SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1i7o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CBR_A_REAA200_1 (CELLULAR RETINOIC ACID BINDING PROTEIN TYPE I)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	LEU A 68 ALA A 67 ALA A 92 PRO A 117 THR A 44	None	1.24A	1cbrA-1i7oA: undetectable	1cbrA-1i7oA: 16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CBR_A_REAA200_1 (CELLULAR RETINOIC ACID BINDING PROTEIN TYPE I)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	LEU A 251 ALA A 227 ALA A 392 THR A 303 LEU A 418	None	1.23A	1cbrA-1i7oA: undetectable	1cbrA-1i7oA: 16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CBR_B_REAB200_1 (CELLULAR RETINOIC ACID BINDING PROTEIN TYPE I)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	LEU A 68 ALA A 67 ALA A 92 PRO A 117 THR A 44	None	1.24A	1cbrB-1i7oA: undetectable	1cbrB-1i7oA: 16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CBR_B_REAB200_1 (CELLULAR RETINOIC ACID BINDING PROTEIN TYPE I)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	LEU A 251 ALA A 227 ALA A 392 THR A 303 LEU A 418	None	1.23A	1cbrB-1i7oA: undetectable	1cbrB-1i7oA: 16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_C_ACTC3004_0 (BETA-CARBONIC ANHYDRASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	4 / 6	CYH A 305 ASP A 307 VAL A 280 GLY A 394	None CA A1001 (-3.3A) None CA A1001 ( 4.7A)	1.18A	1ekjC-1i7oA: undetectable 1ekjD-1i7oA: undetectable	1ekjC-1i7oA: 19.68 1ekjD-1i7oA: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_C_ACTC3007_0 (BETA-CARBONIC ANHYDRASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	4 / 6	CYH A 305 ASP A 307 VAL A 280 GLY A 394	None CA A1001 (-3.3A) None CA A1001 ( 4.7A)	1.17A	1ekjC-1i7oA: undetectable 1ekjD-1i7oA: undetectable	1ekjC-1i7oA: 19.68 1ekjD-1i7oA: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HBP_A_RTLA184_0 (RETINOL BINDING PROTEIN)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 11	LEU A 279 ALA A 293 ALA A 295 VAL A 281 MET A 296	None	1.24A	1hbpA-1i7oA: 0.0	1hbpA-1i7oA: 16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OLT_A_SAMA501_0 (OXYGEN-INDEPENDENT COPROPORPHYRINOGEN III OXIDASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	GLY A 169 ASP A 170 ILE A 172 PHE A 6 ALA A 159	None	1.21A	1oltA-1i7oA: undetectable	1oltA-1i7oA: 24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T87_B_CAMB2422_0 (CYTOCHROME P450-CAM)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	4 / 7	THR A 393 LEU A 368 VAL A 299 ILE A 376	None	0.90A	1t87B-1i7oA: undetectable	1t87B-1i7oA: 21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLS_B_C2FB266_0 (THYMIDYLATE SYNTHASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	SER A 96 LEU A 16 GLY A 175 VAL A 36 ALA A 35	None	1.15A	1tlsB-1i7oA: 0.0	1tlsB-1i7oA: 18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1U18_B_HSMB402_1 (NITROPHORIN 1)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	4 / 5	GLU A 411 THR A 364 LEU A 349 LEU A 351	None	1.17A	1u18B-1i7oA: 0.0	1u18B-1i7oA: 17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z9H_A_IMNA379_1 (MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	PRO A 168 PRO A 254 VAL A 77 SER A 161 VAL A 70	None	1.41A	1z9hA-1i7oA: 0.0	1z9hA-1i7oA: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z9H_B_IMNB381_1 (MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	PRO A 168 PRO A 254 VAL A 77 SER A 161 VAL A 70	None	1.42A	1z9hB-1i7oA: 0.0	1z9hB-1i7oA: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z9H_C_IMNC379_1 (MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	PRO A 168 PRO A 254 VAL A 77 SER A 161 VAL A 70	None	1.42A	1z9hC-1i7oA: 0.0	1z9hC-1i7oA: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BM9_A_SAMA301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	LEU A 157 LEU A 166 GLY A 71 ALA A 87 ALA A 123	None	1.13A	2bm9A-1i7oA: undetectable	2bm9A-1i7oA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q8H_A_TF4A438_1 ([PYRUVATE DEHYDROGENASE [LIPOAMIDE]] KINASE ISOZYME 1)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	4 / 6	LEU A 330 TYR A 308 ILE A 310 ARG A 266	None	0.97A	2q8hA-1i7oA: undetectable	2q8hA-1i7oA: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YS6_A_GLYA431_0 (PHOSPHORIBOSYLGLYCIN AMIDE SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	4 / 8	ASP A 307 LYS A 325 GLY A 394 GLU A 278	CA A1001 (-3.3A) CA A1001 ( 4.0A) CA A1001 ( 4.7A) CA A1001 (-2.8A)	0.88A	2ys6A-1i7oA: undetectable	2ys6A-1i7oA: 22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FHJ_A_TRPA1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 10	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.27A	3fhjA-1i7oA: undetectable	3fhjA-1i7oA: 23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FHJ_B_TRPB1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 10	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.27A	3fhjB-1i7oA: undetectable	3fhjB-1i7oA: 23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FHJ_C_TRPC1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 10	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.27A	3fhjC-1i7oA: undetectable	3fhjC-1i7oA: 23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FHJ_D_TRPD1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 9	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.27A	3fhjD-1i7oA: undetectable	3fhjD-1i7oA: 23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FHJ_E_TRPE1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 10	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.28A	3fhjE-1i7oA: undetectable	3fhjE-1i7oA: 23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FHJ_F_TRPF1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 9	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.28A	3fhjF-1i7oA: undetectable	3fhjF-1i7oA: 23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_A_TRPA1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 9	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.30A	3fi0A-1i7oA: undetectable	3fi0A-1i7oA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_B_TRPB1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 8	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.29A	3fi0B-1i7oA: undetectable	3fi0B-1i7oA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_C_TRPC1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 9	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.28A	3fi0C-1i7oA: undetectable	3fi0C-1i7oA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_D_TRPD1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 9	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.31A	3fi0D-1i7oA: undetectable	3fi0D-1i7oA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_F_TRPF1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 9	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.29A	3fi0F-1i7oA: 0.0	3fi0F-1i7oA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_G_TRPG1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 8	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.25A	3fi0G-1i7oA: undetectable	3fi0G-1i7oA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_H_TRPH1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 9	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.27A	3fi0H-1i7oA: undetectable	3fi0H-1i7oA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_I_TRPI1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 8	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.27A	3fi0I-1i7oA: undetectable	3fi0I-1i7oA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_J_TRPJ1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 9	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.29A	3fi0J-1i7oA: 0.0	3fi0J-1i7oA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_K_TRPK1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 9	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.31A	3fi0K-1i7oA: undetectable	3fi0K-1i7oA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_L_TRPL1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 9	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.29A	3fi0L-1i7oA: undetectable	3fi0L-1i7oA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_M_TRPM1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 9	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.27A	3fi0M-1i7oA: undetectable	3fi0M-1i7oA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_N_TRPN1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 9	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.30A	3fi0N-1i7oA: undetectable	3fi0N-1i7oA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_O_TRPO1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 9	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.27A	3fi0O-1i7oA: undetectable	3fi0O-1i7oA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_Q_TRPQ1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 8	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.27A	3fi0Q-1i7oA: undetectable	3fi0Q-1i7oA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_R_TRPR1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 9	VAL A 372 HIS A 347 ILE A 343 VAL A 415 VAL A 412	None	1.28A	3fi0R-1i7oA: undetectable	3fi0R-1i7oA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OKX_A_SAMA201_0 (YAEB-LIKE PROTEIN RPA0152)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	LEU A 375 TYR A 232 LEU A 368 THR A 364 LEU A 228	None	1.32A	3okxA-1i7oA: 0.0	3okxA-1i7oA: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OKX_B_SAMB201_1 (YAEB-LIKE PROTEIN RPA0152)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	LEU A 375 TYR A 232 LEU A 368 THR A 364 LEU A 228	None	1.32A	3okxB-1i7oA: 0.0	3okxB-1i7oA: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SPK_A_TPVA100_2 (HIV-1 PROTEASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	4 / 7	ALA A 153 GLY A 88 ILE A 69 THR A 65	None	0.87A	3spkB-1i7oA: undetectable	3spkB-1i7oA: 15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUF_B_SUEB1201_2 (NS3 PROTEASE, NS4A PROTEIN)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	3 / 3	TYR A 313 LEU A 230 ARG A 311	None	0.72A	3sufB-1i7oA: 0.0	3sufB-1i7oA: 18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DF3_A_SAMA301_0 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	ALA A 287 ALA A 295 VAL A 290 ALA A 300 ASP A 389	None	1.28A	4df3A-1i7oA: undetectable	4df3A-1i7oA: 23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DF3_B_SAMB301_0 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	ALA A 287 ALA A 295 VAL A 290 ALA A 300 ASP A 389	None	1.23A	4df3B-1i7oA: undetectable	4df3B-1i7oA: 23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FIA_A_0U9A601_1 (CHOLESTEROL 24-HYDROXYLASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	TYR A 378 LEU A 379 PHE A 226 VAL A 249 ARG A 288	None	1.26A	4fiaA-1i7oA: 0.0	4fiaA-1i7oA: 24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FIA_A_198A602_1 (CHOLESTEROL 24-HYDROXYLASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	TYR A 378 LEU A 379 PHE A 226 VAL A 249 ARG A 288	None	1.26A	4fiaA-1i7oA: 0.0	4fiaA-1i7oA: 24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O2B_B_LOCB503_1 (TUBULIN ALPHA-1B CHAIN TUBULIN BETA-2B CHAIN)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	3 / 3	SER A 125 ALA A 123 VAL A 122	None	0.60A	4o2bA-1i7oA: undetectable	4o2bA-1i7oA: 20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OQR_A_2UOA502_1 (CYP105AS1)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 9	ILE A 69 ALA A 67 THR A 65 VAL A 191 ALA A 193	None	1.08A	4oqrA-1i7oA: 0.0	4oqrA-1i7oA: 22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QD3_A_5AEA201_1 (PEPTIDYL-TRNA HYDROLASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 9	GLY A 114 VAL A 95 SER A 96 VAL A 60 LEU A 97	None	1.22A	4qd3A-1i7oA: undetectable	4qd3A-1i7oA: 19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QRC_A_0LIA802_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	4 / 8	VAL A 77 ILE A 86 ALA A 153 LEU A 68	None	0.80A	4qrcA-1i7oA: undetectable	4qrcA-1i7oA: 23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UDA_A_DEXA1985_2 (MINERALOCORTICOID RECEPTOR)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	4 / 6	LEU A 225 LEU A 322 PHE A 6 THR A 4	None	1.11A	4udaA-1i7oA: undetectable	4udaA-1i7oA: 21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSD_B_1GNB603_1 (PHIAB6 TAILSPIKE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	3 / 3	VAL A 249 GLU A 276 GLU A 278	None CA A1001 (-3.1A) CA A1001 (-2.8A)	0.48A	5jsdB-1i7oA: 0.0 5jsdC-1i7oA: 0.0	5jsdB-1i7oA: 18.60 5jsdC-1i7oA: 18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5U4S_A_BEZA301_0 (PUTATIVE SHORT CHAIN DEHYDROGENASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	4 / 7	ASN A 43 ILE A 283 LEU A 385 MET A 383	None	0.99A	5u4sA-1i7oA: undetectable	5u4sA-1i7oA: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5U4S_B_BEZB301_0 (PUTATIVE SHORT CHAIN DEHYDROGENASE)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	4 / 8	ASN A 43 ILE A 283 LEU A 385 MET A 383	None	1.00A	5u4sB-1i7oA: undetectable	5u4sB-1i7oA: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA312_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	3 / 3	ILE A 107 VAL A 249 PRO A 247	None	0.70A	5uunA-1i7oA: undetectable	5uunA-1i7oA: 22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_A_CVIA301_0 (REGULATORY PROTEIN TETR)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	5 / 12	ALA A 377 SER A 380 LEU A 385 ILE A 283 TYR A 302	None	1.46A	5vlmA-1i7oA: undetectable	5vlmA-1i7oA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5V_B_ECLB1001_1 (TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5)	1i7o	4-HYDROXYPHENYLACETA TE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYL ASE (Escherichia coli)	4 / 7	ALA A 253 PHE A 163 LEU A 160 ILE A 118	None	0.80A	6b5vA-1i7oA: undetectable 6b5vB-1i7oA: undetectable	6b5vA-1i7oA: 12.47 6b5vB-1i7oA: 12.47

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1CBR_A_REAA200_1","CELLULAR RETINOIC ACID BINDING PROTEIN TYPE I","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"LEU A  68;ALA A  67;ALA A  92;PRO A 117;THR A  44","None","1.24A","1cbrA-1i7oA:undetectable","1cbrA-1i7oA:16.90"],["1CBR_A_REAA200_1","CELLULAR RETINOIC ACID BINDING PROTEIN TYPE I","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"LEU A 251;ALA A 227;ALA A 392;THR A 303;LEU A 418","None","1.23A","1cbrA-1i7oA:undetectable","1cbrA-1i7oA:16.90"],["1CBR_B_REAB200_1","CELLULAR RETINOIC ACID BINDING PROTEIN TYPE I","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"LEU A  68;ALA A  67;ALA A  92;PRO A 117;THR A  44","None","1.24A","1cbrB-1i7oA:undetectable","1cbrB-1i7oA:16.90"],["1CBR_B_REAB200_1","CELLULAR RETINOIC ACID BINDING PROTEIN TYPE I","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"LEU A 251;ALA A 227;ALA A 392;THR A 303;LEU A 418","None","1.23A","1cbrB-1i7oA:undetectable","1cbrB-1i7oA:16.90"],["1EKJ_C_ACTC3004_0","BETA-CARBONIC ANHYDRASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",4,"CYH A 305;ASP A 307;VAL A 280;GLY A 394","None; CA A1001 (-3.3A);None; CA A1001 ( 4.7A)","1.18A","1ekjC-1i7oA:undetectable;1ekjD-1i7oA:undetectable","1ekjC-1i7oA:19.68;1ekjD-1i7oA:19.68"],["1EKJ_C_ACTC3007_0","BETA-CARBONIC ANHYDRASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",4,"CYH A 305;ASP A 307;VAL A 280;GLY A 394","None; CA A1001 (-3.3A);None; CA A1001 ( 4.7A)","1.17A","1ekjC-1i7oA:undetectable;1ekjD-1i7oA:undetectable","1ekjC-1i7oA:19.68;1ekjD-1i7oA:19.68"],["1HBP_A_RTLA184_0","RETINOL BINDING PROTEIN","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"LEU A 279;ALA A 293;ALA A 295;VAL A 281;MET A 296","None","1.24A","1hbpA-1i7oA:0.0","1hbpA-1i7oA:16.78"],["1OLT_A_SAMA501_0","OXYGEN-INDEPENDENT COPROPORPHYRINOGEN III OXIDASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"GLY A 169;ASP A 170;ILE A 172;PHE A   6;ALA A 159","None","1.21A","1oltA-1i7oA:undetectable","1oltA-1i7oA:24.41"],["1T87_B_CAMB2422_0","CYTOCHROME P450-CAM","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",4,"THR A 393;LEU A 368;VAL A 299;ILE A 376","None","0.90A","1t87B-1i7oA:undetectable","1t87B-1i7oA:21.92"],["1TLS_B_C2FB266_0","THYMIDYLATE SYNTHASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"SER A  96;LEU A  16;GLY A 175;VAL A  36;ALA A  35","None","1.15A","1tlsB-1i7oA:0.0","1tlsB-1i7oA:18.84"],["1U18_B_HSMB402_1","NITROPHORIN 1","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",4,"GLU A 411;THR A 364;LEU A 349;LEU A 351","None","1.17A","1u18B-1i7oA:0.0","1u18B-1i7oA:17.91"],["1Z9H_A_IMNA379_1","MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"PRO A 168;PRO A 254;VAL A  77;SER A 161;VAL A  70","None","1.41A","1z9hA-1i7oA:0.0","1z9hA-1i7oA:20.40"],["1Z9H_B_IMNB381_1","MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"PRO A 168;PRO A 254;VAL A  77;SER A 161;VAL A  70","None","1.42A","1z9hB-1i7oA:0.0","1z9hB-1i7oA:20.40"],["1Z9H_C_IMNC379_1","MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"PRO A 168;PRO A 254;VAL A  77;SER A 161;VAL A  70","None","1.42A","1z9hC-1i7oA:0.0","1z9hC-1i7oA:20.40"],["2BM9_A_SAMA301_0","CEPHALOSPORIN HYDROXYLASE CMCI","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"LEU A 157;LEU A 166;GLY A  71;ALA A  87;ALA A 123","None","1.13A","2bm9A-1i7oA:undetectable","2bm9A-1i7oA:18.33"],["2Q8H_A_TF4A438_1","[PYRUVATE DEHYDROGENASE [LIPOAMIDE]] KINASE ISOZYME 1","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",4,"LEU A 330;TYR A 308;ILE A 310;ARG A 266","None","0.97A","2q8hA-1i7oA:undetectable","2q8hA-1i7oA:21.96"],["2YS6_A_GLYA431_0","PHOSPHORIBOSYLGLYCINAMIDE SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",4,"ASP A 307;LYS A 325;GLY A 394;GLU A 278"," CA A1001 (-3.3A); CA A1001 ( 4.0A); CA A1001 ( 4.7A); CA A1001 (-2.8A)","0.88A","2ys6A-1i7oA:undetectable","2ys6A-1i7oA:22.41"],["3FHJ_A_TRPA1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.27A","3fhjA-1i7oA:undetectable","3fhjA-1i7oA:23.49"],["3FHJ_B_TRPB1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.27A","3fhjB-1i7oA:undetectable","3fhjB-1i7oA:23.49"],["3FHJ_C_TRPC1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.27A","3fhjC-1i7oA:undetectable","3fhjC-1i7oA:23.49"],["3FHJ_D_TRPD1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.27A","3fhjD-1i7oA:undetectable","3fhjD-1i7oA:23.49"],["3FHJ_E_TRPE1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.28A","3fhjE-1i7oA:undetectable","3fhjE-1i7oA:23.49"],["3FHJ_F_TRPF1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.28A","3fhjF-1i7oA:undetectable","3fhjF-1i7oA:23.49"],["3FI0_A_TRPA1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.30A","3fi0A-1i7oA:undetectable","3fi0A-1i7oA:24.78"],["3FI0_B_TRPB1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.29A","3fi0B-1i7oA:undetectable","3fi0B-1i7oA:24.78"],["3FI0_C_TRPC1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.28A","3fi0C-1i7oA:undetectable","3fi0C-1i7oA:24.78"],["3FI0_D_TRPD1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.31A","3fi0D-1i7oA:undetectable","3fi0D-1i7oA:24.78"],["3FI0_F_TRPF1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.29A","3fi0F-1i7oA:0.0","3fi0F-1i7oA:24.78"],["3FI0_G_TRPG1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.25A","3fi0G-1i7oA:undetectable","3fi0G-1i7oA:24.78"],["3FI0_H_TRPH1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.27A","3fi0H-1i7oA:undetectable","3fi0H-1i7oA:24.78"],["3FI0_I_TRPI1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.27A","3fi0I-1i7oA:undetectable","3fi0I-1i7oA:24.78"],["3FI0_J_TRPJ1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.29A","3fi0J-1i7oA:0.0","3fi0J-1i7oA:24.78"],["3FI0_K_TRPK1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.31A","3fi0K-1i7oA:undetectable","3fi0K-1i7oA:24.78"],["3FI0_L_TRPL1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.29A","3fi0L-1i7oA:undetectable","3fi0L-1i7oA:24.78"],["3FI0_M_TRPM1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.27A","3fi0M-1i7oA:undetectable","3fi0M-1i7oA:24.78"],["3FI0_N_TRPN1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.30A","3fi0N-1i7oA:undetectable","3fi0N-1i7oA:24.78"],["3FI0_O_TRPO1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.27A","3fi0O-1i7oA:undetectable","3fi0O-1i7oA:24.78"],["3FI0_Q_TRPQ1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.27A","3fi0Q-1i7oA:undetectable","3fi0Q-1i7oA:24.78"],["3FI0_R_TRPR1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"VAL A 372;HIS A 347;ILE A 343;VAL A 415;VAL A 412","None","1.28A","3fi0R-1i7oA:undetectable","3fi0R-1i7oA:24.78"],["3OKX_A_SAMA201_0","YAEB-LIKE PROTEIN RPA0152","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"LEU A 375;TYR A 232;LEU A 368;THR A 364;LEU A 228","None","1.32A","3okxA-1i7oA:0.0","3okxA-1i7oA:20.24"],["3OKX_B_SAMB201_1","YAEB-LIKE PROTEIN RPA0152","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"LEU A 375;TYR A 232;LEU A 368;THR A 364;LEU A 228","None","1.32A","3okxB-1i7oA:0.0","3okxB-1i7oA:20.24"],["3SPK_A_TPVA100_2","HIV-1 PROTEASE;HIV-1 PROTEASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",4,"ALA A 153;GLY A  88;ILE A  69;THR A  65","None","0.87A","3spkB-1i7oA:undetectable","3spkB-1i7oA:15.68"],["3SUF_B_SUEB1201_2","NS3 PROTEASE, NS4A PROTEIN","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",3,"TYR A 313;LEU A 230;ARG A 311","None","0.72A","3sufB-1i7oA:0.0","3sufB-1i7oA:18.14"],["4DF3_A_SAMA301_0","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"ALA A 287;ALA A 295;VAL A 290;ALA A 300;ASP A 389","None","1.28A","4df3A-1i7oA:undetectable","4df3A-1i7oA:23.17"],["4DF3_B_SAMB301_0","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"ALA A 287;ALA A 295;VAL A 290;ALA A 300;ASP A 389","None","1.23A","4df3B-1i7oA:undetectable","4df3B-1i7oA:23.17"],["4FIA_A_0U9A601_1","CHOLESTEROL 24-HYDROXYLASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"TYR A 378;LEU A 379;PHE A 226;VAL A 249;ARG A 288","None","1.26A","4fiaA-1i7oA:0.0","4fiaA-1i7oA:24.59"],["4FIA_A_198A602_1","CHOLESTEROL 24-HYDROXYLASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"TYR A 378;LEU A 379;PHE A 226;VAL A 249;ARG A 288","None","1.26A","4fiaA-1i7oA:0.0","4fiaA-1i7oA:24.59"],["4O2B_B_LOCB503_1","TUBULIN ALPHA-1B CHAIN;TUBULIN BETA-2B CHAIN","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",3,"SER A 125;ALA A 123;VAL A 122","None","0.60A","4o2bA-1i7oA:undetectable","4o2bA-1i7oA:20.89"],["4OQR_A_2UOA502_1","CYP105AS1","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"ILE A  69;ALA A  67;THR A  65;VAL A 191;ALA A 193","None","1.08A","4oqrA-1i7oA:0.0","4oqrA-1i7oA:22.14"],["4QD3_A_5AEA201_1","PEPTIDYL-TRNA HYDROLASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"GLY A 114;VAL A  95;SER A  96;VAL A  60;LEU A  97","None","1.22A","4qd3A-1i7oA:undetectable","4qd3A-1i7oA:19.30"],["4QRC_A_0LIA802_2","FIBROBLAST GROWTH FACTOR RECEPTOR 4","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",4,"VAL A  77;ILE A  86;ALA A 153;LEU A  68","None","0.80A","4qrcA-1i7oA:undetectable","4qrcA-1i7oA:23.39"],["4UDA_A_DEXA1985_2","MINERALOCORTICOID RECEPTOR","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",4,"LEU A 225;LEU A 322;PHE A   6;THR A   4","None","1.11A","4udaA-1i7oA:undetectable","4udaA-1i7oA:21.78"],["5JSD_B_1GNB603_1","PHIAB6 TAILSPIKE;PHIAB6 TAILSPIKE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",3,"VAL A 249;GLU A 276;GLU A 278","None; CA A1001 (-3.1A); CA A1001 (-2.8A)","0.48A","5jsdB-1i7oA:0.0;5jsdC-1i7oA:0.0","5jsdB-1i7oA:18.60;5jsdC-1i7oA:18.60"],["5U4S_A_BEZA301_0","PUTATIVE SHORT CHAIN DEHYDROGENASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",4,"ASN A  43;ILE A 283;LEU A 385;MET A 383","None","0.99A","5u4sA-1i7oA:undetectable","5u4sA-1i7oA:21.99"],["5U4S_B_BEZB301_0","PUTATIVE SHORT CHAIN DEHYDROGENASE","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",4,"ASN A  43;ILE A 283;LEU A 385;MET A 383","None","1.00A","5u4sB-1i7oA:undetectable","5u4sB-1i7oA:21.99"],["5UUN_A_ACTA312_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",3,"ILE A 107;VAL A 249;PRO A 247","None","0.70A","5uunA-1i7oA:undetectable","5uunA-1i7oA:22.12"],["5VLM_A_CVIA301_0","REGULATORY PROTEIN TETR","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",5,"ALA A 377;SER A 380;LEU A 385;ILE A 283;TYR A 302","None","1.46A","5vlmA-1i7oA:undetectable","5vlmA-1i7oA:18.75"],["6B5V_B_ECLB1001_1","TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5;TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5","1i7o","4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE\/DECARBOXYLASE","Escherichia coli",4,"ALA A 253;PHE A 163;LEU A 160;ILE A 118","None","0.80A","6b5vA-1i7oA:undetectable;6b5vB-1i7oA:undetectable","6b5vA-1i7oA:12.47;6b5vB-1i7oA:12.47"]]