SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1i9c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CLB_B_TMQB612_1 (DHFR-TS)	1i9c	GLUTAMATE MUTASE (Clostridium cochlearium)	5 / 12	ILE A 94 MET A 111 SER A 62 ILE A 11 ILE A 69	None	1.10A	3clbB-1i9cA: undetectable	3clbB-1i9cA: 14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QC6_B_KANB201_2 (BIFUNCTIONAL AAC/APH)	1i9c	GLUTAMATE MUTASE (Clostridium cochlearium)	3 / 3	LEU A 87 ASP A 114 TYR A 89	None	0.53A	4qc6B-1i9cA: 0.0	4qc6B-1i9cA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_V_BEZV801_0 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 BEZ-LEU-LEU)	1i9c	GLUTAMATE MUTASE (Clostridium cochlearium)	4 / 4	ILE A 58 ILE A 86 ARG A 75 LEU A 59	None None None B12 A 800 ( 4.2A)	1.23A	5dzkh-1i9cA: 1.1 5dzkn-1i9cA: 1.1 5dzkv-1i9cA: undetectable	5dzkh-1i9cA: 20.10 5dzkn-1i9cA: 20.10 5dzkv-1i9cA: 2.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6C2M_C_SUEC1203_1 (NS3 PROTEASE)	1i9c	GLUTAMATE MUTASE (Clostridium cochlearium)	5 / 9	PHE A 108 VAL A 116 ILE A 86 ARG A 115 ASP A 133	None	1.34A	6c2mC-1i9cA: undetectable	6c2mC-1i9cA: 22.40

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3CLB_B_TMQB612_1","DHFR-TS","1i9c","GLUTAMATE MUTASE","Clostridium cochlearium",5,"ILE A  94;MET A 111;SER A  62;ILE A  11;ILE A  69","None","1.10A","3clbB-1i9cA:undetectable","3clbB-1i9cA:14.15"],["4QC6_B_KANB201_2","BIFUNCTIONAL AAC\/APH","1i9c","GLUTAMATE MUTASE","Clostridium cochlearium",3,"LEU A  87;ASP A 114;TYR A  89","None","0.53A","4qc6B-1i9cA:0.0","4qc6B-1i9cA:21.43"],["5DZK_V_BEZV801_0","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1;BEZ-LEU-LEU","1i9c","GLUTAMATE MUTASE","Clostridium cochlearium",4,"ILE A  58;ILE A  86;ARG A  75;LEU A  59","None;None;None;B12 A 800 ( 4.2A)","1.23A","5dzkh-1i9cA:1.1;5dzkn-1i9cA:1.1;5dzkv-1i9cA:undetectable","5dzkh-1i9cA:20.10;5dzkn-1i9cA:20.10;5dzkv-1i9cA:2.27"],["6C2M_C_SUEC1203_1","NS3 PROTEASE","1i9c","GLUTAMATE MUTASE","Clostridium cochlearium",5,"PHE A 108;VAL A 116;ILE A  86;ARG A 115;ASP A 133","None","1.34A","6c2mC-1i9cA:undetectable","6c2mC-1i9cA:22.40"]]