SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1i84'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 5 GLU S 148
ARG S 788
ASP S 789
LEU S 790
 None
 1.25A 1n13B-1i84S:
0.0
1n13C-1i84S:
undetectable		 1n13B-1i84S:
6.96
1n13C-1i84S:
4.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		5 / 12 PHE S 315
LEU S 613
VAL S 609
PHE S 398
ALA S 429
 None
 1.30A 1q23A-1i84S:
0.0
1q23B-1i84S:
0.0		 1q23A-1i84S:
10.17
1q23B-1i84S:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 8 TYR S 663
TYR S 270
LEU S 674
MET S 671
 None
 1.36A 1uw6A-1i84S:
0.0
1uw6B-1i84S:
undetectable		 1uw6A-1i84S:
10.31
1uw6B-1i84S:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 8 TYR S 663
TYR S 270
LEU S 674
MET S 671
 None
 1.37A 1uw6D-1i84S:
0.0
1uw6E-1i84S:
0.0		 1uw6D-1i84S:
10.31
1uw6E-1i84S:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 8 TYR S 663
TYR S 270
LEU S 674
MET S 671
 None
 1.36A 1uw6G-1i84S:
undetectable
1uw6H-1i84S:
undetectable		 1uw6G-1i84S:
10.31
1uw6H-1i84S:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 8 TYR S 663
TYR S 270
LEU S 674
MET S 671
 None
 1.38A 1uw6P-1i84S:
undetectable
1uw6Q-1i84S:
0.0		 1uw6P-1i84S:
10.31
1uw6Q-1i84S:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 8 LEU S 674
MET S 671
TYR S 663
TYR S 270
 None
 1.38A 1uw6P-1i84S:
undetectable
1uw6T-1i84S:
0.0		 1uw6P-1i84S:
10.31
1uw6T-1i84S:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		5 / 12 VAL S 387
PHE S 398
ILE S 393
VAL S 609
LEU S 430
 None
 1.11A 2jn3A-1i84S:
0.3		 2jn3A-1i84S:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 6 ILE S 153
CYH S 175
LEU S 461
ILE S 463
 None
 1.01A 2q83B-1i84S:
0.0		 2q83B-1i84S:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 6 ILE S 769
CYH S 753
LEU S 781
ILE S 725
 None
 0.94A 2q83B-1i84S:
0.0		 2q83B-1i84S:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 6 LEU S 781
LEU S 784
ILE S 725
ARG S 733
 None
 0.89A 2rlfC-1i84S:
2.5
2rlfD-1i84S:
0.9		 2rlfC-1i84S:
3.99
2rlfD-1i84S:
3.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDM_B_AGGB1462_1
(INTEGRIN ALPHA-IIB
INTEGRIN BETA-3)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		5 / 12 LEU S 670
SER S 179
TYR S 586
ASN S 483
ALA S 467
 None
 1.49A 2vdmA-1i84S:
0.0
2vdmB-1i84S:
undetectable		 2vdmA-1i84S:
16.22
2vdmB-1i84S:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		5 / 12 GLY S 212
TYR S 154
VAL S 197
SER S 199
ASP S 139
 None
 1.46A 2vqyA-1i84S:
undetectable		 2vqyA-1i84S:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 8 LEU S 362
PHE S 367
MET S 378
PHE S 398
 None
 0.75A 2weyB-1i84S:
undetectable		 2weyB-1i84S:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 8 LEU S 362
VAL S 359
VAL S 621
LEU S 613
 None
 0.85A 2zujA-1i84S:
undetectable		 2zujA-1i84S:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 8 GLY S 588
GLU S 487
ASN S 483
ILE S 471
 None
 0.90A 3aodA-1i84S:
undetectable		 3aodA-1i84S:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 8 SER S 246
GLU S 185
ILE S 191
ALA S 195
 None
 0.95A 3aodA-1i84S:
undetectable		 3aodA-1i84S:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		3 / 3 TYR S 127
TYR S 108
ILE S 124
 None
 0.74A 3eteA-1i84S:
0.0
3eteB-1i84S:
undetectable		 3eteA-1i84S:
18.60
3eteB-1i84S:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		3 / 3 ASN S 228
ASP S 465
ARG S 285
 None
 0.82A 3k13C-1i84S:
undetectable		 3k13C-1i84S:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 7 LEU S 705
GLN S 490
PHE S 493
LEU S 519
 None
 0.87A 3qeoB-1i84S:
undetectable		 3qeoB-1i84S:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		3 / 3 GLY S 180
GLY S 182
THR S 184
 None
 0.45A 3si7B-1i84S:
undetectable		 3si7B-1i84S:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		3 / 3 GLN S 211
GLU S 135
LYS S 211
 None
 1.18A 3su9A-1i84S:
0.0		 3su9A-1i84S:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 5 GLU S 178
GLY S 177
TYR S 586
GLN S 490
 None
 1.26A 3w9tD-1i84S:
0.0		 3w9tD-1i84S:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 5 GLU S 178
GLY S 177
TYR S 586
GLN S 490
 None
 1.21A 3w9tE-1i84S:
0.0		 3w9tE-1i84S:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 5 GLU S 178
GLY S 177
TYR S 586
GLN S 490
 None
 1.22A 3w9tG-1i84S:
0.0		 3w9tG-1i84S:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 6 LEU S 540
PHE S 555
LEU S 559
PHE S 569
 None
 0.93A 3wg7P-1i84S:
undetectable
3wg7W-1i84S:
1.7		 3wg7P-1i84S:
10.90
3wg7W-1i84S:
3.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 5 ARG S 437
VAL S 609
LEU S 612
SER S 611
 None
 1.28A 4e1gA-1i84S:
0.0		 4e1gA-1i84S:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 5 VAL S 609
LEU S 362
VAL S 387
PHE S 398
 None
 0.99A 4lb0B-1i84S:
0.0		 4lb0B-1i84S:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 8 GLU S 529
GLN S 522
MET S 497
THR S 496
 None
 1.07A 4lnwA-1i84S:
undetectable		 4lnwA-1i84S:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		3 / 3 HIS S  42
VAL S  68
LEU S  61
 None
 0.67A 4m2vA-1i84S:
undetectable		 4m2vA-1i84S:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 6 ASN S 708
GLU S 703
GLU S  97
GLU S 712
 None
 1.43A 4mi4A-1i84S:
0.0		 4mi4A-1i84S:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		5 / 12 LEU S 450
ALA S 227
ILE S 254
ALA S 265
ILE S 463
 None
 0.86A 4o2bD-1i84S:
undetectable		 4o2bD-1i84S:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		3 / 3 LEU S 541
MET S 602
TYR S 663
 None
 0.93A 4p6xG-1i84S:
undetectable		 4p6xG-1i84S:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 5 VAL S 122
VAL S  86
TYR S 108
ARG S 715
 None
 1.08A 4r7iA-1i84S:
undetectable		 4r7iA-1i84S:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 7 ASP S 465
ILE S 466
GLY S 468
THR S 184
 None
 1.12A 4zxiA-1i84S:
2.7		 4zxiA-1i84S:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		6 / 12 THR S 269
GLY S 235
LEU S 443
ALA S 277
ARG S 276
LYS S 432
 None
 1.45A 5c0oG-1i84S:
undetectable		 5c0oG-1i84S:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 5 LEU S 760
PHE S 776
ILE S 757
ILE S 774
 None
 1.04A 5dzk4-1i84S:
undetectable
5dzkg-1i84S:
undetectable
5dzkm-1i84S:
0.0
5dzkn-1i84S:
0.0		 5dzk4-1i84S:
0.89
5dzkg-1i84S:
11.39
5dzkm-1i84S:
11.06
5dzkn-1i84S:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		5 / 12 ILE S 262
GLY S 264
PHE S 460
TYR S 161
ALA S 198
 None
 1.08A 5n0oA-1i84S:
undetectable		 5n0oA-1i84S:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		5 / 12 ILE S 262
GLY S 264
PHE S 460
TYR S 161
ALA S 198
 None
 1.09A 5n0oB-1i84S:
undetectable		 5n0oB-1i84S:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		5 / 12 ILE S 262
GLY S 264
PHE S 460
TYR S 161
ALA S 198
 None
 1.09A 5n0rA-1i84S:
0.1		 5n0rA-1i84S:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		5 / 12 ILE S 262
GLY S 264
PHE S 460
TYR S 161
ALA S 198
 None
 1.10A 5n0tA-1i84S:
0.0		 5n0tA-1i84S:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		5 / 12 ILE S 262
GLY S 264
PHE S 460
TYR S 161
ALA S 198
 None
 1.11A 5n0wA-1i84S:
0.1		 5n0wA-1i84S:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		5 / 12 ILE S 262
GLY S 264
PHE S 460
TYR S 161
ALA S 198
 None
 1.08A 5n0xA-1i84S:
0.2		 5n0xA-1i84S:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		5 / 12 ILE S 262
GLY S 264
PHE S 460
TYR S 161
ALA S 198
 None
 1.08A 5n0xB-1i84S:
1.4		 5n0xB-1i84S:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		5 / 12 GLY S  43
SER S  39
GLN S  62
GLU S  45
LEU S  61
 None
 1.27A 5nwwA-1i84S:
0.3		 5nwwA-1i84S:
3.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 6 ARG S 437
THR S 610
ASP S 607
LEU S 605
 None
 1.15A 5tdzA-1i84S:
0.1		 5tdzA-1i84S:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 6 ILE S 267
ILE S 289
PHE S 248
PHE S 332
 None
 1.07A 5vkqA-1i84S:
0.0
5vkqB-1i84S:
0.0		 5vkqA-1i84S:
22.27
5vkqB-1i84S:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 6 ILE S 267
ILE S 289
PHE S 248
PHE S 332
 None
 1.05A 5vkqB-1i84S:
0.3
5vkqC-1i84S:
1.3		 5vkqB-1i84S:
22.27
5vkqC-1i84S:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		4 / 7 GLN S 361
GLY S 363
GLN S 418
ASP S 424
 None
 1.05A 5vlmC-1i84S:
0.7		 5vlmC-1i84S:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN
(Gallus
gallus) 		3 / 3 GLN S 361
TYR S 313
ASN S 364
 None
 0.89A 6dwdC-1i84S:
0.0		 6dwdC-1i84S:
19.19