SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1i31'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		3 / 3 GLU A 172
TYR A 205
PHE A 174
 None
 0.78A 1eqbB-1i31A:
undetectable		 1eqbB-1i31A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		3 / 3 GLU A 172
TYR A 205
PHE A 174
 None
 0.77A 1eqbA-1i31A:
undetectable		 1eqbA-1i31A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		3 / 3 GLU A 172
TYR A 205
PHE A 174
 None
 0.77A 1eqbD-1i31A:
undetectable		 1eqbD-1i31A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		3 / 3 GLU A 172
TYR A 205
PHE A 174
 None
 0.77A 1eqbC-1i31A:
undetectable		 1eqbC-1i31A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 9 CYH A 435
LEU A 301
ILE A 351
THR A 433
ILE A 386
 None
 1.38A 1hzeA-1i31A:
0.0
1hzeB-1i31A:
undetectable		 1hzeA-1i31A:
12.94
1hzeB-1i31A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 9 THR A 433
ILE A 386
CYH A 435
LEU A 301
ILE A 351
 None
 1.38A 1hzeA-1i31A:
0.0
1hzeB-1i31A:
undetectable		 1hzeA-1i31A:
12.94
1hzeB-1i31A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 10 THR A 433
ILE A 386
CYH A 435
LEU A 301
ILE A 351
 None
 1.39A 1i18A-1i31A:
0.0
1i18B-1i31A:
0.0		 1i18A-1i31A:
12.94
1i18B-1i31A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_B_SALB258_1
(TRANSCRIPTIONAL
REGULATOR)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 11 ALA A 317
LEU A 316
PHE A 394
GLY A 360
SER A 309
 None
 1.14A 3bpxA-1i31A:
undetectable
3bpxB-1i31A:
undetectable		 3bpxA-1i31A:
19.55
3bpxB-1i31A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EQM_A_ASDA601_1
(CYTOCHROME P450 19A1)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 10 ILE A 263
PHE A 265
VAL A 401
MET A 202
LEU A 404
 None
 1.27A 3eqmA-1i31A:
0.0		 3eqmA-1i31A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		6 / 11 ARG A 323
GLN A 318
VAL A 392
PRO A 393
PRO A 286
ILE A 307
 None
 1.31A 3ganA-1i31A:
undetectable		 3ganA-1i31A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		3 / 3 GLY A 332
PRO A 327
LEU A 372
 None
 0.54A 3hcpB-1i31A:
undetectable		 3hcpB-1i31A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		4 / 8 ILE A 366
ALA A 350
THR A 326
VAL A 335
 None
 0.90A 3me6B-1i31A:
0.0		 3me6B-1i31A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 12 ILE A 263
PHE A 265
VAL A 401
MET A 202
LEU A 404
 None
 1.28A 3s79A-1i31A:
0.0		 3s79A-1i31A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		3 / 3 LYS A 312
PRO A 313
SER A 314
 None
 0.40A 4k50I-1i31A:
0.0		 4k50I-1i31A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		4 / 6 ILE A 307
GLY A 189
MET A 185
ILE A 290
 None
 0.95A 5j4nB-1i31A:
undetectable		 5j4nB-1i31A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 11 ILE A 263
PHE A 265
VAL A 401
MET A 202
LEU A 404
 None
 1.20A 5jkwA-1i31A:
0.0		 5jkwA-1i31A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL7_A_ASDA601_1
(AROMATASE)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 10 ILE A 263
PHE A 265
VAL A 401
MET A 202
LEU A 404
 None
 1.21A 5jl7A-1i31A:
0.0		 5jl7A-1i31A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		4 / 6 ASN A 182
PRO A 396
VAL A 196
TYR A 431
 None
 1.10A 5umd2-1i31A:
0.0
5umdF-1i31A:
0.0		 5umd2-1i31A:
13.22
5umdF-1i31A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		3 / 3 ARG A 162
PHE A 407
LEU A 206
 None
 0.39A 5x1bC-1i31A:
undetectable		 5x1bC-1i31A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		4 / 7 VAL A 177
VAL A 196
PRO A 396
GLY A 398
 None
 0.98A 5x80C-1i31A:
undetectable
5x80D-1i31A:
undetectable		 5x80C-1i31A:
19.39
5x80D-1i31A:
19.39