SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1i7q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 1i7q TRPG
(Serratia
marcescens) 		4 / 8 GLU B  64
ILE B  81
GLU B  93
ALA B  94
 None
 0.74A 1a29A-1i7qB:
undetectable		 1a29A-1i7qB:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 5 LEU A  36
LEU A  38
SER A 310
GLY A 454
 None
 0.53A 1a4lC-1i7qA:
undetectable		 1a4lC-1i7qA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 1i7q TRPG
(Serratia
marcescens) 		4 / 6 LEU B 146
ASP B 162
LEU B  72
HIS B  88
 None
 1.14A 1errB-1i7qB:
0.0		 1errB-1i7qB:
18.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		11 / 11 GLU A 309
ILE A 326
GLY A 328
THR A 329
GLU A 361
HIS A 398
LEU A 426
ARG A 469
GLY A 485
GLU A 498
LYS A 502
 BEZ  A1501 (-3.8A)
BEZ  A1501 (-3.9A)
BEZ  A1501 (-3.3A)
BEZ  A1501 (-3.9A)
MG  A1701 ( 3.1A)
BEZ  A1501 ( 4.2A)
PYR  A1601 ( 4.7A)
PYR  A1601 ( 3.9A)
BEZ  A1501 (-3.8A)
MG  A1701 ( 2.6A)
BEZ  A1501 ( 2.9A)
 0.00A 1i7qA-1i7qA:
69.0		 1i7qA-1i7qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		6 / 11 GLU A 309
ILE A 326
THR A 329
HIS A 398
GLY A 483
GLU A 498
 BEZ  A1501 (-3.8A)
BEZ  A1501 (-3.9A)
BEZ  A1501 (-3.9A)
BEZ  A1501 ( 4.2A)
PYR  A1601 (-3.8A)
MG  A1701 ( 2.6A)
 1.42A 1i7qA-1i7qA:
69.0		 1i7qA-1i7qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I7Q_C_BEZC1502_0
(ANTHRANILATE
SYNTHASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		10 / 10 GLU A 309
ILE A 326
GLY A 328
THR A 329
GLU A 361
HIS A 398
ARG A 469
GLY A 485
GLU A 498
LYS A 502
 BEZ  A1501 (-3.8A)
BEZ  A1501 (-3.9A)
BEZ  A1501 (-3.3A)
BEZ  A1501 (-3.9A)
MG  A1701 ( 3.1A)
BEZ  A1501 ( 4.2A)
PYR  A1601 ( 3.9A)
BEZ  A1501 (-3.8A)
MG  A1701 ( 2.6A)
BEZ  A1501 ( 2.9A)
 0.15A 1i7qC-1i7qA:
65.7		 1i7qC-1i7qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I7Q_C_BEZC1502_0
(ANTHRANILATE
SYNTHASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		6 / 10 GLU A 309
ILE A 326
THR A 329
HIS A 398
GLY A 483
GLU A 498
 BEZ  A1501 (-3.8A)
BEZ  A1501 (-3.9A)
BEZ  A1501 (-3.9A)
BEZ  A1501 ( 4.2A)
PYR  A1601 (-3.8A)
MG  A1701 ( 2.6A)
 1.41A 1i7qC-1i7qA:
65.7		 1i7qC-1i7qA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 5 GLU A 102
GLY A 100
SER A  69
THR A  62
 None
 1.19A 1icrA-1i7qA:
0.0
1icrB-1i7qA:
0.0		 1icrA-1i7qA:
18.34
1icrB-1i7qA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 6 SER A  69
THR A  62
GLU A 102
GLY A 100
 None
 1.17A 1icuA-1i7qA:
0.0
1icuB-1i7qA:
0.0		 1icuA-1i7qA:
18.34
1icuB-1i7qA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 5 GLU A 102
GLY A 100
SER A  69
THR A  62
 None
 1.19A 1icvC-1i7qA:
0.0
1icvD-1i7qA:
0.0		 1icvC-1i7qA:
18.34
1icvD-1i7qA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 8 ALA A 416
LEU A 462
ALA A 311
THR A 464
 None
 0.93A 1ie4B-1i7qA:
undetectable
1ie4D-1i7qA:
undetectable		 1ie4B-1i7qA:
14.97
1ie4D-1i7qA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 6 SER A  69
THR A  62
GLU A 102
GLY A 100
 None
 1.17A 1kqbA-1i7qA:
0.0
1kqbB-1i7qA:
0.0		 1kqbA-1i7qA:
18.69
1kqbB-1i7qA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 5 GLU A 102
GLY A 100
SER A  69
THR A  62
 None
 1.16A 1kqbA-1i7qA:
undetectable
1kqbB-1i7qA:
undetectable		 1kqbA-1i7qA:
18.69
1kqbB-1i7qA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 6 GLU A 102
GLY A 100
SER A  69
THR A  62
 None
 1.17A 1kqbC-1i7qA:
0.0
1kqbD-1i7qA:
0.0		 1kqbC-1i7qA:
18.69
1kqbD-1i7qA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		3 / 3 ARG A 119
ARG A 117
ARG A 408
 None
 0.90A 1l7fA-1i7qA:
0.0		 1l7fA-1i7qA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 1i7q ANTHRANILATE
SYNTHASE
TRPG
(Serratia
marcescens;
Serratia
marcescens) 		3 / 3 ARG B  22
ARG B  43
ARG A 408
 None
 0.92A 1l7fA-1i7qB:
undetectable		 1l7fA-1i7qB:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		3 / 3 ARG A 119
ARG A 117
ARG A 408
 None
 0.92A 1l7hA-1i7qA:
0.0		 1l7hA-1i7qA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 1i7q ANTHRANILATE
SYNTHASE
TRPG
(Serratia
marcescens;
Serratia
marcescens) 		3 / 3 ARG B  22
ARG B  43
ARG A 408
 None
 0.92A 1l7hA-1i7qB:
undetectable		 1l7hA-1i7qB:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		5 / 9 VAL A 249
LEU A 252
VAL A 265
GLY A 483
ALA A 484
 None
None
None
PYR  A1601 (-3.8A)
BEZ  A1501 (-4.2A)
 1.28A 1pxxB-1i7qA:
undetectable		 1pxxB-1i7qA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		5 / 10 VAL A 249
LEU A 252
VAL A 265
GLY A 483
ALA A 484
 None
None
None
PYR  A1601 (-3.8A)
BEZ  A1501 (-4.2A)
 1.28A 1pxxD-1i7qA:
0.0		 1pxxD-1i7qA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 8 PHE A 158
PHE A 173
ALA A 126
LEU A 121
 None
 1.03A 1x8vA-1i7qA:
undetectable		 1x8vA-1i7qA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1i7q TRPG
(Serratia
marcescens) 		4 / 5 ALA B 158
PHE B 169
ASN B 149
ASP B 116
 None
 1.14A 1yc2D-1i7qB:
4.3		 1yc2D-1i7qB:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZWP_A_NIMA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1i7q TRPG
(Serratia
marcescens) 		4 / 5 LEU B 184
GLY B 119
TRP B 191
ASP B 116
 None
 1.12A 1zwpA-1i7qB:
0.0		 1zwpA-1i7qB:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		9 / 11 GLU A 309
GLY A 328
THR A 329
GLU A 361
HIS A 398
ARG A 469
GLY A 485
GLU A 498
LYS A 502
 BEZ  A1501 (-3.8A)
BEZ  A1501 (-3.3A)
BEZ  A1501 (-3.9A)
MG  A1701 ( 3.1A)
BEZ  A1501 ( 4.2A)
PYR  A1601 ( 3.9A)
BEZ  A1501 (-3.8A)
MG  A1701 ( 2.6A)
BEZ  A1501 ( 2.9A)
 0.31A 2fn1A-1i7qA:
42.3		 2fn1A-1i7qA:
29.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		5 / 11 GLU A 309
THR A 329
HIS A 398
GLY A 483
GLU A 498
 BEZ  A1501 (-3.8A)
BEZ  A1501 (-3.9A)
BEZ  A1501 ( 4.2A)
PYR  A1601 (-3.8A)
MG  A1701 ( 2.6A)
 1.35A 2fn1A-1i7qA:
42.3		 2fn1A-1i7qA:
29.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		7 / 11 GLY A 328
THR A 329
GLU A 358
HIS A 398
ARG A 469
GLU A 498
LYS A 502
 BEZ  A1501 (-3.3A)
BEZ  A1501 (-3.9A)
MG  A1701 ( 4.3A)
BEZ  A1501 ( 4.2A)
PYR  A1601 ( 3.9A)
MG  A1701 ( 2.6A)
BEZ  A1501 ( 2.9A)
 1.45A 2fn1A-1i7qA:
42.3		 2fn1A-1i7qA:
29.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		10 / 11 GLU A 309
GLY A 328
THR A 329
GLU A 361
HIS A 398
THR A 425
ARG A 469
GLY A 485
GLU A 498
LYS A 502
 BEZ  A1501 (-3.8A)
BEZ  A1501 (-3.3A)
BEZ  A1501 (-3.9A)
MG  A1701 ( 3.1A)
BEZ  A1501 ( 4.2A)
BEZ  A1501 (-4.7A)
PYR  A1601 ( 3.9A)
BEZ  A1501 (-3.8A)
MG  A1701 ( 2.6A)
BEZ  A1501 ( 2.9A)
 0.41A 2fn1B-1i7qA:
41.7		 2fn1B-1i7qA:
29.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		5 / 11 GLU A 309
THR A 329
HIS A 398
GLY A 483
GLU A 498
 BEZ  A1501 (-3.8A)
BEZ  A1501 (-3.9A)
BEZ  A1501 ( 4.2A)
PYR  A1601 (-3.8A)
MG  A1701 ( 2.6A)
 1.36A 2fn1B-1i7qA:
41.7		 2fn1B-1i7qA:
29.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		7 / 11 GLY A 328
THR A 329
GLU A 358
HIS A 398
ARG A 469
GLU A 498
LYS A 502
 BEZ  A1501 (-3.3A)
BEZ  A1501 (-3.9A)
MG  A1701 ( 4.3A)
BEZ  A1501 ( 4.2A)
PYR  A1601 ( 3.9A)
MG  A1701 ( 2.6A)
BEZ  A1501 ( 2.9A)
 1.39A 2fn1B-1i7qA:
41.7		 2fn1B-1i7qA:
29.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 1i7q ANTHRANILATE
SYNTHASE
TRPG
(Serratia
marcescens;
Serratia
marcescens) 		3 / 3 ARG A 375
ARG B  32
ARG A 117
 None
 1.13A 2jb7A-1i7qA:
1.0
2jb7B-1i7qA:
0.8
2jb7C-1i7qA:
0.9		 2jb7A-1i7qA:
15.46
2jb7B-1i7qA:
15.46
2jb7C-1i7qA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 1i7q ANTHRANILATE
SYNTHASE
TRPG
(Serratia
marcescens;
Serratia
marcescens) 		3 / 3 ARG B  32
ARG A 117
ARG A 375
 None
 1.09A 2jb7A-1i7qB:
0.0
2jb7B-1i7qB:
0.0
2jb7C-1i7qB:
0.0		 2jb7A-1i7qB:
22.44
2jb7B-1i7qB:
22.44
2jb7C-1i7qB:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 1i7q TRPG
(Serratia
marcescens) 		4 / 5 LEU B 146
ASP B 162
LEU B  72
HIS B  88
 None
 1.10A 2jfaA-1i7qB:
0.0		 2jfaA-1i7qB:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_E_MTXE621_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		5 / 12 ALA A  96
LEU A 103
ASP A  85
LEU A  84
ILE A  61
 None
 1.01A 2oipE-1i7qA:
undetectable		 2oipE-1i7qA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)		 1i7q TRPG
(Serratia
marcescens) 		4 / 6 ARG B 132
PHE B 171
ILE B 113
PHE B 121
 None
 1.10A 2qeiA-1i7qB:
0.0		 2qeiA-1i7qB:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 1i7q TRPG
(Serratia
marcescens) 		4 / 5 LEU B 146
ASP B 162
LEU B  72
HIS B  88
 None
 1.14A 2qxsA-1i7qB:
0.0		 2qxsA-1i7qB:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 1i7q TRPG
(Serratia
marcescens) 		4 / 5 LEU B 146
ASP B 162
LEU B  72
HIS B  88
 None
 1.14A 2qxsB-1i7qB:
0.0		 2qxsB-1i7qB:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		5 / 8 ALA A  87
LEU A  88
LEU A 103
VAL A  70
ILE A  61
 None
 1.20A 2uxpA-1i7qA:
undetectable		 2uxpA-1i7qA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1i7q TRPG
(Serratia
marcescens) 		5 / 10 GLY B 138
GLN B  89
HIS B 134
VAL B 148
VAL B 159
 None
GLU  B1401 (-3.1A)
None
None
None
 1.34A 3fhjA-1i7qB:
2.3		 3fhjA-1i7qB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1i7q TRPG
(Serratia
marcescens) 		5 / 10 GLY B 138
GLN B  89
HIS B 134
VAL B 148
VAL B 159
 None
GLU  B1401 (-3.1A)
None
None
None
 1.30A 3fhjB-1i7qB:
undetectable		 3fhjB-1i7qB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1i7q TRPG
(Serratia
marcescens) 		5 / 10 GLY B 138
GLN B  89
HIS B 134
VAL B 148
VAL B 159
 None
GLU  B1401 (-3.1A)
None
None
None
 1.29A 3fhjC-1i7qB:
undetectable		 3fhjC-1i7qB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1i7q TRPG
(Serratia
marcescens) 		5 / 10 GLY B 138
GLN B  89
HIS B 134
VAL B 148
VAL B 159
 None
GLU  B1401 (-3.1A)
None
None
None
 1.33A 3fhjE-1i7qB:
undetectable		 3fhjE-1i7qB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1i7q TRPG
(Serratia
marcescens) 		5 / 9 GLY B 138
GLN B  89
HIS B 134
VAL B 148
VAL B 159
 None
GLU  B1401 (-3.1A)
None
None
None
 1.37A 3fi0A-1i7qB:
undetectable		 3fi0A-1i7qB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1i7q TRPG
(Serratia
marcescens) 		5 / 9 GLY B 138
GLN B  89
HIS B 134
VAL B 148
VAL B 159
 None
GLU  B1401 (-3.1A)
None
None
None
 1.34A 3fi0C-1i7qB:
2.2		 3fi0C-1i7qB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1i7q TRPG
(Serratia
marcescens) 		5 / 9 GLY B 138
GLN B  89
HIS B 134
VAL B 148
VAL B 159
 None
GLU  B1401 (-3.1A)
None
None
None
 1.34A 3fi0H-1i7qB:
2.3		 3fi0H-1i7qB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1i7q TRPG
(Serratia
marcescens) 		5 / 9 GLY B 138
GLN B  89
HIS B 134
VAL B 148
VAL B 159
 None
GLU  B1401 (-3.1A)
None
None
None
 1.40A 3fi0K-1i7qB:
undetectable		 3fi0K-1i7qB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1i7q TRPG
(Serratia
marcescens) 		5 / 9 GLY B 138
GLN B  89
HIS B 134
VAL B 148
VAL B 159
 None
GLU  B1401 (-3.1A)
None
None
None
 1.41A 3fi0L-1i7qB:
undetectable		 3fi0L-1i7qB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1i7q TRPG
(Serratia
marcescens) 		5 / 9 GLY B 138
GLN B  89
HIS B 134
VAL B 148
VAL B 159
 None
GLU  B1401 (-3.1A)
None
None
None
 1.34A 3fi0N-1i7qB:
2.4		 3fi0N-1i7qB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1i7q TRPG
(Serratia
marcescens) 		5 / 9 GLY B 138
GLN B  89
HIS B 134
VAL B 148
VAL B 159
 None
GLU  B1401 (-3.1A)
None
None
None
 1.36A 3fi0O-1i7qB:
undetectable		 3fi0O-1i7qB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		3 / 3 LEU A  37
LEU A  53
ARG A  18
 None
 0.63A 3hcnB-1i7qA:
undetectable		 3hcnB-1i7qA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 1i7q TRPG
(Serratia
marcescens) 		3 / 3 ILE B  30
VAL B  18
ARG B  22
 None
 0.61A 3p73A-1i7qB:
undetectable		 3p73A-1i7qB:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		9 / 12 GLU A 309
ILE A 326
GLY A 328
THR A 329
GLU A 361
HIS A 398
ARG A 469
GLU A 498
LYS A 502
 BEZ  A1501 (-3.8A)
BEZ  A1501 (-3.9A)
BEZ  A1501 (-3.3A)
BEZ  A1501 (-3.9A)
MG  A1701 ( 3.1A)
BEZ  A1501 ( 4.2A)
PYR  A1601 ( 3.9A)
MG  A1701 ( 2.6A)
BEZ  A1501 ( 2.9A)
 0.41A 3r75A-1i7qA:
37.8		 3r75A-1i7qA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		7 / 12 GLY A 328
THR A 329
GLU A 358
HIS A 398
ARG A 469
GLU A 498
LYS A 502
 BEZ  A1501 (-3.3A)
BEZ  A1501 (-3.9A)
MG  A1701 ( 4.3A)
BEZ  A1501 ( 4.2A)
PYR  A1601 ( 3.9A)
MG  A1701 ( 2.6A)
BEZ  A1501 ( 2.9A)
 1.44A 3r75A-1i7qA:
37.8		 3r75A-1i7qA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		9 / 12 GLU A 309
ILE A 326
GLY A 328
THR A 329
GLU A 361
HIS A 398
ARG A 469
GLU A 498
LYS A 502
 BEZ  A1501 (-3.8A)
BEZ  A1501 (-3.9A)
BEZ  A1501 (-3.3A)
BEZ  A1501 (-3.9A)
MG  A1701 ( 3.1A)
BEZ  A1501 ( 4.2A)
PYR  A1601 ( 3.9A)
MG  A1701 ( 2.6A)
BEZ  A1501 ( 2.9A)
 0.41A 3r75B-1i7qA:
37.1		 3r75B-1i7qA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		7 / 12 GLY A 328
THR A 329
GLU A 358
HIS A 398
ARG A 469
GLU A 498
LYS A 502
 BEZ  A1501 (-3.3A)
BEZ  A1501 (-3.9A)
MG  A1701 ( 4.3A)
BEZ  A1501 ( 4.2A)
PYR  A1601 ( 3.9A)
MG  A1701 ( 2.6A)
BEZ  A1501 ( 2.9A)
 1.45A 3r75B-1i7qA:
37.1		 3r75B-1i7qA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		9 / 11 GLU A 309
ILE A 326
GLY A 328
THR A 329
GLU A 361
HIS A 398
ARG A 469
GLU A 498
LYS A 502
 BEZ  A1501 (-3.8A)
BEZ  A1501 (-3.9A)
BEZ  A1501 (-3.3A)
BEZ  A1501 (-3.9A)
MG  A1701 ( 3.1A)
BEZ  A1501 ( 4.2A)
PYR  A1601 ( 3.9A)
MG  A1701 ( 2.6A)
BEZ  A1501 ( 2.9A)
 0.43A 3r76A-1i7qA:
38.0		 3r76A-1i7qA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		7 / 11 GLY A 328
THR A 329
GLU A 358
HIS A 398
ARG A 469
GLU A 498
LYS A 502
 BEZ  A1501 (-3.3A)
BEZ  A1501 (-3.9A)
MG  A1701 ( 4.3A)
BEZ  A1501 ( 4.2A)
PYR  A1601 ( 3.9A)
MG  A1701 ( 2.6A)
BEZ  A1501 ( 2.9A)
 1.46A 3r76A-1i7qA:
38.0		 3r76A-1i7qA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		9 / 11 GLU A 309
ILE A 326
GLY A 328
THR A 329
GLU A 361
HIS A 398
ARG A 469
GLU A 498
LYS A 502
 BEZ  A1501 (-3.8A)
BEZ  A1501 (-3.9A)
BEZ  A1501 (-3.3A)
BEZ  A1501 (-3.9A)
MG  A1701 ( 3.1A)
BEZ  A1501 ( 4.2A)
PYR  A1601 ( 3.9A)
MG  A1701 ( 2.6A)
BEZ  A1501 ( 2.9A)
 0.44A 3r76B-1i7qA:
37.2		 3r76B-1i7qA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		6 / 11 GLY A 328
THR A 329
GLU A 358
HIS A 398
GLU A 498
LYS A 502
 BEZ  A1501 (-3.3A)
BEZ  A1501 (-3.9A)
MG  A1701 ( 4.3A)
BEZ  A1501 ( 4.2A)
MG  A1701 ( 2.6A)
BEZ  A1501 ( 2.9A)
 1.46A 3r76B-1i7qA:
37.2		 3r76B-1i7qA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 5 ASP A 172
SER A  69
VAL A  68
GLY A  65
 None
 1.01A 3rxhA-1i7qA:
undetectable		 3rxhA-1i7qA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 5 ARG A 101
LEU A 103
VAL A  70
ASP A  85
 None
 1.12A 3ufnA-1i7qA:
0.0
3ufnB-1i7qA:
undetectable		 3ufnA-1i7qA:
12.40
3ufnB-1i7qA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 8 LEU A 177
VAL A 134
LEU A   8
ALA A 458
 None
 0.94A 3uniB-1i7qA:
0.0		 3uniB-1i7qA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		3 / 3 PHE A 301
ASP A 475
ARG A 169
 None
 0.79A 4eahF-1i7qA:
undetectable		 4eahF-1i7qA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		3 / 3 PHE A 301
ASP A 475
ARG A 169
 None
 0.79A 4eahG-1i7qA:
0.0		 4eahG-1i7qA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 1i7q TRPG
(Serratia
marcescens) 		3 / 3 LYS B 195
ARG B 165
TRP B 191
 None
 0.74A 4i90A-1i7qB:
0.0		 4i90A-1i7qB:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		3 / 3 ARG A 269
ASP A 167
ARG A 442
 None
 1.02A 4mx0A-1i7qA:
undetectable		 4mx0A-1i7qA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 1i7q TRPG
(Serratia
marcescens) 		5 / 12 LEU B 184
GLY B 181
ILE B  84
GLN B  20
LEU B  17
 None
 1.15A 4o5fA-1i7qB:
undetectable
4o5fB-1i7qB:
undetectable		 4o5fA-1i7qB:
22.15
4o5fB-1i7qB:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 1i7q TRPG
(Serratia
marcescens) 		5 / 12 GLN B  20
LEU B  17
LEU B 184
GLY B 181
ILE B  84
 None
 1.18A 4o5fA-1i7qB:
undetectable
4o5fB-1i7qB:
undetectable		 4o5fA-1i7qB:
22.15
4o5fB-1i7qB:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		5 / 10 LEU A   8
LEU A 131
LEU A 146
LEU A 177
PHE A 198
 None
 1.06A 4odoA-1i7qA:
undetectable		 4odoA-1i7qA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		5 / 10 LEU A   8
LEU A 131
LEU A 146
LEU A 177
PHE A 198
 None
 1.08A 4odoB-1i7qA:
undetectable		 4odoB-1i7qA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 5 GLY A 328
THR A 329
GLY A 485
GLU A 358
 BEZ  A1501 (-3.3A)
BEZ  A1501 (-3.9A)
BEZ  A1501 (-3.8A)
MG  A1701 ( 4.3A)
 0.86A 4v20A-1i7qA:
undetectable		 4v20A-1i7qA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 6 ALA A 195
GLN A 194
LEU A  11
LEU A   8
 None
 1.19A 4xoyA-1i7qA:
undetectable		 4xoyA-1i7qA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 6 ALA A 195
GLN A 194
LEU A  11
LEU A   8
 None
 1.28A 4xp3A-1i7qA:
undetectable		 4xp3A-1i7qA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_1
(PROLINE--TRNA LIGASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 4 THR A 425
GLU A 309
THR A 329
HIS A 398
 BEZ  A1501 (-4.7A)
BEZ  A1501 (-3.8A)
BEZ  A1501 (-3.9A)
BEZ  A1501 ( 4.2A)
 1.37A 4ydqA-1i7qA:
1.3		 4ydqA-1i7qA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		5 / 11 ALA A 178
GLY A 147
LEU A  24
LEU A 215
LEU A 182
 None
 1.06A 4zmeA-1i7qA:
undetectable		 4zmeA-1i7qA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 1i7q TRPG
(Serratia
marcescens) 		5 / 12 LEU B 184
GLY B 181
ILE B  84
GLN B  20
LEU B  17
 None
 1.13A 5b8hA-1i7qB:
undetectable
5b8hB-1i7qB:
undetectable		 5b8hA-1i7qB:
21.65
5b8hB-1i7qB:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 1i7q TRPG
(Serratia
marcescens) 		5 / 12 GLN B  20
LEU B  17
LEU B 184
GLY B 181
ILE B  84
 None
 1.14A 5b8hA-1i7qB:
undetectable
5b8hB-1i7qB:
undetectable		 5b8hA-1i7qB:
21.65
5b8hB-1i7qB:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		5 / 12 ARG A 402
SER A  40
TYR A 324
TYR A 455
LEU A 462
 None
 1.41A 5czyA-1i7qA:
0.0		 5czyA-1i7qA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1i7q TRPG
(Serratia
marcescens) 		4 / 8 SER B  24
ALA B  23
HIS B  26
LEU B 185
 None
 1.01A 5dzkd-1i7qB:
undetectable
5dzkr-1i7qB:
undetectable		 5dzkd-1i7qB:
24.47
5dzkr-1i7qB:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_1
(AMINOACYL-TRNA
SYNTHETASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 4 THR A 425
GLU A 309
THR A 329
HIS A 398
 BEZ  A1501 (-4.7A)
BEZ  A1501 (-3.8A)
BEZ  A1501 (-3.9A)
BEZ  A1501 ( 4.2A)
 1.38A 5f9zA-1i7qA:
undetectable		 5f9zA-1i7qA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_1
(AMINOACYL-TRNA
SYNTHETASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 4 THR A 425
GLU A 309
THR A 329
HIS A 398
 BEZ  A1501 (-4.7A)
BEZ  A1501 (-3.8A)
BEZ  A1501 (-3.9A)
BEZ  A1501 ( 4.2A)
 1.37A 5f9zB-1i7qA:
1.0		 5f9zB-1i7qA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1i7q TRPG
(Serratia
marcescens) 		5 / 8 ARG B  74
ALA B  37
LEU B  75
LEU B   7
LEU B  53
 None
 1.29A 5jqbA-1i7qB:
1.3
5jqbB-1i7qB:
undetectable		 5jqbA-1i7qB:
20.61
5jqbB-1i7qB:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1i7q TRPG
(Serratia
marcescens) 		5 / 12 GLU B 174
LEU B  86
GLY B  83
LEU B   7
ASN B  33
 None
GLU  B1401 (-4.0A)
None
None
None
 1.23A 5kbwA-1i7qB:
undetectable		 5kbwA-1i7qB:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		5 / 12 LEU A 149
GLY A 454
TYR A 455
PHE A 124
LEU A 154
 None
 1.38A 5kklB-1i7qA:
undetectable		 5kklB-1i7qA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 1i7q TRPG
(Serratia
marcescens) 		5 / 12 GLY B  36
GLN B  78
LEU B  53
LEU B  79
LEU B   5
 None
 1.27A 5nwwA-1i7qB:
0.0		 5nwwA-1i7qB:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		3 / 3 GLY A 328
LEU A 399
HIS A 362
 BEZ  A1501 (-3.3A)
None
None
 0.63A 5u63A-1i7qA:
undetectable		 5u63A-1i7qA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		3 / 3 GLY A 328
LEU A 399
HIS A 362
 BEZ  A1501 (-3.3A)
None
None
 0.68A 5u63B-1i7qA:
undetectable		 5u63B-1i7qA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 1i7q ANTHRANILATE
SYNTHASE
TRPG
(Serratia
marcescens) 		4 / 5 ASP B  19
PRO B  57
ARG A 375
THR B  14
 None
GLU  B1401 (-3.8A)
None
None
 1.02A 5uxcA-1i7qB:
0.0		 5uxcA-1i7qB:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		3 / 3 ARG A 504
ARG A 469
ARG A 332
 None
PYR  A1601 ( 3.9A)
None
 0.72A 5vcgA-1i7qA:
0.0		 5vcgA-1i7qA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 1i7q ANTHRANILATE
SYNTHASE
TRPG
(Serratia
marcescens;
Serratia
marcescens) 		4 / 8 ARG A 408
GLN A 378
VAL B  18
ASP A 113
 None
 1.17A 5vlmF-1i7qA:
undetectable		 5vlmF-1i7qA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 1i7q ANTHRANILATE
SYNTHASE
TRPG
(Serratia
marcescens;
Serratia
marcescens) 		5 / 12 LEU B  53
ILE B  81
VAL A 432
GLY B 168
CYH B 167
 None
 1.26A 6a7pA-1i7qB:
0.5		 6a7pA-1i7qB:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 5 VAL A 144
LEU A  80
VAL A  70
LEU A  73
 None
 0.98A 6bqgA-1i7qA:
0.0		 6bqgA-1i7qA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		5 / 12 ALA A 458
LEU A   8
VAL A  13
LEU A 177
ALA A  58
 None
 1.11A 6djzC-1i7qA:
0.0		 6djzC-1i7qA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 5 LEU A 127
LEU A 154
THR A  67
ARG A 169
 None
 0.98A 6ew0F-1i7qA:
0.0		 6ew0F-1i7qA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 6 LEU A 127
LEU A 154
THR A  67
ARG A 169
 None
 0.98A 6ew0G-1i7qA:
0.0		 6ew0G-1i7qA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 1i7q TRPG
(Serratia
marcescens) 		3 / 3 VAL B  39
GLU B  38
ILE B  35
 None
 0.65A 6f7lB-1i7qB:
undetectable		 6f7lB-1i7qB:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		3 / 3 VAL A 404
ALA A 385
GLN A 320
 None
 0.59A 6gb9A-1i7qA:
undetectable		 6gb9A-1i7qA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 8 ASP A 497
HIS A 398
ARG A 494
GLU A 351
 None
BEZ  A1501 ( 4.2A)
None
None
 1.24A 6mn4A-1i7qA:
0.0		 6mn4A-1i7qA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1i7q ANTHRANILATE
SYNTHASE
(Serratia
marcescens) 		4 / 8 ASP A 497
HIS A 398
ARG A 494
GLU A 351
 None
BEZ  A1501 ( 4.2A)
None
None
 1.26A 6mn4B-1i7qA:
0.0		 6mn4B-1i7qA:
22.35