SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iah'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 VAL A1652
VAL A1665
TRP A1656
 None
 0.92A 1w5uA-1iahA:
undetectable
1w5uB-1iahA:
undetectable		 1w5uA-1iahA:
6.88
1w5uB-1iahA:
6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		4 / 8 VAL A1778
VAL A1763
LEU A1682
THR A1683
 None
 0.74A 2gehA-1iahA:
undetectable		 2gehA-1iahA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 VAL A1665
TRP A1656
VAL A1652
 None
 0.83A 2izqC-1iahA:
undetectable
2izqD-1iahA:
undetectable		 2izqC-1iahA:
6.88
2izqD-1iahA:
6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 TYR A1552
GLU A1557
ASN A1559
 None
 1.03A 2y7hC-1iahA:
0.0		 2y7hC-1iahA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 PRO A1590
LEU A1593
ARG A1699
 None
 0.82A 3aqiA-1iahA:
undetectable		 3aqiA-1iahA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PY4_A_TYLA598_1
(LACTOPEROXIDASE)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		4 / 5 GLN A1675
ARG A1671
GLU A1672
PHE A1648
 None
 1.46A 3py4A-1iahA:
0.0		 3py4A-1iahA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 PHE A1686
TYR A1696
LEU A1593
 None
 0.75A 3sueB-1iahA:
undetectable		 3sueB-1iahA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 ASP A1765
LEU A1773
VAL A1703
 None
 0.70A 4jecB-1iahA:
undetectable		 4jecB-1iahA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		5 / 12 VAL A1778
LEU A1761
VAL A1763
LEU A1682
THR A1683
 None
 0.88A 4xiwG-1iahA:
undetectable		 4xiwG-1iahA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		6 / 11 GLY A1618
LYS A1646
LEU A1701
GLU A1718
PHE A1725
THR A1774
 ADP  A2002 ( 4.2A)
ADP  A2002 (-2.8A)
None
ADP  A2002 (-3.6A)
ADP  A2002 ( 3.8A)
ADP  A2002 ( 4.1A)
 0.84A 4zmeA-1iahA:
23.2		 4zmeA-1iahA:
29.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		6 / 11 GLY A1619
LYS A1646
LEU A1701
GLU A1718
PHE A1725
THR A1774
 ADP  A2002 (-3.1A)
ADP  A2002 (-2.8A)
None
ADP  A2002 (-3.6A)
ADP  A2002 ( 3.8A)
ADP  A2002 ( 4.1A)
 0.46A 4zmeA-1iahA:
23.2		 4zmeA-1iahA:
29.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		5 / 10 LYS A1646
LEU A1701
GLU A1718
PHE A1725
THR A1774
 ADP  A2002 (-2.8A)
None
ADP  A2002 (-3.6A)
ADP  A2002 ( 3.8A)
ADP  A2002 ( 4.1A)
 0.36A 4zmeB-1iahA:
23.2		 4zmeB-1iahA:
29.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		4 / 8 LEU A1706
GLY A1712
ALA A1711
SER A1710
 None
 0.78A 5f1aA-1iahA:
0.0		 5f1aA-1iahA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		5 / 12 GLY A1792
VAL A1778
PRO A1776
PHE A1648
GLY A1619
 None
None
None
None
ADP  A2002 (-3.1A)
 0.96A 5f9zA-1iahA:
undetectable		 5f9zA-1iahA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 VAL A1763
VAL A1778
GLN A1676
 None
 0.71A 5qguA-1iahA:
undetectable		 5qguA-1iahA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 VAL A1763
VAL A1778
GLN A1676
 None
 0.71A 5qgvA-1iahA:
undetectable		 5qgvA-1iahA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 VAL A1763
VAL A1778
GLN A1676
 None
 0.69A 5qgwA-1iahA:
undetectable		 5qgwA-1iahA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 VAL A1763
VAL A1778
GLN A1676
 None
 0.70A 5qgxA-1iahA:
undetectable		 5qgxA-1iahA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 VAL A1763
VAL A1778
GLN A1676
 None
 0.73A 5qh1A-1iahA:
undetectable		 5qh1A-1iahA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 VAL A1763
VAL A1778
GLN A1676
 None
 0.72A 5qh4A-1iahA:
undetectable		 5qh4A-1iahA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 VAL A1763
VAL A1778
GLN A1676
 None
 0.69A 5qh9A-1iahA:
undetectable		 5qh9A-1iahA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 VAL A1763
VAL A1778
GLN A1676
 None
 0.65A 5qhaA-1iahA:
0.0		 5qhaA-1iahA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 VAL A1763
VAL A1778
GLN A1676
 None
 0.70A 5qhfA-1iahA:
undetectable		 5qhfA-1iahA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		4 / 8 VAL A1778
VAL A1763
LEU A1682
THR A1683
 None
 0.68A 5tt3F-1iahA:
undetectable		 5tt3F-1iahA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		5 / 11 GLY A1792
GLU A1672
LEU A1796
ASN A1795
ASN A1731
 None
 1.15A 5x6yA-1iahA:
undetectable		 5x6yA-1iahA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		5 / 11 VAL A1790
GLY A1792
LEU A1796
ASN A1795
ASN A1731
 None
 1.15A 5x6yA-1iahA:
undetectable		 5x6yA-1iahA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		5 / 10 GLY A1792
GLU A1672
LEU A1796
ASN A1795
ASN A1731
 None
 1.10A 5x6yB-1iahA:
undetectable		 5x6yB-1iahA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		5 / 11 GLY A1792
GLU A1672
LEU A1796
ASN A1795
ASN A1731
 None
 1.06A 5x6yC-1iahA:
undetectable		 5x6yC-1iahA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		5 / 11 VAL A1790
GLY A1792
LEU A1796
ASN A1795
ASN A1731
 None
 1.08A 5x6yC-1iahA:
undetectable		 5x6yC-1iahA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 PHE A1791
ARG A1671
GLN A1675
 None
 1.17A 6g1pB-1iahA:
undetectable		 6g1pB-1iahA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 1iah TRANSIENT RECEPTOR
POTENTIAL-RELATED
PROTEIN
(Mus
musculus) 		3 / 3 VAL A1703
ALA A1716
GLN A1676
 None
 0.69A 6gb9A-1iahA:
undetectable		 6gb9A-1iahA:
19.78