GLY A  77
ARG A 207
ALA A  58
 None
 1.11A 2br4E-1i1qA:
undetectable		 2br4E-1i1qA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 12 PHE A 304
ILE A 477
ALA A 478
THR A 512
VAL A 506
 None
 1.14A 2g78A-1i1qA:
0.0		 2g78A-1i1qA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 12 ALA A 452
GLY A 450
THR A 464
SER A 311
GLY A 157
 None
 1.02A 2hw2A-1i1qA:
0.0		 2hw2A-1i1qA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 12 HIS A 515
SER A 276
ALA A 279
ALA A 478
GLY A 476
 None
 1.12A 2igtC-1i1qA:
undetectable		 2igtC-1i1qA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica) 		4 / 8 LEU B  16
SER B  54
LEU B   5
ASP B   7
 None
 0.99A 2j2pA-1i1qB:
0.0
2j2pB-1i1qB:
0.0		 2j2pA-1i1qB:
22.37
2j2pB-1i1qB:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		4 / 6 SER A  79
LEU A  80
ASP A  75
GLU A 179
 None
 1.22A 2j2pE-1i1qA:
0.0
2j2pF-1i1qA:
0.0		 2j2pE-1i1qA:
18.90
2j2pF-1i1qA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica;
Salmonella
enterica) 		3 / 3 ARG A 375
ARG B  31
ARG A 117
 None
 1.12A 2jb7A-1i1qA:
1.8
2jb7B-1i1qA:
2.1
2jb7C-1i1qA:
1.9		 2jb7A-1i1qA:
15.31
2jb7B-1i1qA:
15.31
2jb7C-1i1qA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica;
Salmonella
enterica) 		3 / 3 ARG B  31
ARG A 117
ARG A 375
 None
 1.06A 2jb7A-1i1qB:
0.0
2jb7B-1i1qB:
0.0
2jb7C-1i1qB:
0.0		 2jb7A-1i1qB:
23.86
2jb7B-1i1qB:
23.86
2jb7C-1i1qB:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica) 		4 / 5 LEU B 143
ASP B 159
LEU B  70
HIS B  86
 None
 1.24A 2jfaA-1i1qB:
0.0		 2jfaA-1i1qB:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 9 THR A 464
GLY A 454
TYR A 173
LEU A 154
LEU A 312
 None
TRP  A1001 ( 3.8A)
None
None
None
 1.06A 2npnA-1i1qA:
undetectable		 2npnA-1i1qA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica) 		4 / 6 ARG B 130
PHE B 168
ILE B 111
PHE B 119
 None
 1.17A 2qeiA-1i1qB:
undetectable		 2qeiA-1i1qB:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica) 		4 / 5 LEU B 143
ASP B 159
LEU B  70
HIS B  86
 None
 1.24A 2qxsA-1i1qB:
0.0		 2qxsA-1i1qB:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica) 		4 / 5 LEU B 143
ASP B 159
LEU B  70
HIS B  86
 None
 1.25A 2qxsB-1i1qB:
0.0		 2qxsB-1i1qB:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		4 / 7 PHE A 175
ALA A 452
PHE A 127
PHE A 124
 None
 1.07A 2vcvL-1i1qA:
0.0		 2vcvL-1i1qA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		3 / 3 TYR A 173
VAL A 123
THR A  62
 None
 0.73A 2ygnA-1i1qA:
undetectable		 2ygnA-1i1qA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		3 / 3 GLU A 322
ASP A 463
TYR A 292
 None
TRP  A1001 (-4.3A)
TRP  A1001 (-3.9A)
 0.87A 2yvlB-1i1qA:
undetectable		 2yvlB-1i1qA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		3 / 3 THR A   7
PRO A   6
THR A 199
 None
 0.86A 316dC-1i1qA:
undetectable		 316dC-1i1qA:
2.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 12 PHE A 127
ILE A  61
PHE A 301
VAL A 467
THR A 464
 None
 1.38A 3em0B-1i1qA:
2.3		 3em0B-1i1qA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		3 / 3 ARG A 504
VAL A 283
THR A 512
 None
 0.81A 3ndtA-1i1qA:
0.0		 3ndtA-1i1qA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		4 / 6 LEU A 129
LEU A  84
LEU A 177
LEU A  59
 None
 1.00A 3q1eA-1i1qA:
0.0
3q1eC-1i1qA:
0.1		 3q1eA-1i1qA:
11.52
3q1eC-1i1qA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		4 / 6 LEU A 177
LEU A  59
LEU A 129
LEU A  84
 None
 1.08A 3q1eA-1i1qA:
0.0
3q1eC-1i1qA:
0.1		 3q1eA-1i1qA:
11.52
3q1eC-1i1qA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica) 		3 / 3 ARG B  21
THR B  13
TRP B  14
 None
 1.14A 4d7hA-1i1qB:
0.0		 4d7hA-1i1qB:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		4 / 7 ALA A 280
PHE A 304
ALA A 471
PRO A 275
 None
 0.94A 4du2A-1i1qA:
0.0		 4du2A-1i1qA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica) 		4 / 6 GLU B 112
ILE B 111
HIS B  86
VAL B 139
 None
 1.07A 4ejwB-1i1qB:
0.0		 4ejwB-1i1qB:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica) 		3 / 3 LYS B 192
ARG B 162
TRP B 188
 None
 1.46A 4i90A-1i1qB:
0.0		 4i90A-1i1qB:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica) 		4 / 8 LEU B  20
ASN A 115
ASP A 113
ILE B  29
 None
 0.85A 4lzrA-1i1qB:
undetectable		 4lzrA-1i1qB:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 12 PRO A 171
ALA A  63
ARG A 445
ALA A 156
GLY A 157
 None
 1.01A 4oaeA-1i1qA:
undetectable		 4oaeA-1i1qA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica) 		4 / 6 ILE B 145
ARG B 157
GLY B 165
VAL B 163
 None
 1.09A 4oltB-1i1qB:
0.0		 4oltB-1i1qB:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA502_1
(PENTALENIC ACID
SYNTHASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 9 LEU A  52
LEU A 215
THR A 180
LEU A 181
ILE A 193
 None
 1.22A 4ubsA-1i1qA:
0.0		 4ubsA-1i1qA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 12 TYR A 176
GLY A 148
LEU A 130
LEU A  80
ALA A  58
 None
 1.01A 4wcxC-1i1qA:
undetectable		 4wcxC-1i1qA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		3 / 3 LYS A  46
ARG A 332
VAL A 396
 None
 0.81A 4x3uA-1i1qA:
undetectable
4x3uB-1i1qA:
0.0		 4x3uA-1i1qA:
8.75
4x3uB-1i1qA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica) 		5 / 12 LEU B 181
GLY B 178
ILE B  82
GLN B  19
LEU B  16
 None
 1.00A 5b8hA-1i1qB:
2.1
5b8hB-1i1qB:
undetectable		 5b8hA-1i1qB:
23.34
5b8hB-1i1qB:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		3 / 3 VAL A  55
GLN A  27
CYH A  29
 None
 0.82A 5icxA-1i1qA:
0.2
5icxE-1i1qA:
undetectable		 5icxA-1i1qA:
18.24
5icxE-1i1qA:
3.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 12 LEU A 149
GLY A 454
TYR A 455
PHE A 124
LEU A 154
 None
TRP  A1001 ( 3.8A)
None
None
None
 1.38A 5kklB-1i1qA:
0.0		 5kklB-1i1qA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
ANTHRANILATE
SYNTHASE COMPONENT
II
(Salmonella
enterica) 		4 / 7 SER B  11
ASP B  10
PRO B  57
SER A 427
 None
 1.16A 5l1fC-1i1qB:
3.5		 5l1fC-1i1qB:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		5 / 12 LEU A 252
ILE A 261
ALA A 429
ILE A 468
GLY A 450
 None
 1.03A 5veuB-1i1qA:
0.0		 5veuB-1i1qA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 1i1q ANTHRANILATE
SYNTHASE COMPONENT I
(Salmonella
enterica) 		3 / 3 VAL A 404
ALA A 385
GLN A 320
 None
 0.65A 6gb9A-1i1qA:
0.0		 6gb9A-1i1qA:
23.62