SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1i7f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9P_A_DESA459_1 (ESTROGEN-RELATED RECEPTOR GAMMA)	1i7f	HEAT SHOCK PROTEIN 33 (Escherichia coli)	5 / 12	LEU A 47 LEU A 50 ALA A 53 LEU A 57 ILE A 33	None	1.08A	1s9pA-1i7fA: undetectable	1s9pA-1i7fA: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CEO_A_T44A1395_1 (THYROXINE-BINDING GLOBULIN)	1i7f	HEAT SHOCK PROTEIN 33 (Escherichia coli)	5 / 11	ALA A 94 LEU A 30 LEU A 47 ASN A 45 LEU A 34	None	1.11A	2ceoA-1i7fA: 0.0	2ceoA-1i7fA: 21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FIA_A_0U9A601_1 (CHOLESTEROL 24-HYDROXYLASE)	1i7f	HEAT SHOCK PROTEIN 33 (Escherichia coli)	5 / 12	TYR A 145 LEU A 142 VAL A 115 ALA A 53 THR A 54	None	1.22A	4fiaA-1i7fA: 0.0	4fiaA-1i7fA: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FIA_A_198A602_1 (CHOLESTEROL 24-HYDROXYLASE)	1i7f	HEAT SHOCK PROTEIN 33 (Escherichia coli)	5 / 12	TYR A 145 LEU A 142 VAL A 115 ALA A 53 THR A 54	None	1.22A	4fiaA-1i7fA: 0.0	4fiaA-1i7fA: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UTU_H_ADNH503_2 (ADENOSYLHOMOCYSTEINA SE)	1i7f	HEAT SHOCK PROTEIN 33 (Escherichia coli)	4 / 5	THR A 137 GLU A 143 THR A 154 LEU A 57	None	1.23A	5utuH-1i7fA: undetectable	5utuH-1i7fA: 20.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1S9P_A_DESA459_1","ESTROGEN-RELATED RECEPTOR GAMMA","1i7f","HEAT SHOCK PROTEIN 33","Escherichia coli",5,"LEU A  47;LEU A  50;ALA A  53;LEU A  57;ILE A  33","None","1.08A","1s9pA-1i7fA:undetectable","1s9pA-1i7fA:25.00"],["2CEO_A_T44A1395_1","THYROXINE-BINDING GLOBULIN","1i7f","HEAT SHOCK PROTEIN 33","Escherichia coli",5,"ALA A  94;LEU A  30;LEU A  47;ASN A  45;LEU A  34","None","1.11A","2ceoA-1i7fA:0.0","2ceoA-1i7fA:21.77"],["4FIA_A_0U9A601_1","CHOLESTEROL 24-HYDROXYLASE","1i7f","HEAT SHOCK PROTEIN 33","Escherichia coli",5,"TYR A 145;LEU A 142;VAL A 115;ALA A  53;THR A  54","None","1.22A","4fiaA-1i7fA:0.0","4fiaA-1i7fA:20.74"],["4FIA_A_198A602_1","CHOLESTEROL 24-HYDROXYLASE","1i7f","HEAT SHOCK PROTEIN 33","Escherichia coli",5,"TYR A 145;LEU A 142;VAL A 115;ALA A  53;THR A  54","None","1.22A","4fiaA-1i7fA:0.0","4fiaA-1i7fA:20.74"],["5UTU_H_ADNH503_2","ADENOSYLHOMOCYSTEINASE","1i7f","HEAT SHOCK PROTEIN 33","Escherichia coli",4,"THR A 137;GLU A 143;THR A 154;LEU A  57","None","1.23A","5utuH-1i7fA:undetectable","5utuH-1i7fA:20.52"]]