SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1i60'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 1i60 IOLI PROTEIN
(Bacillus
subtilis) 		5 / 12 LEU A 171
GLY A 170
VAL A 104
ALA A  64
LEU A  63
 None
 1.01A 1gs4A-1i60A:
undetectable		 1gs4A-1i60A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 1i60 IOLI PROTEIN
(Bacillus
subtilis) 		4 / 6 ASN A  66
LEU A  16
LEU A  11
ILE A  31
 None
 0.93A 1z95A-1i60A:
0.0		 1z95A-1i60A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 1i60 IOLI PROTEIN
(Bacillus
subtilis) 		3 / 3 VAL A 151
VAL A 104
ASP A  75
 None
 0.74A 2fumD-1i60A:
undetectable		 2fumD-1i60A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 1i60 IOLI PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A  78
ASP A 123
ILE A 139
LEU A 141
ASN A  73
 None
 1.12A 3eeoA-1i60A:
2.3		 3eeoA-1i60A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 1i60 IOLI PROTEIN
(Bacillus
subtilis) 		3 / 3 GLU A  32
VAL A 245
CYH A   4
 None
 0.98A 3fbxA-1i60A:
0.0		 3fbxA-1i60A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 1i60 IOLI PROTEIN
(Bacillus
subtilis) 		5 / 12 ILE A 201
VAL A 243
ILE A 196
VAL A 271
ARG A 217
 None
 1.25A 3fpjB-1i60A:
undetectable		 3fpjB-1i60A:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 1i60 IOLI PROTEIN
(Bacillus
subtilis) 		3 / 3 PHE A 143
TYR A 158
LEU A 106
 None
 0.62A 3keeB-1i60A:
0.0		 3keeB-1i60A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 1i60 IOLI PROTEIN
(Bacillus
subtilis) 		4 / 5 ASN A  15
ASP A  37
GLU A  85
SER A  14
 None
 1.08A 3p2kC-1i60A:
undetectable		 3p2kC-1i60A:
25.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1i60 IOLI PROTEIN
(Bacillus
subtilis) 		3 / 3 PHE A 143
TYR A 158
LEU A 106
 None
 0.77A 3sueB-1i60A:
undetectable		 3sueB-1i60A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 1i60 IOLI PROTEIN
(Bacillus
subtilis) 		5 / 12 ILE A 198
SER A 244
TYR A 199
PHE A 239
LEU A 234
 None
 0.99A 3vw1B-1i60A:
undetectable		 3vw1B-1i60A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 1i60 IOLI PROTEIN
(Bacillus
subtilis) 		4 / 7 ASN A  66
LEU A  16
LEU A  11
ILE A  31
 None
 0.89A 4okwA-1i60A:
0.0		 4okwA-1i60A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 1i60 IOLI PROTEIN
(Bacillus
subtilis) 		4 / 6 SER A  47
LEU A  48
ASP A  49
LEU A  43
 None
 0.85A 4wozA-1i60A:
6.9
4wozB-1i60A:
6.4		 4wozA-1i60A:
23.60
4wozB-1i60A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 1i60 IOLI PROTEIN
(Bacillus
subtilis) 		4 / 6 ASP A  49
PRO A  40
TYR A  42
LEU A  16
 None
 1.36A 5bmvB-1i60A:
undetectable		 5bmvB-1i60A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 1i60 IOLI PROTEIN
(Bacillus
subtilis) 		3 / 3 ALA A 233
VAL A 272
TYR A 275
 None
 0.69A 5zmqH-1i60A:
undetectable		 5zmqH-1i60A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1i60 IOLI PROTEIN
(Bacillus
subtilis) 		4 / 6 ILE A 139
LEU A 128
MET A  90
THR A  92
 None
 1.11A 6nmfN-1i60A:
undetectable
6nmfW-1i60A:
undetectable		 6nmfN-1i60A:
18.79
6nmfW-1i60A:
14.14