SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1i3g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7A_B_PFLB4002_1 (SERUM ALBUMIN)	1i3g	ANTIBODY FV FRAGMENT (Mus musculus)	4 / 6	LEU L 145 VAL L 19 VAL L 15 GLN L 97	None	1.05A	1e7aB-1i3gL: undetectable	1e7aB-1i3gL: 10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FBM_B_RTLB951_0 (PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN))	1i3g	ANTIBODY FV FRAGMENT (Mus musculus)	4 / 4	THR H 97 LEU H 96 LEU H 21 GLN H 6	None	1.22A	1fbmA-1i3gH: undetectable	1fbmA-1i3gH: 13.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1H8S_A_AICA1000_1 (MUTANT AL2 6E7P9G)	1i3g	ANTIBODY FV FRAGMENT (Mus musculus)	11 / 12	TYR L 44 GLN L 107 TYR L 135 LEU L 137 PHE L 139 TRP H 40 ASN H 42 VAL H 44 ASN H 57 ALA H 107 TRP H 139	None MPD L 500 (-3.1A) None None None None MPD L 500 (-3.8A) None None MPD L 500 ( 3.9A) MPD L 500 (-4.5A)	0.33A	1h8sA-1i3gL: 23.3	1h8sA-1i3gL: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HGX_A_SALA102_1 (SALICYLATE BIOSYNTHESIS PROTEIN PCHB)	1i3g	ANTIBODY FV FRAGMENT (Mus musculus)	4 / 7	ARG H 108 VAL H 2 TYR H 29 GLN H 1	None	1.05A	3hgxA-1i3gH: undetectable	3hgxA-1i3gH: 17.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LS4_H_TCIH220_2 (HEAVY CHAIN OF ANTIBODY FAB FRAGMENT LIGHT CHAIN OF ANTIBODY FAB FRAGMENT)	1i3g	ANTIBODY FV FRAGMENT (Mus musculus)	4 / 5	TYR L 44 GLN L 107 LEU L 137 PHE L 139	None MPD L 500 (-3.1A) None None	0.52A	3ls4L-1i3gL: 21.4	3ls4L-1i3gL: 59.82

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E7A_B_PFLB4002_1","SERUM ALBUMIN","1i3g","ANTIBODY FV FRAGMENT","Mus musculus",4,"LEU L 145;VAL L  19;VAL L  15;GLN L  97","None","1.05A","1e7aB-1i3gL:undetectable","1e7aB-1i3gL:10.43"],["1FBM_B_RTLB951_0","PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN)","1i3g","ANTIBODY FV FRAGMENT","Mus musculus",4,"THR H  97;LEU H  96;LEU H  21;GLN H   6","None","1.22A","1fbmA-1i3gH:undetectable","1fbmA-1i3gH:13.91"],["1H8S_A_AICA1000_1","MUTANT AL2 6E7P9G","1i3g","ANTIBODY FV FRAGMENT","Mus musculus",11,"TYR L  44;GLN L 107;TYR L 135;LEU L 137;PHE L 139;TRP H  40;ASN H  42;VAL H  44;ASN H  57;ALA H 107;TRP H 139","None;MPD L 500 (-3.1A);None;None;None;None;MPD L 500 (-3.8A);None;None;MPD L 500 ( 3.9A);MPD L 500 (-4.5A)","0.33A","1h8sA-1i3gL:23.3","1h8sA-1i3gL:100.00"],["3HGX_A_SALA102_1","SALICYLATE BIOSYNTHESIS PROTEIN PCHB","1i3g","ANTIBODY FV FRAGMENT","Mus musculus",4,"ARG H 108;VAL H   2;TYR H  29;GLN H   1","None","1.05A","3hgxA-1i3gH:undetectable","3hgxA-1i3gH:17.39"],["3LS4_H_TCIH220_2","HEAVY CHAIN OF ANTIBODY FAB FRAGMENT;LIGHT CHAIN OF ANTIBODY FAB FRAGMENT","1i3g","ANTIBODY FV FRAGMENT","Mus musculus",4,"TYR L  44;GLN L 107;LEU L 137;PHE L 139","None;MPD L 500 (-3.1A);None;None","0.52A","3ls4L-1i3gL:21.4","3ls4L-1i3gL:59.82"]]