SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1i9s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 1i9s MRNA CAPPING ENZYME
(Mus
musculus) 		4 / 4 LEU A  25
PRO A  26
LEU A  27
ARG A  15
 None
None
None
IPA  A 600 (-4.1A)
 1.42A 1hrkB-1i9sA:
2.2		 1hrkB-1i9sA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 1i9s MRNA CAPPING ENZYME
(Mus
musculus) 		4 / 4 LEU A  25
PRO A  26
LEU A  27
ARG A  15
 None
None
None
IPA  A 600 (-4.1A)
 1.31A 2hrcA-1i9sA:
undetectable		 2hrcA-1i9sA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 1i9s MRNA CAPPING ENZYME
(Mus
musculus) 		4 / 4 LEU A  25
PRO A  26
LEU A  27
ARG A  15
 None
None
None
IPA  A 600 (-4.1A)
 1.44A 2hrcB-1i9sA:
2.2		 2hrcB-1i9sA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1i9s MRNA CAPPING ENZYME
(Mus
musculus) 		4 / 4 LEU A  25
PRO A  26
LEU A  27
ARG A  15
 None
None
None
IPA  A 600 (-4.1A)
 1.41A 2pnjB-1i9sA:
2.1		 2pnjB-1i9sA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		 1i9s MRNA CAPPING ENZYME
(Mus
musculus) 		4 / 5 ASP A 168
GLU A  96
GLY A  95
TYR A 169
 None
 0.95A 3w9tB-1i9sA:
0.0		 3w9tB-1i9sA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		 1i9s MRNA CAPPING ENZYME
(Mus
musculus) 		4 / 5 ASP A 168
GLU A  96
GLY A  95
TYR A 169
 None
 0.99A 3w9tD-1i9sA:
0.0		 3w9tD-1i9sA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		 1i9s MRNA CAPPING ENZYME
(Mus
musculus) 		4 / 5 ASP A 168
GLU A  96
GLY A  95
TYR A 169
 None
 1.02A 3w9tE-1i9sA:
0.0		 3w9tE-1i9sA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		 1i9s MRNA CAPPING ENZYME
(Mus
musculus) 		4 / 5 ASP A 168
GLU A  96
GLY A  95
TYR A 169
 None
 0.95A 3w9tG-1i9sA:
0.0		 3w9tG-1i9sA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1i9s MRNA CAPPING ENZYME
(Mus
musculus) 		5 / 11 PHE A 156
ALA A 152
CYH A 126
HIS A 125
LEU A  67
 None
 1.13A 4nqaA-1i9sA:
undetectable		 4nqaA-1i9sA:
18.26