SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1i8o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YHA_E_MZME303_1 (ALPHA-CARBONIC ANHYDRASE)	1i8o	CYTOCHROME C2 (Rhodopseudomonas palustris)	5 / 12	VAL A 107 VAL A 106 LEU A 67 ALA A 68 PRO A 70	None HEC A 115 ( 4.9A) HEC A 115 (-4.6A) None None	1.19A	4yhaE-1i8oA: undetectable	4yhaE-1i8oA: 19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	1i8o	CYTOCHROME C2 (Rhodopseudomonas palustris)	5 / 10	VAL A 107 VAL A 106 LEU A 67 ALA A 68 PRO A 70	None HEC A 115 ( 4.9A) HEC A 115 (-4.6A) None None	1.31A	5tt3A-1i8oA: undetectable	5tt3A-1i8oA: 19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	1i8o	CYTOCHROME C2 (Rhodopseudomonas palustris)	5 / 10	VAL A 107 VAL A 106 LEU A 67 ALA A 68 PRO A 70	None HEC A 115 ( 4.9A) HEC A 115 (-4.6A) None None	1.23A	5tt3C-1i8oA: undetectable	5tt3C-1i8oA: 19.23