SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1i7p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 1i7p NADH-CYTOCHROME B5
REDUCTASE
(Rattus
norvegicus) 		4 / 7 THR A  56
TYR A 236
ASN A 209
LEU A 221
 None
 1.20A 2hzqA-1i7pA:
0.2		 2hzqA-1i7pA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1i7p NADH-CYTOCHROME B5
REDUCTASE
(Rattus
norvegicus) 		3 / 3 ARG A 218
ARG A 225
ASP A 246
 None
 0.99A 3wipG-1i7pA:
0.0
3wipH-1i7pA:
0.0		 3wipG-1i7pA:
20.42
3wipH-1i7pA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 1i7p NADH-CYTOCHROME B5
REDUCTASE
(Rattus
norvegicus) 		4 / 7 ILE A 190
LEU A 221
PHE A 207
GLY A 180
 None
 0.95A 4hajA-1i7pA:
undetectable		 4hajA-1i7pA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 1i7p NADH-CYTOCHROME B5
REDUCTASE
(Rattus
norvegicus) 		5 / 12 PRO A 275
ILE A 183
LEU A 217
PHE A 207
THR A  56
 None
 1.23A 5bykA-1i7pA:
0.9		 5bykA-1i7pA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 1i7p NADH-CYTOCHROME B5
REDUCTASE
(Rattus
norvegicus) 		4 / 6 TYR A 112
TYR A  93
GLY A 180
ASP A 239
 FAD  A 301 (-4.2A)
FAD  A 301 (-4.3A)
None
None
 1.28A 5emlA-1i7pA:
3.2		 5emlA-1i7pA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 1i7p NADH-CYTOCHROME B5
REDUCTASE
(Rattus
norvegicus) 		5 / 12 ASP A 100
ASP A 101
GLY A  71
PRO A  64
SER A  65
 None
 1.01A 5t2zA-1i7pA:
undetectable		 5t2zA-1i7pA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1i7p NADH-CYTOCHROME B5
REDUCTASE
(Rattus
norvegicus) 		4 / 8 THR A 181
GLY A 182
CYH A 273
GLY A 274
 FAD  A 301 (-3.3A)
None
FAD  A 301 ( 4.0A)
None
 0.51A 5vw5A-1i7pA:
19.4		 5vw5A-1i7pA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1i7p NADH-CYTOCHROME B5
REDUCTASE
(Rattus
norvegicus) 		4 / 8 THR A 181
GLY A 182
CYH A 273
GLY A 274
 FAD  A 301 (-3.3A)
None
FAD  A 301 ( 4.0A)
None
 0.49A 5vw9A-1i7pA:
19.5		 5vw9A-1i7pA:
23.15