SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1i7h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1i7h FERREDOXIN
(Escherichia
coli) 		3 / 3 SER A  83
GLU A  82
GLU A  80
 None
 0.62A 1eqbD-1i7hA:
undetectable		 1eqbD-1i7hA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1i7h FERREDOXIN
(Escherichia
coli) 		3 / 3 SER A  83
GLU A  82
GLU A  80
 None
 0.62A 1eqbB-1i7hA:
undetectable		 1eqbB-1i7hA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_1
(HIV-1 PROTEASE)		 1i7h FERREDOXIN
(Escherichia
coli) 		6 / 12 ALA A  30
ASP A  29
ILE A  38
GLY A  35
VAL A   5
ILE A   4
 None
 1.31A 3d1yA-1i7hA:
undetectable		 3d1yA-1i7hA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 1i7h FERREDOXIN
(Escherichia
coli) 		6 / 12 ALA A  30
ASP A  29
ILE A  38
GLY A  35
VAL A   5
ILE A   4
 None
 1.29A 5kqxA-1i7hA:
undetectable		 5kqxA-1i7hA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1i7h FERREDOXIN
(Escherichia
coli) 		5 / 10 TYR A 103
ILE A  54
HIS A 107
ILE A 105
ASN A 106
 None
 1.24A 5vkqA-1i7hA:
undetectable
5vkqD-1i7hA:
undetectable		 5vkqA-1i7hA:
5.51
5vkqD-1i7hA:
5.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1i7h FERREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 107
ILE A 105
ASN A 106
TYR A 103
ILE A  54
 None
 1.21A 5vkqA-1i7hA:
undetectable
5vkqB-1i7hA:
undetectable		 5vkqA-1i7hA:
5.51
5vkqB-1i7hA:
5.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1i7h FERREDOXIN
(Escherichia
coli) 		4 / 8 SER A  65
PHE A  59
HIS A  52
ILE A  54
 None
 0.94A 5vkqB-1i7hA:
undetectable
5vkqC-1i7hA:
undetectable		 5vkqB-1i7hA:
5.51
5vkqC-1i7hA:
5.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1i7h FERREDOXIN
(Escherichia
coli) 		5 / 10 HIS A 107
ILE A 105
ASN A 106
TYR A 103
ILE A  54
 None
 1.22A 5vkqC-1i7hA:
undetectable
5vkqD-1i7hA:
undetectable		 5vkqC-1i7hA:
5.51
5vkqD-1i7hA:
5.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 1i7h FERREDOXIN
(Escherichia
coli) 		4 / 6 GLU A  39
ARG A 109
GLU A 110
ALA A 108
 None
 0.99A 6an0A-1i7hA:
undetectable		 6an0A-1i7hA:
14.42